 Home > Pharmaceutical Intermediates > Antidementia Agents > (1R,2S)-2-[[(2,4-Dimethyl-5-pyrimidinyl)oxy]methyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropanecarboxamide for Sale > Lemborexant CAS 1369764-02-2 White Raw Powder 99% Lemborexant

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Lemborexant CAS 1369764-02-2 White Raw Powder 99% Lemborexant

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CAS No.:

1369764-02-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

Packaging:

25kg drum

Sample Available:

Yes

Price valid (until):

2026-05-13

Contact Supplier

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HNB Biotech

Company Type:

Manufactory

Location:

China

Payment Terms:

L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

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Product Details
Seller Information
Inquiry History

Description

Product Detail

whasapp：+8615202961574
Email:gary@xahnb.com

Items	Standard		Test Results

Identification	A.H-NMR:Comply with the structure		Complies
	B.LC-MS:Comply with the structure		Complies
	C.The IR spectrum of sample should be identical with that of reference standard.		Complies
	D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.		Complies
Loss on drying %	≤2.0		0.19
Heavy metals ppm	≤10		<10
Moisture %	≤1.0		0.1
Sulphated ash %	≤0.5 determined on 1.0 g.		0.009
Residue on ignition %	≤0.1		0.03
Related Substances %	Unspecified impurities: for each impurity	≤0.10	<0.10
Related Substances %	Total Impurity	≤0.5	0.18
Purity %	≥99.0		99.7
Assay %	99.0 ~101.0 (anhydrous substance).		99.8
Storage	Preserve in well-closed, light-resistant and airtight containers.		Complies

Xran Harmonious Natural Bio- Technology Co., Ltd was founded in 2017, and located in Xlan International Logistics Industrial Zone, Xran City. ShaanxtProvince, China. Now it is the leading researcher and one of the biggest manufacturer in high technology APl area.

There are 8 experts in our research team. We insistin innovation and produce high quality products. And GMP standard workshop and complete stainlessextraction equipment.

We have 2 sales deparments over 20 people and sellour products allover the word. We also have strong professional research and developmentteamtalented personnel and completely equipped laboratoy for the quality controlling. Various Detection Device is equipped in HNB company, such as HPLCGC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on
HNB mainly engaged in export of products incuding,wthoutlimitation., pharmaceutical raw materials both for vet and human, also Vitamins, Amino Acidsminerals, peptides, plant extract, feed and food additives. Our company's business is based on Honest, Trustwortly, Constanty to Go Beyond andAchieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.
Passion to innovate, Power to deliver !

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Q1 Can i get some samples
A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2 How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T,or Paypal or Escrow(Alibaba).
Q3 How to confirm the Product Quality before placing orders
A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4 What's your MOQ
A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5 How about delivery leadtime
A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6 Is there a discount
A6 Different quantity has different discount.
Q7 How do you treat quality complaint
A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q8 How to contact us
A8 You can chat with us by Trademanager,MSN&Skype Online.
You can choose your interested products and send inquiry to us.
You can dial our telephone directly or send Email to us., you will get our reply.

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ECHEMI Editorial Reference

Lemborexant (E-2006) is a dual antagonist of the orexin OX1 and OX2 receptors which is under development for treatment of insomnia.
Lemborexant is a DEA Schedule IV controlled substance. Substances in the DEA Schedule IV have a low potential for abuse relative to substances in Schedule III.|Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. Recent research in the field of sleep disorders has revealed that insomnia is likely driven not by the inability of the brain to "switch on" sleep-related circuits, but rather an inability to "switch-off" wake-promoting circuits. Whereas historically popular pharmacologic treatments for insomnia (e.g. [zopiclone], [zolpidem], benzodiazepines) focus on enhancing sleep drive via modulation of GABA and melatonin receptors, lemborexant and other orexin antagonists (e.g. [suvorexant]) act to counteract inappropriate wakefulness. This novel mechanism of action offers potential advantages over classic hypnotic agents, including a more favorable adverse effect profile and potentially greater efficacy, and may signal the beginning of a new wave of treatment options for patients suffering from insomnia.|Lemborexant is an orexin receptor antagonist used for the treatment of insomnia and sleep disorders. Lemborexant therapy is associated with rare occurrence of transient serum enzyme elevations, but has not been implicated in cases of clinically apparent liver injury.

Certificates

Basic Info

Product Name:

(1R,2S)-2-[[(2,4-Dimethyl-5-pyrimidinyl)oxy]methyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropanecarboxamide

Other Name:

Cyclopropanecarboxamide,2-[[(2,4-dimethyl-5-pyrimidinyl)oxy]methyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)-,(1R,2S)-;(1R,2S)-2-[[(2,4-Dimethyl-5-pyrimidinyl)oxy]methyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropanecarboxamide;Lemborexant;E 2006;Dayvigo

CAS No.:

1369764-02-2

Molecular Formula:

C22H20F2N4O2

InChIKeys:

InChIKey=MUGXRYIUWFITCP-PGRDOPGGSA-N

Molecular Weight:

410.4166064

Exact Mass:

410.42

UNII:

0K5743G68X

DEA Code Number:

2245

Categories:

Antidementia Agents

Characteristics

PSA:

77.00000

XLogP3:

3.16

Density:

1.347±0.06 g/cm3(Predicted)

Boiling Point:

596.1±50.0 °C(Predicted)

Flash Point:

314.3±30.1 °C

Refractive Index:

1.619

See More (1R,2S)-2-[[(2,4-Dimethyl-5-pyrimidinyl)oxy]methyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropanecarboxamide Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More (1R,2S)-2-[[(2,4-Dimethyl-5-pyrimidinyl)oxy]methyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropanecarboxamide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China

Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2017

Company Certificates
- ISO
- ISO
Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian

International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the

leading researcher and one of the biggest manufacturer in high technology API area.

There are 8 experts in our research team. We insist in innovation and produce high quality

products. And GMP standard workshop and complete stainless extraction equipment.

We have 2 sales departments over 20 people and sell our products all over the world.

We also have strong professional research and development team, talented personnel and

completely equipped laboratory for the quality controlling. Various Detection Device is

equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto

titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

HNB mainly engaged in export of products including, without limitation, pharmaceutical raw

materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant

extract, feed and food additives.

Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and

Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends

from both home and abroad.

Passion to innovate, Power to deliver !

Inquiry History

20 Inquiries

Country	Product	Purchase Quantity	Date Posted
Germany	(1R,2S)-2-[[(2,4-Dimethyl-5-pyrimidinyl)oxy]methyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropanecarboxamide	1 MT	Oct 24, 2026
Austria	(1R,2S)-2-[[(2,4-Dimethyl-5-pyrimidinyl)oxy]methyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropanecarboxamide	20 G	Oct 15, 2026
Sweden	Lemborexant	20 G	Oct 10, 2026
United States	Lemborexant	10 G	Sep 17, 2026
United States	(1R,2S)-2-[[(2,4-Dimethyl-5-pyrimidinyl)oxy]methyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropanecarboxamide	100 G	Sep 16, 2026
Germany	Lemborexant	1 G	Sep 8, 2026
Paraguay	Lemborexant	20 G	Aug 25, 2026
Paraguay	Lemborexant API	2 KG	Aug 25, 2026
United States	Dihexa, KY19382, WAY-262611, WAY-316606, 7,8-Dihydroxyflavone, Lemborexant	1 G	Aug 19, 2026
France	Lemborexant	1 G	Aug 5, 2026
France	Lemborexant	1 G	Aug 4, 2026
United States	Lemborexant	1 G	Jul 27, 2026
Italy	Lemborexant	1 G	Jun 10, 2026
Italy	Lemborexant	1 G	May 3, 2026
United States	Lemborexant	1 KG	Apr 25, 2026
Hungary	Lemborexant	1 G	Apr 12, 2026
Hungary	Lemborexant	10 G	Mar 5, 2026
Pakistan	Hira	50 G	Sep 29, 2025
China	LEMBOREXANT	5 G	Sep 7, 2025
India	Lemborexant 98℅	10 G	Apr 25, 2024

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