| Items | Specifications |
| roducts Name: | Survodutide |
| CAS No.: | 2805997-46-8 |
| Appearance: | White powder |
Description:
Glucagon receptor/glucagon-like peptide-1 receptor (GCGR/GLP-1R) double agonist survodutide(BI 456906) has been recognized as breakthrough therapy by the Center for Drug Evaluation (CDE) of the China National Medical Products Administration (NMPA). It is intended for the treatment of metabolic dysfunction-related steatohepatitis (MASH). Survodutide is a glucagon receptor/glucagon-like peptide-1 receptor (GCGR/GLP-1R) dual agonist with a unique mechanism of action. The glucagon receptor agonist component of Survodutide increases energy expenditure and directly affects the liver, helping to improve liver fibrosis. The GLP-1 agonist group can effectively reduce appetite and increase satiety at the same time.
Survodutide is a drug under development, mainly used to treat obesity and type 2 diabetes. It is a dual receptor agonist that acts on both the GLP-1 (glucagon-like peptide-1) receptor and the GCG (glucagon) receptor, and works by regulating blood sugar levels and promoting weight loss.
Main features:
Dual receptor agonism mechanism: Survodutide activates both GLP-1 and GCG receptors, the GLP-1 receptor helps lower blood sugar and suppress appetite, while the GCG receptor promotes energy consumption and fat decomposition.
Clinical research progress: Currently, Survodutide has entered the clinical trial stage, and preliminary results show that it has significant effects in reducing weight and improving blood sugar control.
Potential advantages: Compared with single receptor agonists, Survodutide may provide more comprehensive metabolic improvements, especially in the combined treatment of obesity and type 2 diabetes.
Applicable population:
Obese patients
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