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Pitolisant HCl

2 Inquiries

Unit Price: Get Latest Price
CAS No.:

362665-56-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2026-02-08

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Name

    Pitolisant HCl

    CAS number

    903576-44-3

    Description

    Pitolisant, also known as Tiprolisant, BF2649 and Ciproxidine, is a histamine receptor inverse agonist/antagonist selective for the H3 subtype. It has stimulant and nootropic effects and may have several medical applications such as treatment of narcolepsy.

    Related CAS

    362665-56-3 (free base) 903576-44-3 (HCl) 362665-57-4 (oxalate)

    Synonym

    BF2.649; BF2649; BF-2649; BF2649; FUB-649, FUB649, FUB 649, BF2.649; BF 2.649; HBS-101; HBS 101; HBS101; Ciproxidine; Pitolisant, Tiprolisant; Pitolisant HCl; Pitolisant hydrochloride.

    Appearance

    Solid powder

    Quality Standard

    USP, EP, BP, CP

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 0 - 4 for short term (days to weeks) or -20 for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China


    Pitolisant HCl More Info

    General Description:

    Pitolisant HCl is a first-in-class histamine H3 receptor antagonist/inverse agonist. It is approved for the treatment of excessive daytime sleepiness (EDS) in adults with narcolepsy and obstructive sleep apnea (OSA). Unlike traditional central nervous system stimulants, Pitolisant is not a controlled substance. Chemically, it is a white crystalline powder that is soluble in water, ethanol, and methylene chloride, but practically insoluble in cyclohexane.

    Chemical Identity:

    Chemical Name: 1-{3-[3-(4-chlorophenyl)propoxy]propyl}piperidine, hydrochloride

    CAS Number: 903576-44-3

    Molecular Formula: C₁₇H₂₆ClNO·HCl

    Molecular Weight: 332.31 g/mol

    Mechanism of Action:

    Pitolisant HCl acts as a potent and selective antagonist/inverse agonist at histamine H3 receptors (with a Ki value of 0.16 nM for human H3 receptors). By blocking these autoreceptors and heteroreceptors, it enhances the synthesis and release of histamine in the brain. This mechanism promotes wakefulness and reduces excessive daytime sleepiness by activating the histaminergic system.

    Indications:

    Narcolepsy: It is approved for the treatment of EDS in adult patients with narcolepsy.

    Obstructive Sleep Apnea (OSA): It is indicated for the treatment of EDS in adult patients with OSA, used in conjunction with continuous positive airway pressure (CPAP) therapy.


    Shop Pitolisant HCl-Detailed Image 1

    Basic Info
    Product Name:

    Pitolisant

    CAS No.:

    362665-56-3

    Molecular Formula:

    C17H26ClNO

    InChIKeys:

    InChIKey=NNACHAUCXXVJSP-UHFFFAOYSA-N

    Exact Mass:

    295.85

    Categories:

    Inhibitors

    Characteristics
  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Pitolisant

    1 G Jan 8, 2026
    United States

    Pitolisant

    1 G Mar 27, 2026
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