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API Clindamycin HCl

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CAS No.:

21462-39-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2026-04-27

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Description

    Name

    Clindamycin HCl

    CAS number

    21462-39-5 (HCl)

    Description

    Clindamycin HCl is a ribosomal translocation and protein synthesis inhibitor that displays efficacy against MRSA. It is also occasionally used to treat Plasmodium. It has the same antibacterial spectrum as lincomycin, but the antibacterial activity is four to eight times stronger than that of lincomycin.

    Related CAS #

    21462-39-5 (HCl) 18323-44-9 (free) 24729-96-2 (phosphate) 58207-19-5 (HCl monohydrate) 25507-04-4 (palmitate HCl)

    Synonym

    Cleocin; Cleocin HCl; Clinsol; EC 244-398-6; EC2443986; EC-244-398-6; U 21251 F; U21251F; U-21251-F

    Appearance

    Solid powder

    Quality Standard

    USP, EP, BP, CP

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China


    Clindamycin HCl More Info

    1. Chemical and Physical Characteristics

    Clindamycin hydrochloride is a semi-synthetic lincosamide antibiotic, derived from lincomycin through chlorination. It appears as a white, hygroscopic crystalline powder with a melting point of 141-143°C. The compound is highly soluble in water, ethanol, methanol, and DMSO, making it suitable for various pharmaceutical formulations and laboratory applications.

    2. Key Specifications

    Molecular Formula: C₁₈H₃₃ClN₂O₅S·HCl (anhydrous) or C₁₈H₃₄Cl₂N₂O₅S (hydrochloride form).

    Molecular Weight: 461.44 g/mol.

    Purity: Typically >98% by HPLC, meeting USP or EP standards.

    Physical Form: White or almost white crystalline powder, hygroscopic in nature.

    3. Pharmacological Profile

    Clindamycin hydrochloride acts by binding to the 50S subunit of the bacterial ribosome, effectively inhibiting protein synthesis. This mechanism confers a broad spectrum of activity, particularly against Gram-positive bacteria and anaerobes. It is commonly used to treat infections caused by Staphylococcus aureus, Streptococcus pneumoniae, and various anaerobic pathogens.

    4. Storage and Handling

    The product should be stored desiccated at -20°C to maintain stability over extended periods. In solution, it remains stable when stored at -80°C, ensuring its efficacy for research and clinical applications.

    5. Regulatory and Market Information

    Clindamycin hydrochloride is classified as a prescription-only medicine (S4 in Australia) and is widely marketed under various brand names, including Cleocin and Dalacin. It is available in multiple dosage forms, such as capsules (e.g., 75 mg, 150 mg, 300 mg) for oral administration and as a sterile solution for injection.

     

    Shop API Clindamycin HCl-Detailed Image 1

    ECHEMI Editorial Reference
    Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.

    Basic Info
    Product Name:

    Clindamycin hydrochloride

    Other Name:

    L-threo-α-D-galacto-Octopyranoside,methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-,hydrochloride (1:1);L-threo-α-D-galacto-Octopyranoside,methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-,monohydrochloride,(2S-trans)-;L-threo-α-D-galacto-Octopyranoside,methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-,monohydrochloride,trans- α-;L-threo-α-D-galacto-Octopyranoside,methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-,monohydrochloride;Clindamycin hydrochloride;Clindomycin hydrochloride;7(S)-Chloro-7-deoxylincomycin hydrochloride;Clindimycin hydrochloride;7-Chloro-7-deoxylincomycin hydrochloride;Cleocin hydrochloride;Dalacina;Antirobe vet.;Clindavet;Clinacin;26884-28-6;32795-16-7

    CAS No.:

    21462-39-5

    Molecular Formula:

    C18H33ClN2O5S.ClH

    InChIKeys:

    InChIKey=AUODDLQVRAJAJM-XJQDNNTCSA-N

    Molecular Weight:

    461.44

    Exact Mass:

    460.156555

    EC Number:

    244-398-6

    HScode:

    29419000

    Categories:

    Antibiotics

    Characteristics
    PSA:

    128 Ų

    XLogP3:

    log Kow = 2.16

    Appearance:

    white crystalline powder

    Melting Point:

    144 °C

    Boiling Point:

    628.1°C at 760 mmHg

    Flash Point:

    333.6ºC

    Water Solubility:

    H2O: 50 mg/mL, clear, colorless

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    5.28X10-17 mm Hg at 25 °C (est)

    Specific rotation:

    Specific optical rotation = +214 deg at 25 °C/D (chloroform)

    Hazard Identification

    Classification of the substance or mixture

    Skin sensitization, Category 1

    Eye irritation, Category 2

    Acute toxicity - Category 4, Inhalation

    Specific target organ toxicity – single exposure, Category 3

    Reproductive toxicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H317 May cause an allergic skin reaction

    H319 Causes serious eye irritation

    H332 Harmful if inhaled

    H335 May cause respiratory irritation

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P264 Wash ... thoroughly after handling.

    P271 Use only outdoors or in a well-ventilated area.

    P203 Obtain, read and follow all safety instructions before use.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P321 Specific treatment (see ... on this label).

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P317 Get medical help.

    P319 Get medical help if you feel unwell.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

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