Hot Selling Raw Material Cimetidine 99% powder 51481-61-9 Factory Supply High Qulity
TDS 1 Inquiries
51481-61-9
Pharmaceutical Grade
99%
XI'AN
XAHNB
1kg/bag
2026-05-01
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceWhite Solid
Cimetidine appears as white crystals with a slight sulfur-mercaptan odor. (NTP, 1992)|Solid
Cimetidine appears as white crystals with a slight sulfur-mercaptan odor. (NTP, 1992)|Cimetidine is a member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach. It has a role as a H2-receptor antagonist, a P450 inhibitor, an anti-ulcer drug, an analgesic and an adjuvant. It is a member of guanidines, a member of imidazoles, an aliphatic sulfide and a nitrile.|A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.|Cimetidine is a Histamine-2 Receptor Antagonist. The mechanism of action of cimetidine is as a Histamine H2 Receptor Antagonist.|Cimetidine is a histamine type 2 receptor antagonist (H2 blocker) which is widely used for treatment of acid-peptic disease and heartburn. Cimetidine has been linked to rare instances of clinically apparent acute liver injury.|Cimetidine is a histamine H(2)-receptor antagonist. Enhancing anti-tumor cell-mediated responses, cimetidine blocks histamine's ability to stimulate suppressor T lymphocyte activity and to inhibit natural killer (NK) cell activity and interleukin-2 production. Cimetidine also may inhibit tumor growth by suppressing histamine's growth-factor activity and blocking histamine-induced stimulation of vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor. (NCI04)|A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.CertificatesBasic Info-
Product Name:
Cimetidine
Other Name:Guanidine,N-cyano-N′′-methyl-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-;Guanidine,N-cyano-N′-methyl-N′′-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-;N-Cyano-N′′-methyl-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine;Cimetidine;N-Cyano-N′-methyl-N′′-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidine;Tagamet;Eureceptor;Histodil;Biomet;Ulcimet;Cimetag;Dyspamet;Acinil;Tametin;Peptol;Ulcofalk;Cimal;Tratul;Ulcerfen;Ulhys;Ulcomedina;Edalene;Cimetum;SKF 92334;Ulcedin;Ulcedine;Gastromet;Ulcomet;Acibilin;NSC 335308;Ulcerex;Tamagret;Fremet;Tagamet HB 200;Tagamet HB;1-Cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine;79347-40-3
CAS No.:51481-61-9
Molecular Formula:C10H16N6S
InChIKeys:InChIKey=AQIXAKUUQRKLND-UHFFFAOYSA-N
Molecular Weight:252.34
Exact Mass:252.34
EC Number:257-232-2
UNII:80061L1WGD
NSC Number:757428|335308
DSSTox ID:DTXSID4020329
NCI Thesaurus Code:C374
Color/Form:Crystals
ATC Code:A - Alimentary tract and metabolism
HScode:29339900
Categories:
Characteristics-
PSA:
114
XLogP3:1
Appearance:Cimetidine appears as white crystals with a slight sulfur-mercaptan odor. (NTP, 1992)
Density:1.2583 (rough estimate)
Melting Point:141-143 °C
Boiling Point:488ºC at 760 mmHg
Flash Point:248.9ºC
Water Solubility:H2O: 0.5 g/100 mL at 20 ºC
Storage Conditions:2-8°C
Toxicity:LD50 in mice, rats (mg/kg): 2600, 5000 orally; 150, 106 i.v.; 470, 650 i.p. (Brimblecombe)
Odor:Unpleasant odor
Taste:Bitter taste
PKA:6.8None
Dissociation Constants:6.8|pKa= 6.8
Collision Cross Section:156.5 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|155.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Air and Water Reactions:Slightly water soluble.
Reactive Group:Amines, Phosphines, and Pyridines
Hazard IdentificationClassification of the substance or mixture
Serious eye damage, Category 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H318 Causes serious eye damage
Precautionary statement(s) Prevention P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Preserve in tight, light resistant containers at controlled room temperatures.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China
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Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2017
Company Certificates-
ISO
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ISO
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
India
CIMETIDINE
10 MT Feb 4, 2025 Post an enquiry for this product
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