Nootropics Powder 99% TAK-653 for Sale CAS 1358751-06-0 TAK-653 Raw Powder

Osavampator (TAK-653, NBI-1065845) is an experimental, orally active AMPA receptor positive allosteric modulator (PAM) under development by Takeda (and licensed to Neurocrine Biosciences) for treating major depressive disorder (MDD) and treatment-resistant depression. It acts by strengthening AMPA receptor-mediated synaptic signaling and has shown potential to improve cognitive function and reverse depressive-like symptoms.

• 1. Mechanism of Action: As a positive allosteric modulator, it selectively potentiates AMPA receptor activity in a glutamate-dependent manner, boosting BDNF protein levels and strengthening neuronal connections.
• 2. Antidepressant Effects: Studies indicate that sub-chronic administration of TAK-653 reduces depression-like behaviors in animal models.
• 3. Cognitive Enhancement: Research suggests it improves cognitive functions, specifically working memory and visual learning, as observed in studies.
• 4. Clinical Development: It is being evaluated to treat patients with Major Depressive Disorder (MDD) and has been tested for safety, tolerability, and pharmacokinetics in healthy volunteers.
• 5. Pharmacodynamic Effects: In studies, TAK-653 showed potential psychostimulant-like effects, increasing saccadic peak velocity (SPV) and influencing visual attention tests.
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Packing: 

1. Weight <1kg ---- Fluorinated bottle 

2. 25kg ---- Plastic bucket

3. 180- 200kg ---- Drum

P.S.: we accept packaging customization.

Delivery:  

We have large quantity raw powder in stock, normally could ship out within 3 working days. 

For rush delivery, please contact our sales team for particular arrangement.

Shipping:

We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.

Shipping details & shipping documents will be provided and sent to customers as long as it is ready.

We keep tracking the shippment until clients well received.

After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.

Natrue is a high-end brand company focusing on the biomedical industry and integrating R&D, production and sales. It has an independent R&D center, advanced laboratory equipment and a professional R&D team, a GMP standard production workshop, a complete set of internationally advanced assembly line equipment, a preparation workshop with a cleanliness level of 100,000, as well as sophisticated testing instruments and scientific testing methods, providing solid technical support for the production of high-quality products. Through long-term R&D, production, and sales practices, it has formed its own unique product line, providing users with products of reliable quality at highly affordable prices. We strictly control quality, ensure the stability of product quality in all aspects, and win the trust of customers with high quality and high-level development.

Our team of experienced professionals is committed to delivering innovative solutions and exceptional customer service. We work closely with our clients to understand their unique needs and develop customized products to meet their specific requirements. With a state-of-the-art manufacturing facility and strict quality control measures, we ensure that our products meet the highest standards of safety and purity.

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FAQ

Q1: When will the product be shipped after payment?

  ---We are committed to the same day shipping.

Q2. How does your factory control quality?

All the raw material purchasing and production quality control are strictly following the ISO9001: 2008 management system. Besides, the full-featured detection equipment and GMP quality management system provided the strongest guarantee for a high-quality product.

Q3: How long will it take to receive the parcel?

   --3 days for the US market; 4-6 days for the others.

Q4: What can I do if I don't have the ability to clear the custom?

   --We got experience after doing export for many years, so don't worry we can handle that.

Q5: What about after-sale service?

 ---We promise to reissue free of charge if there is any problem.

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