High Quality raw Peptides Purity 99% Na-931 Raw Powder CAS 136054-22-3

It primarily works by blocking the ghrelin receptor (GHS-R1a), thereby inhibiting the gastric emptying and appetite-increasing effects of ghrelin.

As a ghrelin receptor antagonist, (D-Lys3)-GH-6 can reduce food intake and weight gain. Furthermore, it exhibits autophagy effects on skeletal muscle, showing potential applications in muscle metabolism and repair.

[D-Lys3]-GH-6 is a multifunctional peptide compound primarily used to investigate the mechanism of action of ghrelin receptors and its potential applications in appetite regulation, gastric emptying, and weight management.

STORAGE CONDITION

Storage: Store at -20℃ degrees Celsius in a dry and cool place.

Storage Condition: Store at -20°C Solubility in DMSO: 3mg/mL (0.73 mM)

The storage conditions of  Semaglutide vary depending on the form. The powder should be stored at − 20 ° C for 3 years and 4 ° C for 2 years. After dissolved in solvent, it should be stored at − 80 ° C for 6 months and at − 20 ° C for 1 month. In addition, Semaglutide should be refrigerated before opening, and can be kept refrigerated or stored at room temperature for 56 days after opening.

Matching Image Description 1: Appearance of Sermaglutide Raw Powder

Quality and Technical Specifications

1. Purity: The purity detected by HPLC can reach up to 99.8%, and the content determined by the anhydrous and salt-free calculation method is between 95.0% - 105.0%. The maximum single impurity is only 0.68%, and the total impurity content is 2.11%, which is far below the industry limit.
2. Key Impurity Control: The content of fatty acid side chain - related impurities is 0.95%, and the polymer protein content detected by SEC - HPLC is 1.35%, both meeting the strict pharmaceutical raw material standards.
3. Safety Indicators: The moisture content tested by the Karl Fischer method is 5.8%, which is less than the limit of 10.0%. The bacterial endotoxin content is less than 2 EU/mg, which is much lower than the standard of less than 10 EU/mg, ensuring biological safety.
4. Biological Activity: Through cAMP - based cell assay, its biological activity reaches 105% of the reference standard, maintaining excellent biological efficacy.

Matching Image Description 2: Quality Inspection Report and Testing Equipment

Packaging and Storage

1. Packaging Specifications: It provides flexible packaging options according to different usage scenarios. Common specifications include 1g/bottle, 10g/bottle, 100g/bottle and 1kg/bottle. The powder is packed in aluminum foil bags for vacuum sealing, and then put into a sealed glass bottle or paper drum to prevent moisture and pollution.
2. Storage Conditions: It should be stored in a dry, cool and well-ventilated environment, avoiding direct sunlight and high temperature. The recommended storage temperature is 2 - 8°C. When stored as required, the shelf life can be as long as 24 months.
3. Transportation Notes: During transportation, thermal insulation packaging should be used to avoid temperature fluctuation. Repeated freezing and thawing should be strictly prohibited to prevent the loss of biological activity.

Matching Image Description 3: Packaging Specifications of Bulk Raw Powder

Biological Mechanisms and Application Fields

1. Core Biological Mechanism: It can specifically bind to the GLP - 1 receptor, stimulate insulin secretion when blood glucose rises, inhibit the secretion of glucagon, slow down gastric emptying, and enhance the sense of satiety of the human body, so as to achieve the dual effects of regulating blood glucose and controlling weight.
2. Pharmaceutical Application: It is the core raw material for the production of drugs for type 2 diabetes and obesity treatment. The prepared preparations (such as injections and oral tablets) have the characteristics of long-acting effects and are widely used in clinical practice.
3. Scientific Research Value: It is a key research object in the fields of peptide drugs, metabolic diseases and endocrinology. Researchers use it to carry out in-depth studies on the mechanism of GLP - 1 receptor regulation and the development of new long-acting peptide drugs.

Matching Image Description 4: Mechanism Diagram and Application Scenarios

Matching Image Description 5: Application of Finished Products Derived from Raw Powder

Company Profile 

Hangzhou Beiputai Biomedical Co., Ltd. was established in 2023 and is a high-tech enterprise specializing in the research and development and sales of peptides and related derivatives. Currently, the company has a peptide research and development center in the Overseas Students' Innovation Park of Qiantang District, Hangzhou, equipped with several well-equipped peptide research and development production lines and multiple sets of large-scale peptide synthesis and analysis equipment, including imported Agilent high-performance liquid chromatography analyzers, AB mass spectrometers, high-performance liquid chromatography preparative instruments, and other equipment. The company's main scientific researchers all have over ten years of experience in peptide research and development and can meet the personalized customization requirements of different customers. At present, we can provide: GLP-1 class peptides (semaglutide/teplizumab/retaglutide, etc.), small molecule mimetic peptides, FAPI, PSMA, OCT and other radiolabeled peptide precursors (RDC precursors), PDC peptide compounds, peptide inhibitors (aldolpeptide/FMK/CMK/AMOK, etc.), fluorescent enzyme substrates (PNA/AMC/AFC/R110, etc.), Ser-Thr glycopeptides, isotope-labeled peptides, macrocyclic peptides, MAPS complex antigen peptides, fluorescent-labeled peptides, cell-penetrating peptides, etc., to meet the application needs of different customers. Currently, the company has over 100 mature peptide products, with an annual production capacity of over 100kg of peptides.