Product Name: MGF (Mechano Growth Factor, IGF-1Ec)
Available Specifications: 2mg/vial, 5mg/vial
Form: High-purity lyophilized (freeze-dried) white powder
Product Overview
MGF (Mechano Growth Factor) is a naturally occurring, alternatively spliced isoform of Insulin-Like Growth Factor-1 (IGF-1), known as IGF-1Ec in human biology. It is a specialized peptide that is locally expressed in muscle tissues in direct response to mechanical stress, intense exercise, or cellular damage. This research-grade peptide is designed to support scientific investigations into muscle regeneration, tissue repair, cellular recovery, and related biological processes.
Key Features & Advantages
- Ultra-High Purity: Manufactured under strict quality control protocols, with purity verified at ≥98% by High-Performance Liquid Chromatography (HPLC) analysis.
- Synthetic & Stable: Produced via solid-phase peptide synthesis to ensure a consistent, contaminant-free product, presented as a stable lyophilized powder.
- Research-Grade Standard: Formulated exclusively for in vitro, preclinical, and laboratory research applications.
- Consistent Quality: Each batch is accompanied by a Certificate of Analysis (CoA) confirming purity, identity, and composition.
Core Research Applications & Potential Benefits
- Muscle Satellite Cell Activation: Supports research into the activation and proliferation of quiescent muscle satellite cells, which are essential for muscle fiber repair and growth.
- Tissue Regeneration Studies: Serves as a critical tool for investigating muscle tissue repair, hypertrophy, and recovery following mechanical stress or injury.
- Cellular Recovery Research: Aids studies on the body's natural anabolic response to muscle microdamage, focusing on protein synthesis and tissue adaptation.
- Age-Related Research: Used in investigations focused on maintaining muscle cell activity and supporting regenerative processes in age-related studies.
- Connective Tissue & Healing: Explored in research related to the repair and maintenance of tendons, ligaments, and other supportive tissuesPubMed.
Mechanism of Action
MGF functions by specifically targeting and activating muscle satellite cells—resident stem cells located between muscle fibers. Upon exposure, MGF initiates a biological cascade that prompts these cells to exit their dormant state, proliferate, and fuse with damaged or stressed muscle fibers. This process is fundamental to the natural repair and adaptive growth of muscle tissue, making MGF a key signaling molecule in the body's response to physical exertion. Unlike systemic IGF-1, MGF acts locally and is optimized for rapid, targeted tissue response.
Physical & Chemical Properties
- Appearance: White to off-white sterile lyophilized powder.
- Solubility: Highly soluble in sterile water or bacteriostatic saline at a concentration of ≥0.5 mg/mL, with optimal stability at pH 6.5–7.5.
- Storage Instructions:
- Lyophilized powder: Stable for 3–4 weeks at room temperature; long-term storage recommended at ≤-18°C in a desiccated environment.
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