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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Retatrutide for Sale > RT Retatrutide 99% purity 5-60mg*10vials weight loss Peptide Top Quality local factory
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RT Retatrutide 99% purity 5-60mg*10vials weight loss Peptide Top Quality local factory

TDS 7465 Inquiries

Unit Price: Get Latest Price
CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

GUANGZHOU

Brand:

GuangSheng

Packaging:

5mg 10mg 15mg 20mg 30mg 60mg vials box Tin foil bag Support customization

Sample Available:

Yes

Price valid (until):

2026-02-28

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
30 days
Qualification:
Main Products:

beaty prodt

  • Product Details

  • Seller Information

  • History Price

  • Inquiry History

  • Description


      Product Detail  


    Name: Candice
    Wechat: 15360466377

    Tel:+86 15360466377

    Whatsapp:+8 52   61859189

    Email:guangsheng 1 @zgguangsheng.com

    Shop RT Retatrutide 99% purity 5-60mg*10vials weight loss Peptide Top Quality local factory-Detailed Image 1

    Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

    Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

    In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

    Retatrutide, LY3437943

    CAS#: 2381089-83-2

    Molecular Formula: C221H342N46O68

    Molecular Weight: 4731.33

    Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

    Appearance: White Powder

    Purity (HPLC): ≥99.0%

    Single Impurity (HPLC): ≤1.0%

    Sodium Content (HPLC): 5.0%-12.0%

    Moisture Content (Karl Fischer): ≤10.0%

    Peptide Content: ≥80.0%

    Storage: Store at 2-8 degrees Celsius in a dry and cool place.

    Packaging: 1g-1kg, plastic bottle

    Intended Use: For scientific research purposes

    Shop RT Retatrutide 99% purity 5-60mg*10vials weight loss Peptide Top Quality local factory-Detailed Image 2
    Shop RT Retatrutide 99% purity 5-60mg*10vials weight loss Peptide Top Quality local factory-Detailed Image 3

    Mechanism of Action and Molecular Structure of Retatrutide:

    Triple Agonist Design
    - GLP-1 receptor: Retatrutide delays gastric emptying, suppress appetite, and promote insulin secretion.
    - GIP receptor: Retatrutide enhances insulin sensitivity and regulate central satiety signals.
    - Glucagon receptor (GCGR): Retatrutide activates liver energy metabolism, promote lipolysis and glycogenolysis, and increase basal metabolic rate.
    The triple synergistic effect increases energy consumption while reducing energy intake, significantly improving weight loss effects.

    Indications and Efficacy:

    ★ Obesity Treatment:
    In the Phase II clinical trial, patients in the highest dose group (12 mg) lost an average of 24.2% weight after 48 weeks, and some patients lost more than 30%.

    ★ Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD):
    Retatrutide can reduce liver fat content by 86%, and more than 85% of patients achieve regression of liver steatosis.

    ★ Type 2 Diabetes:
    Significantly reduce glycated hemoglobin (HbA1c) and improve blood sugar control.

    ★ Potential Cardiovascular Benefits:
    Animal studies have shown that it may indirectly protect cardiovascular health by improving blood pressure and heart function, but further clinical verification is needed.



      Shipment & Document Delivery  



    Shop RT Retatrutide 99% purity 5-60mg*10vials weight loss Peptide Top Quality local factory-Detailed Image 4


      Factory  


      Company profile

    Guangsheng Technology Co., Ltd. We strive for survival, innovation and development through quality. We adhere to the business philosophy of honesty and trustworthiness, uphold the quality policy of "all based on quality standards, with customer satisfaction as the goal, pursuing novelty and people-oriented quality", and continuously improve and perfect ourselves. We are the developers and leaders of green active materials. Professional product production, product transportation and professional team services have enabled us to gain a good reputation worldwide.

     

     

    service:

    1. We supply Peptides, APIs & Intermediates and so on to satisfy your needs;  
    2. We will reply you for your inquiry in 24 hours;  
    3. Strictly on selecting raw materials . Our Q&C team will inspect every product quality strictly before delivery;

    4. Reasonable & competitive price, fast lead time ;

    5. After delivery, we will track the products for you once every two days, until you get the products. When you got the goods, if you have any questions about the problem, contact with us, we will offer the solve way for you ;

    6. 100% safe delivery, guaranteed delivery .

    Shop RT Retatrutide 99% purity 5-60mg*10vials weight loss Peptide Top Quality local factory-Detailed Image 5 Shop RT Retatrutide 99% purity 5-60mg*10vials weight loss Peptide Top Quality local factory-Detailed Image 6

    ECHEMI Editorial Reference
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
    Retatrutide (LY-3437943) was discovered by the American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors) for obesity. The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity.

    Certificates

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    InChIKeys:

    MLOLQJNKXBNWFW-SAGGEDDASA-N

    Molecular Weight:

    0

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Categories:

    Other Chemical Drugs

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    beaty prodt

    Location:

    Yongtai Jinli City Plaza, Baiyun District, Guangzhou City, Guangdong Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    30 days

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2023

  • Weekly Price

    The chart shows the price trend of the product in the past 12 months.

  • Inquiry History
    7465 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Tesa

    2 MG Oct 25, 2026
    Colombia

    Retatrutide

    15 MG Oct 25, 2026
    United States

    Retatrutide

    10 G Oct 25, 2026
    Canada

    Retatrutide

    1 KG Oct 25, 2026
    United Kingdom

    Retatrutide

    1 G Oct 25, 2026
    Netherlands

    Retatrutide

    10 MG Oct 25, 2026
    Australia

    Retatrutide

    10 MG Oct 25, 2026
    Netherlands

    Retatrutide

    20 MG Oct 25, 2026
    Germany

    Retatrutide

    1 KG Oct 25, 2026
    United Kingdom

    Retatrutide

    10 G Oct 25, 2026
    United States

    Retatrutide

    20 MG Oct 25, 2026
    Poland

    Retatrutide

    20 MG Oct 25, 2026
    United States

    Retatrutide

    10 MT Oct 25, 2026
    United States

    Retatrutide

    300 MG Oct 25, 2026
    Germany

    Retatrutide

    1 MT Oct 24, 2026
    Malta

    Retatrutide

    10 MT Oct 24, 2026
    United States

    Retatrutide

    2000 MG Oct 24, 2026
    Australia

    Retatrutide

    100 MT Oct 24, 2026
    Bulgaria

    Retatrutide

    10 PCS Oct 24, 2026
    United States

    retatrutide

    10 MT Oct 24, 2026
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