 Home > Specialty Chemicals > 1-(6-(4-Fluorobenzyl)-5-(hydroxymethyl)-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-((2R,5R)-5-methyl-2-(((R)-3-methylmorpholino)methyl)piperazin-1-yl)ethan-1-one for Sale > ASTX660

ASTX660

Unit Price: Get Latest Price 

CAS No.:

1799328-86-1

Content:

98%

Port:

Shang Hai

Packaging:

1g/bag-1kg/bag

Sample Available:

Yes

Price valid (until):

2026-04-30

Contact Supplier

 Chat Now

Anqing Rongchuang Biotechnology Co., Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

SR17018

 Visit Store

Product Details
Seller Information

Description

Product Detail

Pls input...

Product Name: ASTX660	Other Name: ASTX660
CAS No: 1799328-86-1	Molecular Formula: C30H42FN5O3
Exact Mass:	Molecular Weight: 539.68

ECHEMI Editorial Reference

ASTX660 is under investigation in clinical trial NCT02503423 (Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas).|Tolinapant is an orally bioavailable, non-peptidomimetic antagonist of both X chromosome-linked inhibitor of apoptosis protein (XIAP) and cellular IAP 1 (cIAP1), with potential antineoplastic and pro-apoptotic activities. Upon administration, tolinapant selectively binds to and inhibits the activity of XIAP and cIAP1. This restores and promotes the induction of apoptotic signaling pathways in cancer cells, and inactivates the nuclear factor-kappa B (NF-kB)-mediated survival pathway. XIAP and cIAP1 are overexpressed by many cancer cell types and suppress apoptosis by inhibiting the activity of certain caspases; they promote both cancer cell survival and chemotherapy resistance.

Basic Info

Product Name:

1-(6-(4-Fluorobenzyl)-5-(hydroxymethyl)-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-((2R,5R)-5-methyl-2-(((R)-3-methylmorpholino)methyl)piperazin-1-yl)ethan-1-one

Other Name:

ASTX660;1799328-86-1;ASTX-660;UNII-2LHZ9ZC3YO;2LHZ9ZC3YO;CHEMBL4173974;1799328-86-1 (free base);1-(6-(4-fluorobenzyl)-5-(hydroxymethyl)-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-((2R,5R)-5-methyl-2-(((R)-3-methylmorpholino)methyl)piperazin-1-yl)ethan-1-one;Tolinapant;ASTX 660

CAS No.:

1799328-86-1

Molecular Formula:

C30H42FN5O3

InChIKeys:

YCXOHEXZVKOGEV-DNRQZRRGSA-N

Molecular Weight:

539.7

Exact Mass:

539.32716838

UNII:

2LHZ9ZC3YO

NCI Thesaurus Code:

C123913

Categories:

Seller Information

Business Type:
Manufactory

Main Products:
SR17018

Location:
No. 8 Crown Road, Daguan District, Anqing City

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2017
Country Product Purchase Quantity Date Posted

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
MK-8353 CAS 1799328-86-1 White to Off White Solid 98 Percent Purity ERK1 ERK2 Inhibitor for Oncology and MAPK Pathway Research	Reagent Grade/99	$5000-6000/G FOB	Jinan topfull chemical co.,ltd	Inquiry
ASTX660	Industrial Grade/99		Shaanxi Dideu Medichem Co. Ltd	Inquiry

ASTX660

Product Details

Seller Information

More Choices Find All Products for Sale 

Related Searches

More from this Seller