Dodecyl Gallate is a long-chain alkyl gallate and phenolic antioxidant commonly used in food-related antioxidant systems, cosmetic formulations, pharmaceutical research, chemical synthesis, and specialty formulations. It is valued for its gallic acid ester structure, lipophilic character, and suitability for formulations requiring oxidation-control support.
Dodecyl Gallate, also known as Lauryl Gallate or dodecyl 3,4,5-trihydroxybenzoate, belongs to the gallate ester family. Compared with shorter-chain gallates, its longer dodecyl chain provides greater fat solubility, making it especially relevant for oil-based, lipid-containing, and specialty antioxidant systems.
Key Product Information
Attribute | Description |
Product Name | Dodecyl Gallate |
Chemical Name | Dodecyl 3,4,5-trihydroxybenzoate |
Synonyms | Lauryl Gallate, Gallic acid dodecyl ester, Dodecyl 3,4,5-trihydroxybenzoate |
CAS Number | 1166-52-5 |
EC Number | 214-620-6 |
Molecular Formula | C19H30O5 |
Molecular Weight | 338.44 g/mol |
Appearance | White to off-white crystalline powder, depending on specification |
Main Components | Dodecyl gallate |
Main Function | Phenolic antioxidant, stabilizing agent, formulation ingredient, chemical intermediate |
Typical Use Areas | Food-related antioxidant systems, cosmetics, personal care, pharmaceutical research, chemical synthesis, analytical standards, and specialty formulations |
PubChem identifies Dodecyl Gallate as a gallate ester with molecular formula C19H30O5. Sigma-Aldrich lists Dodecyl Gallate, also known as Lauryl Gallate, under CAS 1166-52-5, and lists the EC number as 214-620-6.
Key Features
Feature | Benefit |
Long-chain gallate ester structure | Provides antioxidant functionality with improved fat-solubility characteristics |
Phenolic antioxidant profile | Supports oxidation-control and stabilization concepts |
Lipophilic character | Suitable for oil-based, lipid-containing, and fat-soluble formulation systems |
White to off-white powder form | Convenient for premixes, dry blends, and laboratory use |
Versatile application potential | Suitable for food-related research, cosmetics, specialty chemicals, and R&D |
Customizable quality options | Can be supplied according to purity, particle size, packaging, and customer requirements |
Typical Applications
Food-Related Antioxidant Systems
Dodecyl Gallate is commonly associated with antioxidant applications in food-related systems, particularly where oxidative stability of oils, fats, lipid ingredients, or fat-containing formulations is important. It may be evaluated for use in oil-based systems, fat-rich formulations, and specialty antioxidant blends. Any commercial use in food or beverage products should comply with local food additive regulations, approved use categories, dosage limits, labeling requirements, and product-grade standards.
Cosmetics and Personal Care
Dodecyl Gallate can be used in cosmetic and personal care formulations where antioxidant protection and formulation stabilization are desired. Its lipophilic profile makes it suitable for creams, lotions, balms, oils, emulsions, serums, masks, and other skincare or personal care systems containing oils or oxidation-sensitive ingredients.
Antioxidant and Stabilization Systems
Because Dodecyl Gallate contains multiple phenolic hydroxyl groups and a long alkyl chain, it is suitable for antioxidant-positioned systems requiring both phenolic activity and oil-phase compatibility. It may help support the stability of formulations containing oils, lipids, fragrances, fat-soluble actives, or other oxidation-sensitive components.
Chemical Synthesis and Research
Dodecyl Gallate is suitable for chemical research, synthesis, and analytical applications. It may be used as a phenolic building block, gallate ester reference compound, antioxidant model compound, or intermediate in specialty chemical development.
Pharmaceutical and Nutraceutical Research
Dodecyl Gallate may be used in pharmaceutical, nutraceutical, and biological research involving gallate esters, phenolic antioxidants, lipid-soluble compounds, and structure-function studies. Final commercial use in health-related products should be supported by appropriate regulatory review, safety evaluation, purity control, and product documentation.
Formulation Benefits
Dodecyl Gallate provides a useful combination of phenolic antioxidant functionality, long-chain alkyl gallate chemistry, and oil-phase compatibility. It is especially suitable for:
Food-related antioxidant systems involving oils, fats, or lipid-based formulations.
Cosmetic and personal care products requiring antioxidant-positioned ingredients.
Oil-based and emulsion systems requiring improved antioxidant compatibility.
Specialty formulations where oxidation control and stability support are desired.
Research and development involving gallate esters and phenolic antioxidants.
Chemical synthesis projects requiring a dodecyl gallate intermediate or reference compound.
Laboratory antioxidant studies and analytical quality-control applications.
Regulatory Note
The permitted use of Dodecyl Gallate depends on the destination market, product grade, purity, manufacturing process, intended application, and final product claims. For food, supplement, cosmetic, feed, pharmaceutical, or industrial use, customers should confirm local regulatory status, approved application scope, dosage limits, labeling requirements, safety data, and claims before commercialization.
The presence of a chemical name, CAS number, EC number, or database listing does not automatically mean that Dodecyl Gallate is approved for every use or every market. Customers should review the product COA, specification, Safety Data Sheet, and applicable local regulations before use.
Packaging and Storage
Store Dodecyl Gallate in a cool, dry, and well-ventilated area. Keep the container tightly closed after opening. Protect from moisture, heat, direct sunlight, strong oxidizing agents, strong bases, strong acids, and incompatible materials. Use appropriate protective equipment and follow the product label, COA, and Safety Data Sheet during handling.
Suggested Short Listing Copy
Dodecyl Gallate, also known as Lauryl Gallate, is a long-chain phenolic antioxidant and gallic acid ester used in food-related antioxidant systems, cosmetics, personal care, pharmaceutical research, chemical synthesis, and specialty formulations. With its gallate ester structure, lipophilic character, and oxidation-control potential, Dodecyl Gallate is suitable for manufacturers seeking a reliable ingredient for oil-based stabilization and specialty antioxidant applications.
Conclusion
Dodecyl Gallate is a versatile long-chain gallate ester for manufacturers and researchers seeking a phenolic antioxidant with strong oil-phase compatibility. Its antioxidant-positioned benefits, gallic acid ester structure, and lipophilic profile make it suitable for food-related antioxidant systems, cosmetics, personal care, chemical research, pharmaceutical research, and specialty formulation development. Overall, Dodecyl Gallate is a practical choice for product developers requiring a stable, functional, and high-quality antioxidant ingredient.
