Resiquimod RC07406
1 Inquiries
144875-48-9
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceResiquimod is an imidazoquinoline.|A substance being studied in the treatment of some types of skin cancer. When put on the skin, resiquimod causes some immune cells to make certain chemicals that may help them kill tumor cells. It is also being studied to find out if adding it to a tumor vaccine improves the antitumor immune response. It is a type of imidazoquinoline and a type of immunomodulator.|Resiquimod is an imidazoquinolinamine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages, and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activation of other transcription factors. This may lead to an increase in mRNA levels and subsequent production of cytokines, especially interferon-alpha (INF-a) and other cytokines, thereby enhancing T-helper 1 (Th1) immune responses. In addition, topical application of resiquimod appears to activate Langerhans' cells, leading to an enhanced activation of T-lymphocytes. Due to its immunostimulatory activity, this agent may potentially be useful as a vaccine adjuvant.Basic Info
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Product Name:
Resiquimod
Other Name:1H-Imidazo[4,5-c]quinoline-1-ethanol,4-amino-2-(ethoxymethyl)-α,α-dimethyl-;4-Amino-2-(ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol;S 28463;R 848;Resiquimod;1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol;Resimiquimod;4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline;1-[4-Amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol;171742-32-8;208711-44-8
CAS No.:144875-48-9
Molecular Formula:C17H22N4O2
InChIKeys:InChIKey=BXNMTOQRYBFHNZ-UHFFFAOYSA-N
Molecular Weight:314.38200
Exact Mass:314.38
UNII:V3DMU7PVXF
DSSTox ID:DTXSID7040603
NCI Thesaurus Code:C63958
HScode:2933990090
Categories:
Characteristics-
PSA:
86.19000
XLogP3:3.05530
Density:1.28g/cm3
Boiling Point:553.6ºC at 760mmHg
Flash Point:288.6ºC
Refractive Index:1.634
Vapor Pressure:4.33E-13mmHg at 25°C
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Egypt
Imiquimod
1 KG Sep 25, 2024 Post an enquiry for this product
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