Dimethyl sulfoxide(67-68-5)

Dimethyl sulfoxide

sulfinylbis (methane);DMSO;DIMETHYL SULFOXIDE;DIMETHYL SULPHOXIDE;DIMETHYLIS SULFOXIDUM;FEMA 3875;Methyl sulfoxide, extra pure, 99.85%;Methyl sulfoxide, for analysis ACS, 99.9+%

67-68-5

C2H6OS

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

78.13

506008

200-664-3

TSCA listed

clear colorless

29309070

Organosulfur Compounds

λ: 285 nm Amax: ≤0.20λ: 295 nm Amax: ≤0.20

Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

1.100 g/mL at 20 °C

18.4 °C

189 °C(lit.)

n20/D1.479(lit.)

Soluble in water, methanol, acetone, ether, benzene, chloroform.

0.42 mm Hg ( 20 °C)

2.7 (vs air)

DMSO is naturally released in the environment, primarily by the oxidation of dimethyl sulfide that is biologically produced in soil, water, and vegetation. It is produced by phytoplankton, and may be released during its production, transport, disposal, and use as a solvent, medicinal analgesic, and other uses.If released in water, it should disproportionate to dimethyl sulfide and dimethyl sulfone, and may be reduced by reducing agents that may occur in natural waters. In soil, DMSO is rapidly reduced to dimethyl sulfide. In the atmosphere, DMSO will exist primarily in the vapor phase, and will react with photochemically produced hydroxyl radicals with a half-life of w7 h. It also may be released during its production, transport, disposal, and use as a solvent and medical analgesic.A bioconcentration factor (BCF) of <1 was observed for dimethyl sulfoxide, using orange-red killifish (Oryzias latipes) which were exposed over an 8-week period. According to a classification scheme, this BCF suggests that bioconcentration in aquatic organisms is low.

Combustible when exposed to heat or flame (NFPA rating = 1). Carbon dioxide or dry chemical extinguishers should be used to fight DMSO fires.

Mild garlic odor

35(at 25℃)

9.8×102mol/(m3Pa) at 25℃, Burkholder et al. (2019)

Denser than water and miscible in water.

Dimethyl sulfoxide decomposes violently on contact with many acyl halides, aryl halides and related compounds such as phenyl and tolyl chloride, acetyl chloride, benzenesulfonyl chloride, benzoyl chloride, cyanuric chloride, phosphorus chloride, phosphorus oxychloride, and thionyl chloride [Chem. Eng. News 35(9):87 (1957)]. Reacts, possibly violently, with iodine pentafluoride [Chem. Eng. News 47(12):, 109(1969)]. Vacuum distillation from anhydrous magnesium perchlorate led to an explosion [MCA Case History 1187(1966)]. Violently reactive with fluorinating agents such as silver fluoride [Chem. Eng. News 44(24):7(1956)]. Can explode with sodium hydride [Chem. Eng. News 44(24):7(1966)]. Mixture with methyl bromide resulted in an explosion that shattered the apparatus [NFPA 491M, 1991]. Forms salts with perchloric acid that are explosive when dry [Chem. Abst. 44:p3935d (1950)]. Decomposes when heated above normal boiling point.

215 °C

Store at +5°C to +30°C.