JI-101
Unit Price:
Get Latest Price
CAS No.:
900573-88-8
Content:
98%
Port:
Shang Hai
Packaging:
1g/bag-1kg/bag
Sample Available:
Yes
Price valid (until):
2026-04-30
Company Type:
Manufactory
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
15 days
Qualification:
Main Products:
SR17018
-
Product Details
-
Seller Information
-
DescriptionECHEMI Editorial ReferenceJI-101 has been used in trials studying the treatment of Cancer, Colon Cancer, Neuroendocrine, Ovarian Cancer, and Advanced Solid Tumors.|Angiogenesis Inhibitor JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRb), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities. Angiogenesis inhibitor JI-101 binds to and inhibits VEGFR2, PDGFRb and EphB4, which may inhibit tumor angiogenesis and, so, cellular proliferation in tumor cells overexpressing VEGFR2, PDGFRb and EphB4. The receptor tyrosine kinases VEGFR2, PDGFRb and EphB4 may be overexpressed in a number of different cancer cell types and may play crucial roles in tumor angiogenesis.Basic Info
-
Product Name:
JI-101
Other Name:JI-101;CGI 1842;1-[1-[(2-Aminopyridin-4-yl)methyl]-1H-indol-4-yl]-3-(5-bromo-2-methoxyphenyl)urea;CS-2268;JI101;JI 101;Urea, N-[1-[(2-amino-4-pyridinyl)methyl]-1H-indol-4-yl]-N'-(5-bromo-2-methoxyphenyl)-;Pazopanib Impurity 66
CAS No.:900573-88-8
Molecular Formula:C22H20BrN5O2
InChIKeys:ZXBFYBLSJMEBEP-UHFFFAOYSA-N
Molecular Weight:466.33
Exact Mass:465.08004
EC Number:604-604-1
UNII:980M4N37DH
NCI Thesaurus Code:C82413
Categories:
Characteristics-
PSA:
98.42000
XLogP3:5.09860
Density:1.50±0.1 g/cm3
Boiling Point:606.9±55.0 °C(Predicted)
PKA:13.25±0.70
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
SR17018
-
Location:
No. 8 Crown Road, Daguan District, Anqing City
-
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
15 days
-
Total Annual Revenue:
$2.5 million-$5 million
-
Total Employees:
11-50
-
Year of Establishment:
2017
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product
