N-(2-Benzoyl-4-chlorophenyl)-2-chloro-N-methylacetamide Dideu

**Product Name: N-(2-Benzoyl-4-chlorophenyl)-2-chloro-N-methylacetamide**
**CAS No.: 6021-21-2**
**Molecular Formula: C₁₆H₁₃Cl₂NO₂**
**Molecular Weight: 322.19 g/mol**
**Purity: ≥98% (HPLC), customizable**
**Appearance: White to off-white crystalline powder**

**Product Overview**

N-(2-Benzoyl-4-chlorophenyl)-2-chloro-N-methylacetamide is a specialized pharmaceutical intermediate and reference compound with significant importance in quality control and analytical chemistry. This structurally complex molecule features a benzophenone core with strategically positioned chloro and acetyl substituents, providing excellent stability and well-defined spectral characteristics. The compound serves as a critical analytical standard, particularly known as Diazepam Impurity B, making it indispensable for pharmaceutical manufacturers and testing laboratories requiring precise impurity profiling and method validation in benzodiazepine drug analysis.

**Main Applications**

**Pharmaceutical Quality Control & Testing**
Essential reference standard for HPLC, GC, and LC-MS method development and validation in the analysis of diazepam and related benzodiazepine compounds. Used extensively in stability testing, impurity profiling, and batch release testing to ensure compliance with pharmacopeial standards including USP, EP, and JP requirements.

**Analytical Chemistry Research**
Valuable calibration standard for developing and validating analytical methods for trace impurity detection in complex pharmaceutical matrices. The compound's well-characterized properties make it ideal for studying degradation pathways and establishing detection limits in sensitive analytical systems.

**Pharmaceutical R&D**
Key intermediate in the synthesis of novel benzodiazepine derivatives and structural analogs for structure-activity relationship (SAR) studies. Researchers utilize this compound as a building block for developing new CNS-active compounds with potentially improved therapeutic profiles and reduced side effects.

**Forensic Toxicology**
Critical reference material for forensic laboratories conducting drug testing and toxicology screening. The compound serves as a positive control and identification standard for detecting and quantifying benzodiazepine-related substances in biological samples and seized drug materials.

**Regulatory Compliance Testing**
Indispensable for contract research organizations (CROs) and quality control laboratories performing regulatory submissions and compliance testing. The compound supports ICH Q3A and Q3B guidelines for impurity qualification and reporting in pharmaceutical manufacturing.

**Product Features**

- **High Purity Standard**: ≥98% HPLC purity with strict control of residual solvents and trace impurities to ensure analytical accuracy
- **Excellent Stability**: Stable crystalline form with minimal degradation under proper storage conditions, ensuring long-term reliability as a reference standard
- **Comprehensive Characterization**: Fully characterized by NMR, MS, IR, and elemental analysis with complete spectral data available
- **Low Impurity Profile**: Strict control of related substances and degradation products to meet stringent pharmaceutical requirements
- **Batch-to-Batch Consistency**: Rigorous quality control protocols ensuring consistent performance across different production batches
- **Solubility Profile**: Soluble in DMSO, methanol, and acetonitrile for easy preparation of analytical solutions

**Packaging & Storage**

**Packaging Options**: 10 mg, 50 mg, 100 mg, 250 mg, 1 g in amber glass vials with PTFE-lined caps under inert atmosphere; custom quantities available
**Storage Conditions**: Store at -20°C or below in airtight containers, protected from light and moisture to maintain stability
**Shelf Life**: 24 months when stored under recommended conditions
**Transport**: Shipped on dry ice with temperature monitoring to ensure integrity during transit

**Why Choose Us**

- **Pharmaceutical Grade Manufacturing**: GMP-compliant production facilities with advanced synthesis and purification capabilities ensuring consistent quality and regulatory compliance
- **Comprehensive Analytical Support**: State-of-the-art QC laboratory with HPLC-DAD, LC-MS/MS, NMR, and FTIR for complete product characterization and certification
- **Regulatory Documentation**: Complete documentation package including Certificate of Analysis (COA), spectral data, and regulatory support files (DMF, CEP available upon request)
- **Technical Expertise**: Dedicated team of pharmaceutical chemists and analytical specialists providing method development support and application guidance
- **Global Supply Chain**: Established logistics network with customs clearance expertise serving pharmaceutical companies and laboratories worldwide
- **Custom Services**: Custom synthesis, packaging, and analytical testing services available to meet specific customer requirements

*Note: This product is intended for research, analytical, and pharmaceutical quality control use only. Not for human or veterinary therapeutic use. All specifications subject to change without notice. Contact us for customized purity requirements, special packaging requests, or bulk pricing inquiries. Certificate of Analysis and Safety Data Sheet available upon request.*