Top Quality Botulinum toxin

Name:  Lynn
Wechat：  15914422644

Tel：+86  15914422644

Whatsapp: +852 6252 8290

Email：    guangsheng 5   @zgguangsheng.com

1. Core Molecular & Physicochemical Specifications

2. Mechanism of Action

1. Lung Epithelial Repair: Enhances the integrity and function of bronchial and alveolar epithelial cells, promoting the regeneration of ciliated cells and alveolar type II cells to maintain airway clearance and surfactant secretion.
2. Surfactant Augmentation: Stimulates alveolar type II cells to increase pulmonary surfactant production, improving lung compliance and gas exchange efficiency.
3. Anti-inflammatory Activity: Reduces the expression of pro-inflammatory cytokines (e.g., TNF-α, IL-6), mitigating neutrophilic inflammation and preventing lung tissue fibrosis.
4. Geroprotective Effects: Reactivates senescent DNA in lung cells, reversing age-related declines in lung function and exerting gonadotropin-protective properties.

3. Key Research Applications

3.1 Respiratory Disease Research

• COPD Model Studies: Restores damaged lung epithelium, reduces inflammatory cell infiltration, and improves lung function in chronic obstructive pulmonary disease models.
• Asthma & Allergic Inflammation: Mitigates airway hyperresponsiveness and reduces allergic inflammation by regulating cytokine balance.
• Pulmonary Fibrosis: Inhibits fibroblast activation and extracellular matrix deposition, alleviating lung scarring.

3.2 Aging & Gerontology Research

• Investigates reversal of age-related lung function decline via DNA reactivation.
• Explores gonadotropin-protective effects and systemic anti-aging mechanisms.

3.3 Basic Respiratory Biology

• Studies on epithelial cell regeneration, surfactant metabolism, and inflammatory signaling pathways in lung tissue.

4. Handling & Usage Guidelines

4.1 Reconstitution

• Reconstitute with sterile water, BAC water, or PBS to desired concentration (e.g., 1 mg/mL).
• Gently vortex to ensure complete dissolution; avoid vigorous shaking to prevent peptide denaturation.

4.2 Administration Routes (Research Use)

4.3 Safety Precautions

• Research Only: Not for human clinical use or consumption.
• Handling: Use personal protective equipment (gloves, lab coat, goggles) to avoid direct contact.
• Disposal: Follow local laboratory waste disposal regulations for peptide solutions and containers.

5. Quality Control & Assurance

• Purity Testing: HPLC analysis confirms ≥98% purity, with no detectable impurities above 0.5%.
• Identity Verification: Mass spectrometry (MS) confirms the molecular weight matches the theoretical value.
• Endotoxin Level: <0.01 EU/μg, ensuring no pyrogenic contamination.
• Sterility: Aseptically processed to meet research-grade sterility standards.