Ticlopidine hydrochloride RC08152
53885-35-1
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceTiclopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM.Target: Adenosine diphosphate (ADP)Ticlopidine (trade name Ticlid) is an antiplatelet drug in the thienopyridine family. Ticlopidine hydrochloride inhibits platelet aggregation with IC50 of ~2 μM in men. Like clopidogrel, it is an adenosine diphosphate (ADP) receptor inhibitor. It is used in patients in whom aspirin is not tolerated, or in whom dual antiplatelet
Ticlopidine Hydrochloride is the hydrochloride salt form of ticlopidine, a thienopyridine derivative with anticoagulant property. Ticlopidine hydrochloride irreversibly inhibits adenosine-diphosphate (ADP)-induced platelet-fibrinogen binding by binding to the glycoprotein (GP) IIb/IIIA complex, one of the two purinergic receptors activated by ADP. Inhibition of the receptor activation causes the inhibition of adenylyl cyclase, results in decreased levels of cyclic adenosine monophosphate and thereby interferes with platelet membrane function and subsequent, platelet-platelet interaction, release of platelet granule constituents and prolongation of bleeding time.|An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.Basic Info-
Product Name:
Ticlopidine hydrochloride
Other Name:Thieno[3,2-c]pyridine,5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydro-,hydrochloride (1:1);Thieno[3,2-c]pyridine,5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydro-,hydrochloride;Ticlopidine hydrochloride;53-32C;Panaldine;Ticlodone;Ticlosin;Tiklid;Anagregal;Ticlodox;Caudaline;4C32;Panapidin;Nichistate;Clid
CAS No.:53885-35-1
Molecular Formula:C14H14ClNS.ClH
InChIKeys:InChIKey=MTKNGOHFNXIVOS-UHFFFAOYSA-N
Molecular Weight:300.25
Exact Mass:299.030212
EC Number:258-837-4
UNII:A1L4914FMF
NSC Number:759165
DSSTox ID:DTXSID80202141
NCI Thesaurus Code:C47756
HScode:2934999090
Categories:
Characteristics-
PSA:
31.5
Appearance:1
Density:1.37 g/cm3
Melting Point:190 °C
Boiling Point:367.3°C at 760 mmHg
Flash Point:175.9ºC
Water Solubility:soluble to 100 mM in water and to 100 mM in DMSO.
Storage Conditions:Desiccate at RT
Toxicity:Oral-rat LD50: 1780 mg/kg; Oral-Mouse LD50: 600 mg/kg
Flammability characteristics:Flammable; burning produces toxic sulfur oxides, nitrogen oxides and hydrogen chloride fumes
Collision Cross Section:154.8 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Serious eye damage, Category 1
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H302 Harmful if swallowed
H318 Causes serious eye damage
H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
P391 Collect spillage.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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