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efficient Melanotan 2

92 Inquiries

Unit Price: Get Latest Price
CAS No.:

121062-08-6

Grade:

Industrial Grade

Content:

99%

Port:

Qingdao

Brand:

N/A

Packaging:

1kg/bag;25kg/drum

Price valid (until):

2026-04-18

Company Type:
Trader
Location:
Hongkong, China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Melanotan 2: A Comprehensive Overview

    What is Melanotan 2?
    Melanotan 2 (MT-2) is a synthetic peptide analog of the naturally occurring hormone α-melanocyte-stimulating hormone (α-MSH). It is primarily used to stimulate melanin production in the skin, leading to enhanced pigmentation (tanning) and potential protection against ultraviolet (UV) radiation damage.

    Mechanism of Action
    Melanotan 2 works by binding to melanocortin receptors (MC1R and MC4R) in melanocytes, the cells responsible for producing melanin. This activation triggers increased synthesis of eumelanin (dark pigment) and, to a lesser extent, pheomelanin (light pigment), resulting in darker skin tone even with minimal sun exposure.

    Key Functions & Benefits

    • Enhanced Tanning: MT-2 induces pigmentation without prolonged UV exposure, reducing the risk of sunburn and cumulative skin damage.
    • Photoprotection: By boosting melanin levels, it may provide a natural defense against UV-induced DNA damage, lowering the risk of skin aging and certain skin conditions.
    • Appetite Suppression (Investigational): Early studies suggest MT-2 may influence appetite regulation via MC4R, though its use for weight management remains experimental.
    • Erectile Dysfunction (Off-Label): Some anecdotal reports indicate potential benefits for sexual function, but clinical evidence is limited.

    Safety & Usage
    Melanotan 2 is not approved by regulatory agencies (e.g., FDA, EMA) for human use and is classified as a research chemical. Potential side effects include:

    • Nausea and flushing (common with initial doses).
    • Darkening of moles or new freckles (requires monitoring).
    • Increased blood pressure or heart rate (rare but serious).
    • Systemic pigmentation changes, including darkening of gums or genital areas.

    Important Considerations

    • UV Exposure: MT-2 does not eliminate the need for sunscreen; UV protection remains essential.
    • Purity & Source: Illegally sold products may contain contaminants or incorrect dosages, posing health risks.
    • Long-Term Effects: Unknown due to limited clinical research.

    Regulatory Status
    In many countries, Melanotan 2 is banned for human consumption and is only legally available for laboratory research. Unauthorized use may result in legal consequences.

    Future Directions
    Research continues to explore MT-2’s potential in photodermatology and metabolic disorders, but its safety profile must be rigorously evaluated before widespread medical adoption.

    Disclaimer: This information is for educational purposes only. Consult a healthcare professional before considering any use of Melanotan 2.


    ECHEMI Editorial Reference

    Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is a peptide hormone used to promote tanning.

    Basic Info
    Product Name:

    Mt-2

    Other Name:

    melanotan-II;Melanotan II;MT-II;Melanotan (MT)-II;Melatonan;Melanotan II acetate salt;CHEMBL430239;(3S,6S,9R,12S,15S,23S)-12-((1H-imidazol-5-yl)methyl)-3-((1H-indol-3-yl)methyl)-15-((S)-2-acetamidohexanamido)-9-benzyl-6-(3-guanidinopropyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide;L-Lysinamide, N-acetyl-L-norleucyl-L-alpha-aspartyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, cyclic (2-7)-peptide

    CAS No.:

    121062-08-6

    Molecular Formula:

    C50H69N15O9

    InChIKeys:

    JDKLPDJLXHXHNV-MFVUMRCOSA-N

    Molecular Weight:

    1024.18

    Exact Mass:

    1023.540283

    EC Number:

    1308068-626-2

    UNII:

    UPF5CJ93X7

    DSSTox ID:

    DTXSID90153135

    Categories:

    Polypeptide

    Characteristics
    PSA:

    382.26000

    XLogP3:

    -1.27

    Appearance:

    white solid

    Density:

    1.4±0.1 g/cm3

    Refractive Index:

    1.683

    Water Solubility:

    H2O: 5 mg/mL, soluble

    Storage Conditions:

    −20°C

    Research
    Class:

    Synthetic cyclic heptapeptide / non-selective melanocortin receptor agonist

    Status:

    Research compound — NOT FDA approved. FDA issued warning letters. WADA banned substance.

    Mechanism:

    A synthetic cyclic heptapeptide (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂) analog of α-MSH. Melanotan II is a high-affinity non-selective agonist at MC1R, MC3R, MC4R, and MC5R. MC1R activation induces melanogenesis (skin darkening/tanning); MC4R activation affects sexual function, appetite suppression, and energy homeostasis. Carries significant safety risks including nausea, hypertension, and priapism.

    EC50 (Human Mc1r Ki):

    1.2 nM

    EC50 (Human Mc5r Ki):

    1.0 nM

    EC50 (Human Mc3r Ki):

    1.1 nM

    EC50 (Human Mc4r Ki):

    2.1 nM

    Source:

    Wikberg JES, et al. Pharmacol Res. 2000;42(5):393–420. PubChem CID 92432.DOI

    Clinical Development:

    NCT00005114

    References
    ChEMBL:

    CHEMBL363210

    PubChem:

    PubChem

    Disclaimer:

    Melanotan II is NOT FDA-approved. The FDA has issued multiple warning letters to companies illegally selling Melanotan II as an unapproved new drug. It is also listed on the WADA Prohibited List as a banned substance in sport. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

    Location:

    Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $50 million-$100 million

    Total Employees:

    51-100

    Year of Establishment:

    2012

    We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

    In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

    Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

    "Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

  • Inquiry History
    92 Inquiries
    Country Product Purchase Quantity Date Posted
    United Kingdom

    Mt-2

    1  Oct 28, 2026
    United Kingdom

    Mt-2

    5 MT Oct 22, 2026
    United Kingdom

    Mt-2

    5 MT Oct 21, 2026
    Tunisia

    Mt-2

    10 MG Oct 20, 2026
    United Kingdom

    Mt2

    100 MG Oct 19, 2026
    China

    Mt-2

    50 MG Oct 18, 2026
    China

    Mt-2

    21 MT Oct 17, 2026
    Romania

    Mt-2

    2 MT Oct 15, 2026
    Sweden

    Mt-2

    200 G Oct 8, 2026
    United Kingdom

    Melanotan II

    10 MG Sep 29, 2026
    France

    Mt-2

    200 MG Sep 26, 2026
    Netherlands

    Mt-2 ghk rt…

    1 MT Sep 23, 2026
    United Kingdom

    melanotan 2

    1 KG Sep 7, 2026
    Australia

    Melanotan 2

    10 PCS Sep 7, 2026
    United States

    Mt2

    5 G Aug 5, 2026
    United States

    Melanotan 2

    10 MG Jul 15, 2026
    Ireland

    MT2

    10 MG Jul 10, 2026
    United Kingdom

    Mt-2

    20 MT Jul 5, 2026
    United States

    Melanotan II

    10 MG Jul 4, 2026
    China

    MT-2

    1 MT Jun 30, 2026
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