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API Atomoxetine HCl

Name: API Atomoxetine HCl
Brand: Hyper Chem
SKU: pr2601081241
Price: 700 USD
Availability: InStock

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CAS No.:

82248-59-7

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Sample Available:

Yes

Price valid (until):

2026-02-08

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Atomoxetine HCl
CAS number	82248-59-7
Description	Atomoxetine is a norepinephrine reuptake inhibitor approved for the treatment of attention deficit hyperactivity disorder (ADHD). The brand name is Strattera. The initial therapeutic effects of atomoxetine usually take 2–4 weeks to become apparent. There has been some suggestion that atomoxetine might be a helpful adjunct in people with major depression, especially in cases where ADHD occurs comorbidly to major depression.
Related CAS	83015-26-3 (free base) 82248-59-7 (HCl)
Synonym	Atomoxetine; Tomoxetine; Tomoxetina; Tomoxetinum; (-)-Tomoxetine; Strattera; Atomoxetine HCl; Atomoxetine Hydrochloride;
Appearance	Solid powder
Quality Standard	USP, EP, BP, CP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Atomoxetine HCl More Info

1. General Overview

Atomoxetine Hydrochloride is a selective norepinephrine reuptake inhibitor (SNRI) primarily used in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD). Unlike many other ADHD medications, it is a non-stimulant, which offers a distinct safety profile and mechanism of action. It is commonly marketed under the brand name Strattera.

2. Mechanism of Action

Atomoxetine HCl works by selectively inhibiting the presynaptic norepinephrine transporter. This action increases the levels of norepinephrine (and indirectly dopamine) in the prefrontal cortex of the brain. By enhancing neurotransmission in this region, it helps regulate executive functions such as attention, impulsivity, and hyperactivity.

3. Key Applications & Indications

Attention-Deficit/Hyperactivity Disorder (ADHD): It is approved for use in children, adolescents, and adults.

Off-label Uses: Sometimes prescribed for treatment-resistant depression, anxiety disorders, or cognitive dysfunction associated with various conditions, though ADHD remains the primary indication.

4. Chemical & Physical Properties

CAS Number: 82248-59-7

Molecular Formula: C17H21NO · HCl

Molecular Weight: 291.82 g/mol

Appearance: White to off-white powder

Solubility: Soluble in water, methanol, and ethanol.

5. Advantages & Safety Profile

Non-Controlled Substance: Because it is not a stimulant, it is not classified as a controlled substance in many regions (e.g., not a Schedule II drug in the US), reducing the risk of abuse and diversion.

24-Hour Coverage: It is taken orally and is usually dosed once or twice daily, providing continuous symptom control throughout the day and night.

Non-Abuse Potential: It does not produce the euphoric effects associated with stimulant medications.

6. Manufacturing & Quality Control

For pharmaceutical manufacturing, Atomoxetine HCl requires strict adherence to Good Manufacturing Practices (GMP). Key quality control parameters include:

High Purity (typically >99%).

Low levels of related substances/impurities.

Compliance with pharmacopoeial standards (USP, EP, JP).

7. Storage & Handling

Storage: Should be stored in a cool, dry place, protected from light and moisture.

Shelf Life: Typically 2-3 years when stored under recommended conditions.

Key Vocabulary for Business & Technical Communication

Non-stimulant: Refers to drugs that do not increase dopamine/serotonin acutely like Adderall or Ritalin.

SNRI: Serotonin-Norepinephrine Reuptake Inhibitor (though Atomoxetine is selective for Norepinephrine).

Bioavailability: The proportion of a drug that enters the bloodstream.

Half-life: The time required for the concentration of the drug in the plasma to reduce by half (approx. 5 hours for children, 21 hours for adults).

Pharmacokinetics: The study of how the body processes the drug (absorption, distribution, metabolism, excretion).

Sample Sentence for a Product Catalog

Our Atomoxetine HCl API (Active Pharmaceutical Ingredient) is produced under strict GMP conditions, ensuring high purity and stability for use in ADHD therapeutic formulations.

Shop API Atomoxetine HCl-Detailed Image 1

ECHEMI Editorial Reference

Atomoxetine Hcl(LY 139603; Tomoxetine Hcl) is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). IC50 value: 5 nM (Ki for human NET)Target: NETAtomoxetine displays minimal affinity for a range of other neurotransmitter receptors and transporters (Ki > 1 μM). Atomoxetine is antidepressant and a commonly used non-stimulant treatment for Attention deficit hyperactivity disor
Atomoxetine hydrochloride is the hydrochloride salt of atomoxetine. It has a role as an antidepressant and an adrenergic uptake inhibitor. It contains an atomoxetine.|Atomoxetine is a selective norepinephrine reuptake inhibitor used primarily for therapy of attention deficit hyperactivity disorder. Atomoxetine has been linked to a low rate of serum aminotransferase elevations and to rare cases of acute, clinically apparent liver injury.|Atomoxetine Hydrochloride is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft. The effect on cognitive brain function may result in improved attention and decreased impulsivity and activity levels.|A propylamine derivative and selective ADRENERGIC UPTAKE INHIBITOR that is used in the treatment of ATTENTION DEFICIT HYPERACTIVITY DISORDER.

Basic Info

Product Name:

Atomoxetine hydrochloride

Other Name:

Benzenepropanamine,N-methyl-γ-(2-methylphenoxy)-,hydrochloride (1:1),(γR)-;Benzenepropanamine,N-methyl-γ-(2-methylphenoxy)-,hydrochloride,(R)-;Benzenepropanamine,N-methyl-γ-(2-methylphenoxy)-,hydrochloride,(γR)-;LY 139603;Tomoxetine hydrochloride;(R)-(-)-Tomoxetine hydrochloride;(R)-Tomoxetine hydrochloride;Atomoxetine hydrochloride;(R)-(-)-N-Methyl-3-[(2-methylphenyl)oxy]-3-phenyl-1-aminopropane hydrochloride;Strattera;(R)-N-Methyl-3-(2-methylphenoxy)-3-phenylpropylamine hydrochloride;Atemoxetine hydrochloride;(R)-N-Methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine hydrochloride

CAS No.:

82248-59-7

Molecular Formula:

C17H21NO.ClH

InChIKeys:

InChIKey=LUCXVPAZUDVVBT-UNTBIKODSA-N

Molecular Weight:

291.82

Exact Mass:

291.138977

EC Number:

200-659-6

UNII:

57WVB6I2W0

DSSTox ID:

DTXSID2044266

NCI Thesaurus Code:

C47405

HScode:

2922299090

Categories:

Other Chemical Drugs

Characteristics

PSA:

21.3

XLogP3:

4.91750

Appearance:

solid

Melting Point:

160-161 °C

Boiling Point:

389°C at 760 mmHg

Flash Point:

9℃

Water Solubility:

In water, 54.64 mg/L at 25 deg C (est)

Storage Conditions:

2-8°C

Vapor Pressure:

1.31X10-5 mm Hg at 25 deg C (est)

Specific rotation:

D25 -38.01°; 36525 -177.26° (c = 1 in methanol); D23 -41.37° (c = 1.02 in methanol); D25 -40.3° (c = 0.94 in ethanol)

Collision Cross Section:

162.4 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Atomoxetine hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Serious eye damage, Category 1

Acute toxicity - Category 2, Inhalation

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H318 Causes serious eye damage H330 Fatal if inhaled H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection. P273 Avoid release to the environment.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P320 Specific treatment is urgent (see ... on this label). P391 Collect spillage.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Atomoxetine hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Company Certificates
- Certification Report by Bureau Veritas
About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
Chile	Atomoxetine hydrochloride	2 KG	Apr 17, 2026
Guatemala	Atomoxetine HCl	1 KG	Dec 31, 2023
United States	atomoxetine	100 MG	Apr 9, 2026

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API Atomoxetine HCl

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