Erdosteine RC09748
84611-23-4
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceErdosteine inhibits lipopolysaccharide (LPS)-induced NF-κB activation.
Erdosteine is a N-acyl-amino acid.|Erdosteine is a drug that causes a breakdown of mucus, also known as a mucolytic agent. It is a thiol derivative produced for the clinical management of chronic obstructive bronchitis, in addition to infective exacerbations of chronic bronchitis. This drug contains sulfhydryl groups which are released after erdosteine undergoes hepatic first pass metabolism. Three active metabolites result and possess mucolytic activity in addition to free radical scavenging activity. Erdosteine acts to control mucus production and control its viscosity while increasing mucociliary transport. It also combats the effects of free radicals resulting from cigarette smoke. Erdosteine has been shown to be safe and well tolerated in clinical trials. Erdosteine 300mg twice daily reduced cough (both frequency and severity) and sputum viscosity more quickly and more effectively than placebo and reduced the adhesivity of sputum more effectively than ambroxol 30mg twice daily. Co-administration of erdosteine and amoxicillin in patients with acute infective exacerbation of chronic bronchitis resulted in higher concentrations of the antibiotic in the sputum, leading to earlier and more pronounced amelioration of clinical symptoms compared with placebo. Erdosteine is associated with a low incidence of adverse events, most of which are gastrointestinal and generally mild.Basic Info-
Product Name:
Erdosteine
Other Name:Acetic acid,2-[[2-oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]thio]-;Acetic acid,[[2-oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]thio]-;2-[[2-Oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]thio]acetic acid;Erdosteine;RV 144;Dithiosteine;Secresolv;Erdostin;Mucotec;2-[2-Oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid;2-([[(2-Oxothiolan-3-yl)carbamoyl]methyl]sulfanyl)acetic acid;105426-14-0
CAS No.:84611-23-4
Molecular Formula:C8H11NO4S2
InChIKeys:InChIKey=QGFORSXNKQLDNO-UHFFFAOYSA-N
Molecular Weight:249.31
Exact Mass:249.31
EC Number:1312995-182-4
DSSTox ID:DTXSID8048735
ATC Code:R05CB15|R - Respiratory system
HScode:2934999090
Categories:
Characteristics-
PSA:
134
XLogP3:-0.1
Density:1.5±0.1 g/cm3
Melting Point:156-158 °C
Boiling Point:590.4°C at 760 mmHg
Flash Point:310.8±30.1 °C
Refractive Index:1.615
Storage Conditions:Refrigerator
Toxicity:LD50 in mice and rats (g/kg): >10 orally; >3.5 i.v. (Gonella)
Hazard IdentificationClassification of the substance or mixture
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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