API 99% Albuterol sulfate White Raw Power CAS 51022-70-9 factory outlet With Best QUality

Albuterol Sulfate More Info

Albuterol Sulfate is the sulfate salt form of albuterol, a selective short-acting β2-adrenergic receptor agonist, with the CAS Registry Number 51022-70-9. Its molecular structure is based on a phenylethanolamine backbone, featuring a tertiary-butyl group on the amine side chain which confers selectivity for the β2-adrenoceptor subtype. The sulfate salt formation enhances the drug's stability and solubility, making it suitable for inhalation, oral, and injectable formulations. It is typically a white or off-white crystalline powder.

The primary mechanism of action involves selective agonism of β2-adrenergic receptors located on bronchial smooth muscle cells. Activation of these receptors stimulates intracellular adenylate cyclase, increasing cyclic AMP levels. This leads to the activation of protein kinase A, which in turn inhibits myosin phosphorylation and lowers intracellular calcium concentration, resulting in smooth muscle relaxation. The effect is rapid bronchodilation, decreased airway resistance, and improved mucociliary clearance, providing relief from bronchoconstriction.

Albuterol sulfate is a cornerstone medication for the treatment and prevention of bronchospasm in obstructive airway diseases. Its main clinical applications include the acute relief of symptoms in asthma, exercise-induced bronchoconstriction, and chronic obstructive pulmonary disease. It is also used in the management of acute hyperkalemia by driving potassium intracellularly. Formulations include pressurized metered-dose inhalers, dry powder inhalers, nebulizer solutions, oral tablets, syrups, and intravenous solutions, allowing for versatile use in both outpatient and emergency settings.

The drug is most commonly administered via inhalation, which delivers the medication directly to the lungs, maximizing therapeutic effect while minimizing systemic side effects. Onset of action when inhaled is within minutes, with peak effect occurring in about 30 to 60 minutes and a duration of action of 4 to 6 hours. Oral and intravenous routes are used in specific situations but are associated with a higher incidence of systemic adverse effects due to greater bioavailability outside the lungs.

The safety profile of albuterol is generally favorable when used at recommended doses, but it is not without risks. Common side effects are related to systemic β2-adrenergic stimulation and include tachycardia, palpitations, tremor, headache, and hypokalemia. Excessive use can lead to paradoxical bronchospasm and loss of bronchoprotective effect. The most serious risk is the potential for fatal exacerbations of asthma if over-relied upon instead of anti-inflammatory controller therapy. It is contraindicated in patients with known hypersensitivity and must be used with caution in those with cardiovascular disease, diabetes, or hyperthyroidism.

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Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

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For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

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Suitable for more than 50kg 
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Suitable for more than 500kg      
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For sample orders: 
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2. Packaging photo
3. COA, MSDS, etc
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5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

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Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

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HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.