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Home > Biochemical Engineering > Inhibitors > Mavacamten for Sale > Mavacamten CAS 1642288-47-8 lab use
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Mavacamten CAS 1642288-47-8 lab use

10 Inquiries

Unit Price: Get Latest Price
CAS No.:

1642288-47-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

/

Packaging:

bag

Price valid (until):

2026-05-08

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Mavaketene (trade name Camzyos) is a small molecule myosin modulator used to treat adult patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM). oHCM is a monogenic cardiovascular disease caused by mutations in sarcoproteins, particularly myosin.

    Mavakitai reduces excessive cardiac contraction by decreasing actin-myosin cross-bridge formation and inhibiting cardiac myosin ATPase activity. Both of these effects reduce contractility by modulating myosin function.


    1. Consignee name: Mr.lucas
    2. Phone/what3pp:86 15053178817
    3. E mail:lucas@tf-chemi.com

    ECHEMI Editorial Reference
    Mavacamten is under investigation in clinical trial NCT03442764 (A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)).
    Mavacamten(MYK-461)is a first-in-class allosteric inhibitor of cardiac myosin that promises to provide clinicians with targeted therapy for these patients. It is a mechanistically novel small molecule that acts on the sarcolemma to specifically inhibit contractility and has been proposed as a treatment for HCM.

    Basic Info
    Product Name:

    Mavacamten

    Other Name:

    MYK-461 (SAR-439152);SAR 439152;SAR439152;SAR-439152;SAR-439152; SAR 439152; SAR439152; MYK-461; MYK 461; MYK461; MAVACAMTEN;MYK-461 - Mavacamten | SAR439152;Mavacamten (MYK-461;6-([(1S)-1-phenylethyl]amino)-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

    CAS No.:

    1642288-47-8

    Molecular Formula:

    C15H19N3O2

    InChIKeys:

    RLCLASQCAPXVLM-NSHDSACASA-N

    Molecular Weight:

    273.33

    Exact Mass:

    273.147726857

    EC Number:

    213-161-7

    UNII:

    QX45B99R3J

    Color/Form:

    White to off-white

    Categories:

    Inhibitors

    Characteristics
    Density:

    1.19±0.1 g/cm3(Predicted)

    PKA:

    8.83±0.40(Predicted)

    Critical Temperature & Pressure:

    Storage temp. -20°C

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    10 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Mavacamten

    10.00 MT Jan 22, 2024
    India

    MAVACAMTEN API POWDER

    25.00 KG Feb 29, 2024
    India

    MAVACAMTEN

    25 KG Feb 28, 2024
    Russia

    Mavacamten

    100 G Mar 31, 2025
    Australia

    Mavacamten

    1 MT May 15, 2025
    India

    Mavacamten

    1.00 KG Mar 7, 2024
    India

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