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Jinlan 98+ EP/BP/USP Vandetanib

Name: Jinlan 98+ EP/BP/USP Vandetanib
Brand: Jinlan
SKU: pr26012240676
Price: 164 USD
Availability: InStock

2 Inquiries

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CAS No.:

443913-73-3

Grade:

medical grade

Content:

98%

Port:

Shanghai/Ningbo/Qingdao

Brand:

Jinlan

Packaging:

25kg/Cardboard Drum

Price valid (until):

2026-03-01

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Peptides,API,Intermediate

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Vandetanib (443913-73-3)

Basic Product Description

CAS Number: 443913-73-3

Chemical Name: 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline

Molecular Formula: C₂₂H₂₄BrFN₄O₂

Molecular Weight: 475.35 g/mol

Synonyms: Caprelsa®, ZD6474

Related Categories: Multi-targeted EGFR/VEGFR2/RET Tyrosine Kinase Inhibitor (TKI), Oral Small Molecule TKI, Medullary Thyroid Cancer & EGFR/RET-Positive NSCLC Therapeutic

Key Highlight: A potent oral multi-targeted TKI with inhibitory activity against EGFR, VEGFR2 and RET kinases; approved for the treatment of unresectable locally advanced or metastatic medullary thyroid cancer (MTC); also exhibits clinical activity in EGFR/RET-positive non-small cell lung cancer (NSCLC); exerts dual anti-proliferative and anti-angiogenic effects by blocking aberrant kinase signaling pathways, and has moderate oral bioavailability with mild central nervous system (CNS) penetration.

Basic Info

Product Name:

Vandetanib

Other Name:

4-Quinazolinamine,N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-;N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine;ZD 6474;Vandetanib;4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline;Zactima;CH 331;Caprelsa;N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine;N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(N-methylpiperidin-4-ylmethoxy)quinazolin-4-amine;AZD 6474;AZD6474;AZD-6474;338992-00-0;660412-36-2;790713-55-2

CAS No.:

443913-73-3

Molecular Formula:

C22H24BrFN4O2

InChIKeys:

InChIKey=UHTHHESEBZOYNR-UHFFFAOYSA-N

Molecular Weight:

475.35

Exact Mass:

475.35

EC Number:

1806241-263-5

UNII:

YO460OQ37K

NSC Number:

760766|744325

DSSTox ID:

DTXSID1046681

NCI Thesaurus Code:

C2737

ATC Code:

L01XE|L - Antineoplastic and immunomodulating agents

HScode:

2933990090

Categories:

Other Chemical Drugs

Characteristics

PSA:

59.5

XLogP3:

4.9

Appearance:

White solid

Density:

1.4±0.1 g/cm3

Melting Point:

242 °C

Boiling Point:

538°C at 760 mmHg

Flash Point:

279.3℃

Refractive Index:

1.629

Water Solubility:

In water, 330 uM (pH 7.4); approx 650 uM (pH approx 6.5)

Storage Conditions:

-20°C Freezer

Vapor Pressure:

1.86X10-11 mm Hg at 25 deg C (est)

Henrys Law Constant:

Henry's Law constant = 6.14X10-17 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa1 = 4.46; pKa2 = 13.80 (est)

Experimental Properties:

Hydroxyl radical reaction rate constant = 3.23X10-10 cu cm/molec-sec at 25 °C (est)

See More Vandetanib Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Reproductive toxicity, Category 1B

Specific target organ toxicity â repeated exposure, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H360 May damage fertility or the unborn child H373 May cause damage to organs through prolonged or repeated exposure H410 Very toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P318 IF exposed or concerned, get medical advice. P319 Get medical help if you feel unwell. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Vandetanib Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Peptides,API,Intermediate

Location:
Room 606, Building 1, Fu Yi Commercial Center, Shangcheng District, Hangzhou City, Zhejiang Province - 1

Payment Terms:
100% TT in advance

Average lead Time:
275

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
51-100

Year of Establishment:
2020

Hangzhou Jinlan Pharm-Drugs Technology Co., Ltd (with its export company Hangzhou Royall Import & Export Co.,Ltd.) is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int' l Airport and Shanghai Pudong Int' l Airport, the transportation and production environment are excellent. JINLAN PHARMA mainly business includes: 1) API, Pharmaceutical Intermediates, CMO, CRO, CDMO and so on. 2) Pharmaceutical Equipment such as: Distilled Water Machinery, Mixer, Sterilizer and so on.

JINLAN PHARM focus on:

■ Contrast Agent

■ Anti-COVID APIs

■ Respiratory System APIs

■ Anti-tumor & Anti-Cancer APIs

■ Anti-Diabetes APIs

■ Anti-HCV & Anti-HBV APIs

■ Anti-HIV APIs

■ Peptides

■ Pharmaceutical Intermediates

■ CMO, CRO, CDMO

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Pakistan	Vandetanib	1 KG	Jul 24, 2025
Pakistan	Vandetanib	1 KG	May 27, 2025

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