GHK Cu Copper Peptide;L-Lysine,glycyl-L-histidyl-;Copper Peptide powder (GHK-cu);GHK Cu Copper Peptide GHK.Cu GHK-Cu;Ahk-cu;Liver Cell Growth Factor(G

# Copper Tripeptide-1 (GHK-Cu) (CAS: 49557-75-7) ### The Scientifically Validated "Skin Repair Engine" ## 1. Molecular Profile - Chemical Name: Copper Tripeptide-1 (GHK-Cu) - CAS No.: 49557-75-7 - Molecular Formula: C₁₄H₂₄N₆O₄·Cu - Molecular Weight: 401.93 - Appearance: Blue crystalline powder - Solubility: Excellent water solubility; maximum stability at pH 5-7 - Nature: Small molecular protein, a premium cosmetic active ingredient with multi-dimensional skin care effects ## 2. Core Efficacy ### ① Deep Hydration & Skin Revitalization Stimulates skin vitality, relieves reduced skin function caused by stress, water shortage and environmental pollution, and imparts regenerative energy to the skin. ### ② Anti-Inflammation & Skin Barrier Repair Quickly inhibits the expression of inflammatory factors to effectively reduce skin inflammation, alleviates redness, itching, stinging and other symptoms caused by hormone dependence, and significantly improves skin with red blood streaks. As an effective skin repair agent, it rapidly restores cell proliferation activity, stimulates collagen synthesis, smooths skin wounds quickly, and enhances the skin's self-repair ability. ### ③ Promotes Collagen & Elastin Synthesis Tightens the skin, reduces the formation of fine lines, and maintains a youthful skin state. It also boosts blood vessel growth and enhances the skin's antioxidant capacity. #### Related Experimental Conclusion Cultured adult human dermal fibroblasts (HDFa) were incubated with GHK-Cu at concentrations of 0.01nM, 1nM and 100nM. Tests confirmed that GHK-Cu **significantly increases the production of collagen and elastin in HDFa cells** with minimal concentration dependence, demonstrating a potent effect in promoting the synthesis of collagen and elastin. ## 3. Application Guidelines ### ① Recommended Dosage 100-5000ppm in cosmetic formulations ### ② Optimal Synergistic Combinations - Anti-Aging Synergy: Hyaluronic Acid (enhance moisturization) + Retinol (promote epidermal renewal) - Barrier Repair: Ceramide (strengthen lipid layer) + Asiaticoside (anti-sensitivity) ### ③ Compatibility Taboos 1. Avoid compounding with caprylyl hydroxamic acid, EDTA-2Na, carnosine, glycine, hydroxyl/ammonium ion-containing substances, glucose, allantoin, aldehyde group-containing compounds, etc., to prevent precipitation or discoloration of the formulation. 2. Production process requirements: Protect from light and keep at low temperature (<25℃) to prevent active ingredient degradation.