MONOBENZONE powder 4-Benzyloxyphenol CAS 103-16-2

_{(1) Monobenzone is the monobenzyl ether Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water.
(2) Monobenzone is a compound used as a topical drug for medical depigmentation. The topical application of monobenzone in animals decreases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes thus, bringing about permanent dipigmentation in vitiligo patients.
(3) Monobenzone powder can be compounded to make a depigmenting cream. It is used to whiten patchy skin and create and even skin tone that is pale and smooth.
(4) Monobenzone USP, is a strong depigmentation agent, used to treat the patients suffering from vitiligo.
(5) Monobenzone 20% ointment is used specifically for vitiligo.}

1. Monobenzone is a compound used as a topical drug for medical depigmentation.
2. The topical application of monobenzone in animals decreases the excretion of melanin from melanocytes.
3. The same action is thought to be responsible for the depigmenting effect of the drug in humans.
4. Monobenzone may cause destruction of melanocytes and permanent depigmentation.
5. The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo.
6. The epidermis is normal except for the absence of identifiable melanocytes.

Monobenzone is used to treat the loss of skin color (vitiligo). It works by permanently removing color from normal skin located around skin with vitiligo.
Do not use this medication for other skin color conditions (e.g., freckling, age spots, etc.)

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