99% Purity Raw Chemical Intermediate Chlorpromazine Hydrochloride 69-09-0
69-09-0
Pharmaceutical Grade
99%
sz
j
25kg/Cardboard Drum
Yes
2026-02-06
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceChlorpromazine Hydrochloride is an antagonist of the dopamine D2, 5HT2A, potassium channel andsodium channel. Chlorpromazine binds with D2 and 5HT2A with Kis of 363 nM and 8.3 nM, respectively.
Chlorpromazine hydrochloride appears as white or creamy-white odorless crystalline powder with very bitter taste. pH (5% aqueous solution) 4.0-5.5. pH (10% aqueous solution) 4-5. (NTP, 1992)
Chlorpromazine hydrochloride appears as white or creamy-white odorless crystalline powder with very bitter taste. pH (5% aqueous solution) 4.0-5.5. pH (10% aqueous solution) 4-5. (NTP, 1992)|Chlorpromazine Hydrochloride is the hydrochloride salt form of chlorpromazine, a phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine hydrochloride exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, such as hallucinations and delusions. Chlorpromazine hydrochloride appears to exert its anti-emetic activity by blocking the dopamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting.|The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.Basic Info-
Product Name:
Chlorpromazine hydrochloride
Other Name:10H-Phenothiazine-10-propanamine,2-chloro-N,N-dimethyl-,hydrochloride (1:1);Phenothiazine,2-chloro-10-[3-(dimethylamino)propyl]-,monohydrochloride;10H-Phenothiazine-10-propanamine,2-chloro-N,N-dimethyl-,monohydrochloride;2-Chloro-10-(3-dimethylaminopropyl)phenothiazine monohydrochloride;Chloropromazine monohydrochloride;Chlorpromazine monohydrochloride;Chlorpromazinium chloride;CPZ;10-(3-Dimethylaminopropyl)-2-chlorophenothiazine monohydrochloride;Largactil monohydrochloride;Thorazine hydrochloride;Chlorpromazine hydrochloride;Chloropromazine hydrochloride;Plegomazin;Neurazine;Aminazin monohydrochloride;Ampliactil monohydrochloride;Norcozine;Propaphen;Propaphenin hydrochloride;Klorpromex;Hebanil;Klorproman;Aminazin hydrochloride;Hibernal;Megatil;Chlorazin;Taroctyl;Chloractil;Sonazine;Largaktyl;Promacid;Hibanil;Marazine;Tranzene;Promapar;Torazina;Largactil;Contomin;3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine hydrochloride;[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]dimethylamine hydrochloride;2-Chloro-10-(3-dimethylaminopropyl)-phenothiazine hydrochloride
CAS No.:69-09-0
Molecular Formula:C17H19ClN2S.ClH
InChIKeys:InChIKey=FBSMERQALIEGJT-UHFFFAOYSA-N
Molecular Weight:355.33
Exact Mass:354.072418
EC Number:200-701-3
UNII:9WP59609J6
NSC Number:226514|17479
UN Number:2811
DSSTox ID:DTXSID7024827
NCI Thesaurus Code:C47975
HScode:29173980
Categories:
Characteristics-
PSA:
31.8
XLogP3:5.41
Appearance:White to off-white or clear colorless Powder/Solution
Density:1.077 g/cm3 (15 C)
Melting Point:180 °C
Boiling Point:450.1ºC at 760 mmHg
Flash Point:9℃
Refractive Index:1.4436 (20ºC)
Water Solubility:In water, 2.55X10-3 g/L (2.55 mg/L) at 24 deg C
Storage Conditions:-20°C Freezer
Vapor Pressure:5.17X10-6 mm Hg at 25 deg C (est)
Toxicity:Oral-Rat LD50 145 mg/kg; Oral-Mouse LD50: 135 mg/kg
Flammability characteristics:Combustible, decomposes toxic nitrogen oxides, chlorides, sulfur oxides when burned
Air and Water Reactions:Decomposes on exposure to air and light. becoming yellow, pink and, finally, violet. Water soluble.
Reactive Group:Amines, Phosphines, and Pyridines
Reactivity Profile:CHLORPROMAZINE HYDROCHLORIDE is incompatible in aqueous solution with sodium salts of barbiturates and other alkaline solutions. Solutions may be stabilized by addition of antioxidants and storing under nitrogen. (NTP, 1992)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Acute toxicity - Category 2, Inhalation
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H330 Fatal if inhaled
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P320 Specific treatment is urgent (see ... on this label).
Storage P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Chlorpromazine hydrochloride oral solutions, tablets, and injection should be stored at a temperature less than 40 deg C, preferably between 15-30 deg C; freezing of the oral solutions and injection should be avoided. ... Chlorpromazine suppositories should be stored in well-closed containers between 15-30 deg C. ...Chlorpromazine hydrochloride oral concentrate solution should be dispensed in amber glass bottles.
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Seller Information
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Business Type:
Trader
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Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332
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Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
$50 million-$100 million
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Total Employees:
51-100
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Year of Establishment:
2012
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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