Pharmaceutical Raw Material Tenofovir CAS 147127-20-6 Tenofovir Raw Powder
TDS
147127-20-6
Pharmaceutical Grade
99%
shenzhen
HORLDEN
1kg Per Bag, 25kg Per Drum
2026-01-29
Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceWhite Crystalline SolidChEBI: A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxy ethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.
Solid
Tenofovir (anhydrous) is a member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection. It has a role as a HIV-1 reverse transcriptase inhibitor, an antiviral drug and a drug metabolite. It is a member of phosphonic acids and a nucleoside analogue. It is a conjugate acid of a tenofovir(1-).|Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog. The antiviral activities of tenofovir were first reported in 1993 and this agent was commercially available since 2008 in the form of [tenofovir disoproxil] and [tenofovir alafenamide] in order to obtain oral bioavailability.|Tenofovir anhydrous is a Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor and Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of tenofovir anhydrous is as a Nucleoside Reverse Transcriptase Inhibitor.|Tenofovir is an acyclic nucleotide analogue of adenosine used in combination with other agents in the therapy of the human immunodeficiency virus (HIV) and as single agent in hepatitis B virus (HBV) infection. Tenofovir does not appear to be a significant cause of drug induced liver injury.|An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.Certificates-
TDS
Basic Info-
Product Name:
Tenofovir
Other Name:Phosphonic acid,P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-;Phosphonic acid,[[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-,(R)-;Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-;P-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid;(R)-9-(2-Phosphonomethoxypropyl)adenine;Tenofovir;PMPA;GS 1275;GS 1278;Tenefovir;[(2R)-1-(6-Aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid;([[(2R)-1-(6-Amino-9H-purin-9-yl)propan-2-yl]oxy]methyl)phosphonic acid
CAS No.:147127-20-6
Molecular Formula:C9H14N5O4P
InChIKeys:InChIKey=SGOIRFVFHAKUTI-ZCFIWIBFSA-N
Molecular Weight:287.21
Exact Mass:287.21
EC Number:1308068-626-2
UNII:W4HFE001U5
DSSTox ID:DTXSID9040132
ATC Code:J05AR03
HScode:29339900
Categories:
Characteristics-
PSA:
136
XLogP3:-1.6
Appearance:Solid
Density:1.79±0.1 g/cm3(Predicted)
Melting Point:276-280°C
Boiling Point:616°C
Flash Point:326.4±34.3 °C
Refractive Index:1.740
Water Solubility:H2O: 13.4 mg/mL (25 ºC)
Storage Conditions:Store at -20°C
Specific rotation:D +21° (c = 1 in 0.1M HCl)
PKA:3.8and 6.7
Dissociation Constants:3.8 and 6.7
Hazard IdentificationClassification of the substance or mixture
Serious eye damage, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H318 Causes serious eye damage
Precautionary statement(s) Prevention P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide
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Location:
9th Floor, Room 923, Building 3, Shiyuan Daguan, Xingtai 1st Street, Chanba Ecological District, Xi'an City, Shaanxi Province
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Payment Terms:
100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
