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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Retatrutide for Sale > 99% White Powder High-Purity Peptide RT Retatrutide RT5 RT10 RT15 RT20 RT30 RT60
99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60 buy - large image1
99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60 buy - image1
99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60 buy - image2
99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60 buy - image3
99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60 buy - image4
99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60 buy - image5
99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60 buy - image6

99% White Powder High-Purity Peptide RT Retatrutide RT5 RT10 RT15 RT20 RT30 RT60

5924 Inquiries

Unit Price: Get Latest Price
CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

HONGKONG

Brand:

YUNI

Packaging:

10mg*10vials/box

Price valid (until):

2026-02-15

Company Type:
Trader
Location:
China
Qualification:
Main Products:

beaty prodt

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Name: Lilian
    Wechat:yi970803bo

    Whatsapp:+852  61856606

    Email:guangsheng2@zgguangsheng.com

    Shop 99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60-Detailed Image 1

    Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

    Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

    In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

    Retatrutide is a new type of multi-target peptide drug developed by Eli Lilly and Company of the United States, it is a trip

    le receptor agonist of GLP-1R/GIPR/GCGR. Its core mechanism is to regulate the metabolic process by activating glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) and glucagon (GCG) receptors at the same time, and is used for the treatment of obesity and type 2 diabetes. The following are its key features:Shop 99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60-Detailed Image 2


    Items Specifications
    Product Name Retatrutide
    CAS No. 2381089-83-2
    Molecular Formula C187H291N45O59
    Appearance White Powder
    Packaging 10mg/vial, 10vials/box
    MOQ 10 vials

    Mechanism of Action and Molecular Structure of Retatrutide:

    1)Triple Agonist Design
    - GLP-1 receptor: Retatrutide delays gastric emptying, suppress appetite, and promote insulin secretion.
    - GIP receptor: Retatrutide enhances insulin sensitivity and regulate central satiety signals.
    - Glucagon receptor (GCGR): Retatrutide activates liver energy metabolism, promote lipolysis and glycogenolysis, and increase basal metabolic rate.
    The triple synergistic effect increases energy consumption while reducing energy intake, significantly improving weight loss effects.

    2) Structural Optimization
    - Based on the GIP skeleton modification, non-natural amino acids (such as α-methylleucine at position 13) are introduced to enhance receptor affinity.
    - The half-life is extended to 7 days through fatty acid side chain modification, supporting subcutaneous injection once a week.

    Shop 99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60-Detailed Image 3


    Clinical Effects and Core Data of Retatrutide:

    1) Outstanding Weight Loss Effect:
    - 48 weeks of treatment: The average weight loss in the 12mg dose group reached 24.2%, significantly better than existing drugs (such as Semaglutide and Tirzepatide).
    - Gender differences:
     Women have a more significant weight loss effect (28.5% vs. men 21.2%).
    - Dose dependence:
     From the starting dose of 2mg to 12mg, the weight loss ratio increases with the dose.

    Comparison of Weight Loss Effects at Different Doses (48-Week Data):

    Doses 4mg 8mg 12mg
    Weight Loss Ratio ~8.7% ~17.5% ~24.2%
    Waist Circumference Reduction -2.1cm -6.1cm -10.2cm


    Before and after weight loss:

    Shop 99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60-Detailed Image 4

    2) Comprehensive Improvement of Metabolism:

    - Blood sugar control: Significantly reduce glycated hemoglobin (HbA1c), and doses above 4mg are better than dulaglutide.
    - Cardiovascular metabolism: Improve triglyceride, cholesterol and blood pressure levels, potentially reducing cardiovascular risks.
    - Expanded indications: Used in research for metabolic-related diseases such as polycystic ovary syndrome (PCOS).

    Shop 99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60-Detailed Image 5

    Indications and Efficacy:

    ★ Obesity Treatment:
    In the Phase II clinical trial, patients in the highest dose group (12 mg) lost an average of 24.2% weight after 48 weeks, and some patients lost more than 30%.

    ★ Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD):
    Retatrutide can reduce liver fat content by 86%, and more than 85% of patients achieve regression of liver steatosis.

    ★ Type 2 Diabetes:
    Significantly reduce glycated hemoglobin (HbA1c) and improve blood sugar control.

    ★ Potential Cardiovascular Benefits:
    Animal studies have shown that it may indirectly protect cardiovascular health by improving blood pressure and heart function, but further clinical verification is needed.

    Shop 99% White Powder High-Purity Peptide  RT  Retatrutide  RT5 RT10 RT15 RT20 RT30 RT60-Detailed Image 6

    Market Prospects and Challenges:

    ◎ Differentiation Advantages:
    Compared with existing GLP-1 single-target (such as Semaglutide) or dual-target drugs (such as Tirzepatide), the triple mechanism of Retatrutide has greater potential in weight loss and metabolic improvement.

    ◎ Cost and Accessibility:
    Currently, the production cost of peptide drugs is relatively high, but the long-acting properties of Retatrutide may reduce the frequency of medication and improve patient compliance.



    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    LY3437943;Retatrutide;GIPR/GLP-1R;Retatrutide/LY3437943/GIPR/GLP-1R;Retaglutide;Retatrutide acetate;LY3437943Retatrutide;Retalutide

    CAS No.:

    2381089-83-2

    Molecular Weight:

    0

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Categories:

    Other Chemical Drugs

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

  • Seller Information
    Business Type:

    Trader

    Main Products:

    beaty prodt

    Location:

    Yongtai Jinli City Plaza, Baiyun District, Guangzhou City, Guangdong Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    30

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2023

  • Inquiry History
    5924 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Retatrutide 2381089-83-2

    3 MT Mar 28, 2026
    United Kingdom

    Retatrutide - 2381089-83-2

    1 G Feb 10, 2026
    United States

    Retatrutide CAS 2381089-83-2 10mg vial

    20 MT Mar 7, 2026
    United States

    Factory Retatrutide API 99% Purity CAS 2381089-83-2

    5 KG Nov 10, 2025
    United Kingdom

    Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA

    1 MT Mar 22, 2026
    United States

    2381089-83-2

    100 G Feb 24, 2026
    United States

    2381089-83-2

    100 MT Dec 9, 2023
    United States

    Retatrutide 2381089-83-2

    200 MG May 16, 2026
    United Kingdom

    2381089-83-2 retatrutide

    300 MG Feb 13, 2026
    Austria

    Retatrutide CAS 2381089-83-2 10mg vial

    20 PCS Feb 10, 2026
    United States

    GLP-1 / GIP Retatrutide cas 2381089-83-2

    1 MT Oct 16, 2024
    United States

    Retatrutide 2381089-83-2 wholesale

    500 MT Nov 3, 2023
    United States

    Retatrutide CAS 2381089-83-2 99%

    10 PCS Feb 21, 2026
    Poland

    CAS 2381089-83-2 (Custom Peptide)

    40 MT Apr 10, 2026
    Austria

    Peptide Retatruide CAS 2381089-83-2

    100 MT Apr 4, 2026
    Palestine

    Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service

    10 MG Mar 16, 2026
    United States

    Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service

    20 MG Feb 4, 2026
    Singapore

    Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service

    100 MG Jun 28, 2025
    United States

    Tirzepatide 99.9% Liquid 2381089-83-2 TeruiOP

    1 MT Sep 6, 2023
    United States

    Retatrutide/LY3437943/GIPR/GLP-1R 98% Powder 2381089-83-2 Senwayer

    1 G Sep 3, 2023
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