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Home > Organic Chemistry > Quinones > β-Alanine for Sale > Top quality Ademetionine disulfate tosylate
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Top quality Ademetionine disulfate tosylate

33 Inquiries

Unit Price: Get Latest Price
CAS No.:

107-95-9

Grade:

Industrial Grade

Content:

99%

Port:

Qingdao

Packaging:

25kg/drum;1kg/bag

Price valid (until):

2026-03-01

Company Type:
Trader
Location:
Hongkong, China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    1. What is Ademetionine Disulfate Tosylate?

    Ademetionine disulfate tosylate is a stable salt form of S-Adenosylmethionine (SAMe), a critical physiological compound found naturally in all living cells. SAMe is involved in numerous biochemical processes, primarily functioning as the body's primary methyl donor. This specific salt form (disulfate tosylate) is engineered for enhanced stability and bioavailability compared to the native SAMe molecule, which is inherently unstable and degrades easily, making it unsuitable for use in pharmaceuticals or supplements.

    2. Primary Function and Mechanism of Action

    The core function of this compound is to supplement the body's levels of SAMe. Once absorbed and circulating, it participates in three fundamental biochemical pathways:

    • Transmethylation: This is its most well-known role. SAMe donates its methyl group (-CH3) to a vast array of substrates, including DNA, phospholipids, proteins, and neurotransmitters. This process is vital for:

      • Maintaining Cell Membrane Fluidity: Via the synthesis of phosphatidylcholine.

      • Neurotransmitter Synthesis: Involved in the production of dopamine, serotonin, and norepinephrine.

    • Transsulfuration: SAMe is a precursor to sulfur-containing compounds like glutathione, the body's most potent endogenous antioxidant. This pathway is crucial for liver detoxification processes and protecting cells from oxidative damage.

    • Aminopropylation: SAMe is a precursor for the synthesis of polyamines, compounds like spermidine and spermine, which are essential for cell growth, proliferation, and repair.

    3. Key Applications and Uses

    Due to its central role in these pathways, this form of SAMe is used therapeutically for:

    • Liver Health and Function: It is extensively used to support liver function, particularly in cases of intrahepatic cholestasis (impaired bile flow) and to support detoxification pathways by boosting glutathione levels.

    • Joint Health and Comfort: It plays a role in the synthesis of proteoglycans, which are essential components of cartilage, making it a common supplement for supporting joint structure and function.

    • Mood and Cognitive Support: Through its role in synthesizing and metabolizing neurotransmitters, it is used to support emotional well-being and maintain a balanced mood.

    4. Distinction from Dietary SAMe

    SAMe is present in small amounts in virtually all living tissues, but it cannot be obtained effectively through diet, as it is broken down in the digestive tract. Ademetionine disulfate tosylate is a synthetic, stabilized pharmaceutical-grade form designed for oral administration to effectively raise systemic SAMe levels.

    ECHEMI Editorial Reference
    White powder This is a secondary amino acid, which is formed in vivo by the degradation of dihydrouracil and carnosine. Because neuronal uptake and neuronal receptor sensitivity to β-alanine have been demonstrated, the compound may be a false transmitter replacing GABA. A rare genetic disorder, hyper-β-alaninemia, has been reported. It is used as a flavor enhancer, flavoring agent, nutrient supplement or adjuvant. β-Alanine has a slightly sweet taste. White crystalline powderChEBI: A natural
    Solid|Colourless needles;
    Beta-alanine is a naturally-occurring beta-amino acid comprising propionic acid with the amino group in the 3-position. It has a role as an inhibitor, an agonist, a human metabolite, a fundamental metabolite and a neurotransmitter. It is a conjugate acid of a beta-alaninate. It is a tautomer of a beta-alanine zwitterion.|beta-Alanine is an amino acid formed in vivo by the degradation of [dihydrouracil] and [carnosine]. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.|An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
    Beta-alanine is a non-proteogenic amino acid that is produced endogenously in the liver. In addition, humans acquire beta-alanine through the consumption of foods such as poultry and meat. By itself, the ergogenic properties of beta-alanine are limited; however, beta-alanine has been identified as the rate-limiting precursor to carnosine synthesis, and has been consistently shown to increase levels of carnosine in human skeletal muscle. Doses of 4 to 6 g/day of beta-alanine have been shown to increase muscle carnosine concentrations by up to 64 % after 4 weeks, and up to 80 % after 10 weeks. Baguet et al. demonstrated that individuals vary in the magnitude of response to 5 to 6 weeks of betaalanine supplementation (4.8 g/day), with high responders increasing muscle carnosine concentrations by an average of 55 %, and low responders increasing by an average of only 15 %. The difference between high and low responders seems, at least in part, to be related to baseline muscle carnosine content and muscle fiber composition.β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.
    White powder

    Basic Info
    Product Name:

    β-Alanine

    Other Name:

    BETA-AMINO-PROPIONIC ACID;H-GLY(C*CH2)-OH;H-BETA-ALA-OH;RARECHEM EM WB 0001;NH2-(CH2)2-COOH;2-AMINOPROPIONIC ACID;H-BAla-OH;H-beta-Ala-OH~3-Aminopropionic acid

    CAS No.:

    107-95-9

    Molecular Formula:

    C3H7NO2

    InChIKeys:

    UCMIRNVEIXFBKS-UHFFFAOYSA-N

    Molecular Weight:

    89.09

    Exact Mass:

    89.09

    BRN:

    906793

    EC Number:

    203-536-5

    UNII:

    11P2JDE17B

    NSC Number:

    7603

    TSCA:

    TSCA listed

    DSSTox ID:

    DTXSID0030823

    Color/Form:

    White

    HScode:

    29224920

    Categories:

    Quinones

    Characteristics
    λmax:

    λ: 260 nm Amax: ≤0.02λ: 280 nm Amax: ≤0.02

    PSA:

    63.3

    XLogP3:

    -3

    Appearance:

    White Crystalline Powder

    Density:

    1,437 g/cm3

    Melting Point:

    202 °C (dec.)(lit.)

    Boiling Point:

    237.1±23.0 °C(Predicted)

    Flash Point:

    204-206°C

    Refractive Index:

    1.4650 (estimate)

    Water Solubility:

    Soluble in water(550g/L). Slightly soluble in alcohol. Insoluble in ether and acetone.

    Storage Conditions:

    Store at RT.

    Flammability characteristics:

    Non flammable

    Odor:

    at 100.00 %. odorless

    PH:

    6.0-7.5

    PKA:

    3.55(at 25℃)

    Dissociation Constants:

    3.63 (at 5 °C)

    Critical Temperature & Pressure:

    Keep in dark place,Inert atmosphere,Room temperature

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

    Location:

    Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $50 million-$100 million

    Total Employees:

    51-100

    Year of Establishment:

    2012

    We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

    In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

    Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

    "Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

  • Inquiry History
    33 Inquiries
    Country Product Purchase Quantity Date Posted
    Russia

    Inositol (B8)

    20 MT Sep 1, 2026
    India

    Beta-Alanine

    100.00 KG Jun 29, 2026
    United States

    Beta alanine powder

    4000 KG May 6, 2026
    India

    beta-Alanine

    500 KG Apr 29, 2026
    Spain

    β-Alanine (beta alanine)

    1 MT Mar 9, 2026
    Germany

    Potassium Sorbate

    50.00 KG May 8, 2025
    Germany

    L-carnitine

    25.00 KG May 8, 2025
    Pakistan

    β-Alanine (beta-alanine)

    50.00 KG May 6, 2025
    United States

    Beta alanine

    50 KG Apr 1, 2025
    South Korea

    β-Alanine

    1 MT Dec 4, 2024
    Australia

    beta alanine

    80 KG Nov 20, 2024
    Colombia

    Beta Alanine

    1 KG Oct 30, 2024
    India

    beta-alanine

    1 KG Sep 29, 2024
    United States

    β -Alanine (beta-alanine)

    1 KG Aug 26, 2024
    Turkey

    BETA-ALANINE

    1 MT May 28, 2024
    Romania

    β-Alanine

    2 MT Mar 12, 2024
    Indonesia

    Beta-alanine

    300 KG Mar 7, 2024
    United States

    ß-Alanine (Beta-Alanine, 3-Aminopropanoic acid) CAS #

    120250 KG Feb 6, 2024
    India

    N-Acetyl-L-Tyrosine

    10.00 KG Jan 29, 2024
    India

    L-Arginine

    50.00 KG Jan 29, 2024
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