Streptomycin RC06941
57-92-1
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceCrystalline Powder
Solid
Streptomycin is a amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class It has a role as an antimicrobial agent, an antimicrobial drug, an antibacterial drug, a protein synthesis inhibitor, a bacterial metabolite and an antifungal agrochemical. It is an antibiotic antifungal drug, an antibiotic fungicide and a member of streptomycins. It derives from a streptidine. It is a conjugate base of a streptomycin(3+).|Streptomycin is an aminoglycoside antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by binding to the 30S ribosomal subunit of susceptible organisms and disrupting the initiation and elongation steps in protein synthesis. It is bactericidal due to effects that are not fully understood.|Streptomycin is an Aminoglycoside Antibacterial and Antimycobacterial.|Streptomycin is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. Streptomycin is usually used in combination with agents that are known to be hepatotoxic and the role of streptomycin in liver injury has been difficult to assess, but most information suggests that streptomycin is not hepatotoxic.|Streptomycin is an aminoglycoside antibiotic derived from Streptomyces griseus with antibacterial activity. Streptomycin irreversibly binds to the 16S rRNA and S12 protein within the bacterial 30S ribosomal subunit. As a result, this agent interferes with the assembly of initiation complex between mRNA and the bacterial ribosome, thereby inhibiting the initiation of protein synthesis. In addition, streptomycin induces misreading of the mRNA template and causes translational frameshift, thereby results in premature termination. This eventually leads to bacterial cell death.|An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.Basic Info-
Product Name:
Streptomycin
Other Name:D-Streptamine,O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-;Streptomycin;D-Streptamine,O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-;O-2-Deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-D-streptamine;NSC 14083;2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-α-glucopyranosyl)-3-formylpentofuranoside;Streptomycin A;Agrimycin;Neodiestreptopab;Agrept;12672-24-1;47814-83-5;47816-81-9;82958-69-8;364062-67-9;880764-37-4;883721-83-3;934544-71-5;958849-24-6;1135443-27-4;1071756-76-7
CAS No.:57-92-1
Molecular Formula:C21H39N7O12
InChIKeys:InChIKey=UCSJYZPVAKXKNQ-HZYVHMACSA-N
Molecular Weight:581.57
Exact Mass:581.57
EC Number:223-286-0
UNII:Y45QSO73OB
DSSTox ID:DTXSID4023597
NCI Thesaurus Code:C61952
Color/Form:Hygroscopic powder
ATC Code:A - Alimentary tract and metabolism|J - Antiinfectives for systemic use
HScode:2941200000
Categories:
Characteristics-
PSA:
336
XLogP3:-6.4
Appearance:Solid
Density:2.0±0.1 g/cm3
Melting Point:194 °C
Boiling Point:872.9±75.0 °C at 760 mmHg
Flash Point:481.7±37.1 °C
Refractive Index:1.762
Water Solubility:1.28e+01 g/L
Storage Conditions:2-8°C
Vapor Pressure:5.82X10-28 mm Hg at 25 deg C (est)
Toxicity:Oral-Rat LD50: 9000 mg/kg
Flammability characteristics:Combustion produces toxic nitrogen oxide gas
Odor:Odorless or nearly so
Taste:Slightly bitter taste
PH:Highly polar organic base
Henrys Law Constant:Henry's Law constant = 8.41X10-44 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa1 = 11.2; pKa2 = 13.1; pKa3 = 13.4; pKa3 = 13.8 (hydroxyl) (est)
Collision Cross Section:231 Ų [M+H]+ [CCS Type: TW, Method: calibrated with Waters Major Mix]|228.5 Ų [M+Na]+ [CCS Type: TW, Method: calibrated with Waters Major Mix]
Experimental Properties:Stable at <2pH<9 but unstable in strong acids and alkalis|Most salts are hygroscopic and deliquescent on exposure to air, but are not affected by air or light. The salts are very soluble in water but almost insoluble in alcohol, chloroform, ether. Solutions are levarotatory. /Streptomycin salts/|Light tan solid at standard temperature and pressure. MP 168 °C. Bulk density 1.78 g/mL. Solubility: >200 g/100 mL in water. Not photosensitive /Streptomycin sulfate/|White or practically white powder; hygroscopic; pH (1 in 5 solution) between 4.5 and 7.0 /Streptomycin sulfate/|Clear, colorless to yellow, viscous liquid /Streptomycin sulfate injection/|Specific optical rotation: -84 deg at 25 °C/D; solubility in mg/ml at about 28 °C: water greater than 20; methanol greater than 20; ethanol 0.90; isopropanol 0.12; isoamyl alc 0.117; petroleum ether 0.02; carbon tetrachloride 0.042; ether 0.01 /Streptomycin trihydrochloride/|Streptomycin solutions are not precipitated by alkali hydroxides or carbonates (except that calcium carbonate may be precipitated in solutions of the double salt with calcium chloride) or by alkaloid precipitants such as iodine TS, mercuric-potassium iodide TS, or trinitrophenol TS.
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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