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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Retatrutide for Sale > Factory price Retatrutide Top Fat Burning Peptides Therapy Lyophilized 5mg 10mg/Vial Peptides Powder GLP-1 Retatrutide 2381089-83-2
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Factory price Retatrutide Top Fat Burning Peptides Therapy Lyophilized 5mg 10mg/Vial Peptides Powder GLP-1 Retatrutide 2381089-83-2

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Unit Price:

$100-110/MT FOB

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CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Guangdong

Brand:

zwxs

Packaging:

10mg/vial,10vials/box

Price valid (until):

2027-09-29

Company Type:
Trader
Location:
China
Qualification:
Main Products:

peptides

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Name:Kate

    Whatsapp:+86 18562300759

    Email Address:zwxs2@zwxstech.com

    We have good product quality and after-sales service, come and buy from me~

    Retatrutide (retatrutide/retatrutide) is an innovative therapeutic drug. The following is a detailed introduction to it:

    English name: Retatrutide
    Article Title: Retarglutide/Rataglutide
    CAS number: 2381089-83-2
    Drug type: glucose-dependent insulinotropic polypeptide (GIP)/glucagon-like peptide 1 (GLP-1)/glucagon (GCG) triple receptor agonist

    Retatrutide is a unique triple receptor agonist that can simultaneously activate the glucose-dependent insulinotropic polypeptide receptor (GIPR), the glucagon-like peptide-1 receptor (GLP-1R), and the glucagon receptor (GCGR).

    GLP-1R agonism: After stimulating GLP-1R, it can promote insulin secretion and inhibit glucagon release, thereby lowering blood sugar levels. It can also delay gastric emptying, allowing users to feel full and reduce appetite.

    GIPR agonism: Activating GIPR can enhance the secretion of insulin and further help lower blood sugar.

    GCGR agonism: The agonistic effect on GCGR can promote fat decomposition and energy metabolism, which helps achieve weight loss goals. This multiple mechanism of action works together to make Retatrutide show great potential in weight management, blood sugar control, and overall metabolic health regulation.

    Items Specifications
    Product Name Retatrutide
    Other Name LY3298176
    Appearance White power
    Specification 5mg 10mg 15mg 20mg 30mg
    Purity >99%

    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 1


     

    Mechanism of action


    Mechanism of action

    Retatrutide exerts multiple regulatory effects by simultaneously activating three receptors: GIP, GLP-1 and GCG:
    Regulate blood sugar: Improve glucose tolerance and help patients with type 2 diabetes lower blood sugar.
    Slows gastric emptying: By acting on the gastrointestinal tract, it slows down the passage of food through the digestive tract.
    Reduces appetite: Acts on receptors in the brain to reduce people's desire for food, thereby aiding weight loss.

    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 2 Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 3


     

      Clinical trial results  

     


    Clinical trial results

    Weight loss effect: In phase 2 clinical trials, Retatrutide demonstrated significant weight loss effects. Obese patients lost more than 24% of their body weight after 48 weeks of treatment with Retatrutide. Among them, patients taking 8mg and 12mg doses lost at least 5% of their weight, and the weight loss effect of the high-dose group (12mg) was more significant.
    Hypoglycemic effect: After 6 months of treatment with different doses of Retatrutide in patients with type 2 diabetes, glycated hemoglobin (HbA1c) decreased by 1.3%\~2.0%.
    Safety: The safety and tolerability profile of Retatrutide is similar to other receptor agonists. The most common adverse reactions are gastrointestinal reactions, such as nausea, diarrhea, vomiting and constipation, mostly mild to moderate. In addition, some patients experience symptoms of increased heart rate, but this usually resolves after 24 weeks.

    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 4 Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 5


     

       Product Detail  

     


    Scope of application
    Obesity treatment: As an auxiliary treatment to diet control and exercise, it is used for long-term weight management in adults who are obese or overweight and have at least one weight-related comorbidity.
    Type 2 diabetes treatment: Helps patients with type 2 diabetes lower blood sugar and lose weight at the same time.

    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 6


     

    Storage conditions

     


    Storage conditions
    Low temperature, non-hazardous chemical shipments.
    Packed to the nearest milligram upon request.
    It is recommended to store sealed and away from light at 2~8°C, and refrigerated at -15~0°C for long-term storage.



    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 7 Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 8


     

      Product packaging

     


    5mg/vial,10vials/box;

    10mg/vial,10vials/box;

    15mg/vial,10vials/box;

    20mg/vial,10vials/box;

    30mg/vial,10vials/box;




    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 9

    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 10

      logistics  


    Customers can specify express delivery, such as: UPS/DHL, etc. (Default express delivery: our cooperative logistics company)

    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 11


     

    Company Profile

     


    Jinan Zhiwen Technology Co., Ltd.,  located in Shandong  Province, is a high-tech enterprise focusing on the research, development and production of peptide products. The company was established in recent years and is committed to applying advanced biotechnology to the health industry to meet the market's demand for high-quality, high-efficiency peptide products.
    As a leading peptide manufacturer,Jinan Zhiwen Technology has a R&D team composed of senior scientists and engineers, which continues to explore and innovate, and is committed to developing safer, more effective, and more market-competitive peptide products. The company's main products cover but are not limited to pharmaceutical grade, food grade and cosmetic grade and other fields, and are widely used in many aspects such as health care, disease prevention, beauty and skin care.

    In terms of production technology,Jinan Zhiwen Technology adopts internationally advanced production equipment and technology to ensure that every aspect of the product, from raw material selection, production and processing to finished product packaging, strictly follows relevant national standards and specifications to ensure product quality and safety. At the same time, the company has also established a complete quality management system and after-sales service system to provide customers with all-round, one-stop service support.
    Jinan Zhiwen Technology adheres to the corporate philosophy of "technology leads health, quality creates the future" and always adheres to the development path of people-oriented and technological innovation. The company not only focuses on product quality and innovation, but also actively fulfills its social responsibilities and is committed to promoting the development and progress of the health industry.

    In the future, Jinan Zhiwen Technology Co., Ltd. will continue to delve into the field of peptide product research and development, continue to explore and make breakthroughs, and strive to become a leader in the global peptide industry and make greater contributions to human health.

    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 12

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      Why choose us?

    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 14

    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 15

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    Shop high purity Peptide Cagrilintide Retatrutide Epithalon Lyophilized Powder for Weight Loss Peptide factory price-Detailed Image 18

    ECHEMI Editorial Reference
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.

    Certificates
    • Factory price Retatrutide Top Fat Burning Peptides Therapy Lyophilized 5mg 10mg/Vial Peptides Powder GLP-1 Retatrutide 2381089-83-2 Certificates 1 TDS

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    Molecular Formula:

    C221H342N46O68

    Molecular Weight:

    4731.33

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    peptides

    Location:

    No. 41-9, Fenghuangshan Road, Beiyuan Street, Tianqiao District, Jinan City, Shandong Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    3

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2026

    Jinan Zhiwen Technology Co., Ltd. is a professional manufacturer and supplier of pharmaceutical raw materials, peptide compounds and fine chemicals. We own standardized laboratories and complete quality inspection procedures, strictly testing every batch for purity and consistency. Our product portfolio covers hot‑sale peptide APIs, chemical intermediates for biomedical research. Serving clients worldwide, we provide custom synthesis, sample support, flexible order volumes and end‑to‑end supply‑chain solutions. Committed to quality‑first principle, we strive to become your long‑term and dependable partner for biochemical raw‑material procurement.


    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    Peak season lead time: within 3 Workday; Off season lead time: within 1 Workday

  • Inquiry History
    6778 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Retatrutide 2381089-83-2

    3 MT Mar 28, 2026
    United Kingdom

    Retatrutide - 2381089-83-2

    1 G Feb 10, 2026
    United States

    Retatrutide CAS 2381089-83-2 10mg vial

    20 MT Mar 7, 2026
    United States

    Factory Retatrutide API 99% Purity CAS 2381089-83-2

    5 KG Nov 10, 2025
    United Kingdom

    Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA

    1 MT Mar 22, 2026
    United States

    2381089-83-2

    100 G Jul 14, 2026
    United States

    2381089-83-2

    100 G Feb 24, 2026
    United States

    2381089-83-2

    100 MT Dec 9, 2023
    United States

    Retatrutide 2381089-83-2

    200 MG May 16, 2026
    United Kingdom

    2381089-83-2 retatrutide

    300 MG Feb 13, 2026
    United States

    Retatrutide 2381089-83-2 wholesale

    500 MT Nov 3, 2023
    United States

    Retatrutide CAS 2381089-83-2 99%

    10 PCS Feb 21, 2026
    Poland

    CAS 2381089-83-2 (Custom Peptide)

    40 MT Apr 10, 2026
    Austria

    Peptide Retatruide CAS 2381089-83-2

    100 MT Apr 4, 2026
    Austria

    Retatrutide CAS 2381089-83-2 10mg vial

    20 PCS Feb 10, 2026
    United States

    Tirzepatide 99.9% Liquid 2381089-83-2 TeruiOP

    1 MT Sep 6, 2023
    United States

    Retatrutide/LY3437943/GIPR/GLP-1R 98% Powder 2381089-83-2 Senwayer

    1 G Sep 3, 2023
    United States

    GLP-1 / GIP Retatrutide cas 2381089-83-2

    1 MT Oct 16, 2024
    United States

    Retatrutide 99% High Quality CAS 2381089-83-2

    1 G Jan 23, 2026
    United States

    Injection Peptide Tirzepatide/Retatrutide/ Semaglutide Peptides CAS 2381089-83-2

    10  Oct 21, 2023
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