CAS:12020-86-9 MGF

Name:  Lynn
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1. Basic Information

2. Mechanism of Action

1. Satellite Cell Activation & Myogenesis: Selectively activates muscle satellite cells, inhibits terminal myocyte differentiation, promotes myoblast proliferation, accelerates myofiber regeneration, and induces muscle hypertrophy.
2. Protein Synthesis & Tissue Repair: Upregulates protein synthesis-related genes to enhance repair of injured muscle and bone; improves chondrocyte survival under mechanical stress via YAP signaling, facilitating cartilage repair.
3. Cardioprotection & Neurorepair: Boosts myocardial blood supply, alleviates ischemia-reperfusion injury; promotes neuronal regeneration and reduces functional impairment post-neural damage.
4. Anti-senescence: Extends the half-life of tissue repair mediators, optimizes cell lifespan, and maintains tissue homeostasis.

3. Core Efficacy & Applications

• Muscle Repair & Growth: Accelerates post-exercise muscle recovery, reverses disuse atrophy, increases muscle mass and strength, shortens recovery cycles for athletes and fitness enthusiasts.
• Bone & Cartilage Health: Assists in repairing exercise-induced cartilage damage, enhances bone density, and reduces sports-related skeletal injury risks.
• Cardiac & Neural Protection: Adjuvant intervention for post-ischemic myocardial injury, peripheral nerve damage, and neurodegenerative disease management.
• Anti-aging & Tissue Maintenance: Delays senescence of muscle and bone tissues, suitable for preventing age-related tissue function decline in the elderly.

4. Dosage & Administration

• Route: Intramuscular injection, administered directly into injured or target muscle areas.
• Dosage: 50–200μg daily on training days for performance enhancement or muscle repair; typical cycle: 2–3 months (adjust based on individual needs).
• Precautions: Strict sterile operation for reconstitution; use reconstituted solution within 6 months; avoid overdose.

5. Safety & Warnings

• Potential Risks: Overdose may cause blood glucose fluctuations, fluid retention, joint pain; long-term safety data remain insufficient.
• Contraindications: Prohibited for pregnant/lactating women, minors, severe diabetics, and cancer patients.
• Regulatory Note: Mostly in research phase; some applications (e.g., performance enhancement) are regulated in certain regions. Consult healthcare professionals and comply with local regulations before use.

6. Research Progress

• Preclinical studies confirm MGF’s efficacy in muscle, cartilage, and cardiac tissue repair; its satellite cell activation mechanism provides a novel target for muscle injury treatment.
• Clinical applications are still exploratory, relying mainly on animal experiments and small-scale human trials. Large-scale, long-term clinical studies are needed to clarify its human efficacy and safety boundaries.