Low price Cosmetic Copper GhkCU Peptide Lyophilized Powder 50mg/vial China Peptide Supplier

Name: jane

WeChat and WhatsApp： +8615226891795

Email:jane@xtkstech.cn

Welcome to contact me

The copper peptide GHK is a tripeptide having the primary structure Gly-L-His-L-Lys. It is a natural chelator with a high affinity for  Cu2+. The resulting complex is commonly referred to as GHK-Cu. It was first isolated from human plasma, but is also present in saliva and urine.

    Copper peptides are generally small protein fragments with a high affinity for cations. Plasma GHK-Cu levels at age 20 are about 200 µg ml-1, but drop to 80 µg ml-1 at age 60. In humans, GHK-Cu promotes wound healing, stimulates glycogen and glycosaminoglycan synthesis in skin fibroblasts and blood vessel growth, has anti-inflammatory and antioxidant properties, and attracts immune system cells. Recent studies have shown that it can modulate the expression of a large number of human genes, generally by restoring the expression of these genes corresponding to the healthy state. Synthetic GHK-Cu is used in cosmetics and as an ingredient in so-called “repairing” and “anti-aging” products.

In studies on the affinity of GHK for copper, where the histidine residue was replaced by a synthetic amino acid, it was shown that the glycine residue plays an essential role in copper binding, while the lysine residue can interact with copper only in basal. At physiological pH, lysine can interact with a cell receptor. Thanks to GHK's ability to interact with both copper and a cellular receptor, it can transport copper in and out of cells. The small size of the GHK molecule allows it to circulate rapidly in the extracellular space and easily access cellular receptors

    The structure of the GHK-Cu complex has been studied in detail by X-ray crystallography, electron paramagnetic resonance, X-ray absorption spectrometry, NMR spectroscopy or even by titration. In this complex, the Cu2+ cation is coordinated to the imidazole of the side chain of the histidine residue, and to the atom of the deprotonated peptide bond between glycine and histidine residues. Insofar as such a structure does not explain the great stability of this complex, whose decimal logarithm of the dissociation constant is worth log10(K) = 16.44, against 8.68 for the GH-Cu complex, which is similar in structure to the GHK-Cu complex, it has been suggested that another GHK atom is involved in stabilizing the complex with copper. It could be the carboxylic oxygen atom of the lysine4 residue.

Hongbai Technology Co., Ltd. is a branch of Changsha Duole Biological Co., Ltd.，The company is a pioneering force in the biotechnology sector. At the core of our operations is the unwavering commitment to our guiding principles: "Quality First, Service Supreme."Our mission is to spearhead advancements in biotechnology by consistently upholding the highest standards of quality and service.

  Through innovation and excellence, we aim to contribute to the betterment of global health and well-being.As a leading peptide manufacturer, we have a R&D team composed of senior scientists and engineers, which continues to explore and innovate, and is committed to developing safer, more effective, and more market-competitive peptide products. Our primary focus encompasses a range of products, including weight loss peptides, cosmetic peptides, and customized peptides. Notable among our weight loss peptide offerings are Tirzepatide,Semaglutide，Retatrutide, and others.

  Provides reliable and timely custom manufacturing services for API following stringent quality system and close communication with the Clients.We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market, our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.

  With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.The company adheres to the policy of "customer first, reputation commitment, quality assurance, professional service", and its products are sold at home and abroad. We look forward to establishing long-term business relations with overseas on the basis of mutual benefit in the near future. If you are interested in our products or our company, please feel free to contact us for more details!

FAQ:
Q1:How to send order?
A:Pls send the specification and quantities to by email or messages, and we check the order confirmation with you.

Q2:Do you have samples for our reference?
A:Sure,we can offer sample,the customer will pay the freight.

Q3:Any discount if order more?
A:Sure,the price is negotiable,price depends on quantity of orders.

Q4:What about the delivery time?
A:Ship within 1-2 days after confirming payment (excluding Chinese holidays).7-14 working days to arrive your address.

Q5:What kind of payment terms do you accept?
A:Payment can be made by Bank transfer, BTC,Credit Card,TT,Paypal,Alipay,Wechat,Visa,Mastercard,
Appple Pay,Google Pay.