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Tacrolimus Monohydrate 109581-93-3 Tacrolimus FK-506

Name: Tacrolimus Monohydrate 109581-93-3 Tacrolimus FK-506
Brand: HORLDEN
SKU: pr2601041263
Price: 70 USD
Availability: InStock

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CAS No.:

109581-93-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Brand:

HORLDEN

Packaging:

1g/bag

Sample Available:

Yes

Price valid (until):

2026-02-04

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Xi'an Horlden Bio-Tech Co., Ltd

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide

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Product Details
Seller Information
Inquiry History

Description

Product Name	Tacrolimus Monohydrate
CAS NO.	109581-93-3
Purity	99%
Molecular Formula	C44H71NO13
MOQ	1 g

Tacrolimus monohydrate (FK506 monohydrate) is a macrolide compound. Tacrolimus monohydrate binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase, thereby inhibiting T lymphocyte signal transduction and IL-2 transcription. It has strong immunosuppressive properties.

You can ask us for quotation and product information via Email, Phone, WhatsApp and other channels.

Email: sales@horlden.com
WhatsApp/ wechat: +86 17782893353

1.What's your payment terms?

Standard terms: T/T in advance. Also L/C at sight is acceptable for large amount.

2.What's your shipping time?

We have bulk in stock, which means we can ship it to you immediately.

3.How do you ensure the quality of your products?

Strict QC with 6 steps testing from raw material purchase to finished product.

4.How do you ship the order normally?

For large qty order,ship the goods by sea. For small qty order, by air or express. We supply optional express for you, including DHL, FEDEX,UPS,TXT,EMS,and so on.

5.What's your loading port?

Usually Beijing, Shanghai, Qingdao, Tianjin, Guangzhou

ECHEMI Editorial Reference

Tacrolimus monohydrate binds to FK506 binding protein (FKBP). This complex inhibits calcineurin phosphatase (PP2B). Tacrolimus monohydrate is a mTOR-independent autophagy inducer.

Certificates

Basic Info

Product Name:

Tacrolimus hydrate

Other Name:

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-,hydrate (1:1),(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,monohydrate,[3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,monohydrate,(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-;Tsukubaenolide hydrate;Tacrolimus hydrate;Tacforius

CAS No.:

109581-93-3

Molecular Formula:

C44H69NO12.H2O

InChIKeys:

InChIKey=NWJQLQGQZSIBAF-MLAUYUEBSA-N

Molecular Weight:

822.04

Exact Mass:

821.492554

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

179

XLogP3:

log Kow = 3.03 (est)

Melting Point:

127-129°

Boiling Point:

871.7°C at 760 mmHg

Flash Point:

481ºC

Water Solubility:

DMSO: soluble 20mg/mL

Storage Conditions:

−20°C

Vapor Pressure:

8.37X10-32 mm Hg at 25 °C (est)

Specific rotation:

D23 -84.4° (c = 1.02 in chloroform)

See More Tacrolimus hydrate Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Tacrolimus hydrate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide

Location:
9th Floor, Room 923, Building 3, Shiyuan Daguan, Xingtai 1st Street, Chanba Ecological District, Xi'an City, Shaanxi Province

Payment Terms:
100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2015

Xi'an Horlden Bio-Tech Co., Ltd is committed to promoting health application products such as chemical daily necessities, APIs, pharmaceutical intermediates and Cosmetic raw materials.

We have established friendly business relationships with hundreds of customers from over 50 countries and regions. Our team is committed to providing customers with the highest quality products at reasonable prices and satisfactory service. For many years, our company has won the trust and favor of our customers with high-quality products, first-class services, and competitive prices.

We will create the highest quality and most stable supply channel for customers, adhering to the spirit of serving customers, relying on strong funds and good cooperation reputation in the industry, to provide customers with higher quality products and services. At the same time, we are willing to strengthen exchanges and sincere cooperation with domestic and foreign merchants to create a better future together. It is your best supplier.

Welcome to Xi'an Horlden Bio-Tech Co., Ltd!

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Turkey	TACROLIMUS HYDRATE	6 KG	Mar 21, 2025
India	Tacrolimus USP	500.00 G	Nov 13, 2025

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Tacrolimus Monohydrate 109581-93-3 Tacrolimus FK-506

Product Details

Seller Information