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Anticancer API Erdafitinib CAS:1346242-81-6 99% Purity buy - large image1
Anticancer API Erdafitinib CAS:1346242-81-6 99% Purity buy - image1
Anticancer API Erdafitinib CAS:1346242-81-6 99% Purity buy - image2
Anticancer API Erdafitinib CAS:1346242-81-6 99% Purity buy - image3
Anticancer API Erdafitinib CAS:1346242-81-6 99% Purity buy - image4
Anticancer API Erdafitinib CAS:1346242-81-6 99% Purity buy - image5
Anticancer API Erdafitinib CAS:1346242-81-6 99% Purity buy - image6

Anticancer API Erdafitinib CAS:1346242-81-6 99% Purity

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Unit Price:

$110-130/G FOB

Get Latest Price
CAS No.:

1346242-81-6

Grade:

Pharmaceutical Grade

Content:

99.9%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1g/bag, 20g/bag, 50g/bags or other quantities

Price valid (until):

2026-11-30

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Name Erdafitinib
    CAS number 1346242-81-6
    Synonym JNJ-42756493;
    Erdafitinib;
    Erdafitinib(JNJ-42756493);
    890E37NHMV;
    DTXSID001027936
    Related APIs # Pemigatinib
    Infigratinib
    Futibatinib
    Rogaratinib
    Debio 1347
    AZD4547
    LY2874455
    TAS-120
    ARQ 087
    BGJ398
    Description Erdafitinib is a synthetic compound designed to interact with specific pathways within cells. It is primarily associated with the management of certain conditions that involve abnormal cell growth and division. Its development marks a significant step in precision medicine, where treatments are tailored based on the molecular characteristics of individual conditions.

    Description and Mechanism
    Erdafitinib belongs to a class of molecules known as kinase inhibitors. Kinases are enzymes that play a pivotal role in the signaling pathways that regulate cell functions, including division, growth, and survival. By inhibiting certain kinases, Erdafitinib can disrupt these pathways, thereby addressing abnormal cellular behaviors. This precision targeting is what makes kinase inhibitors such a valuable tool in managing conditions driven by these pathways.

    Medical Applications
    Erdafitinib is utilized in specific contexts, particularly where standard treatments are deemed less effective. It is considered in scenarios where cells exhibit particular genetic characteristics that make them susceptible to this type of intervention.

    Target Specificity: The compound is designed to be most effective in cases involving particular genetic alterations within cells. This specificity aims to maximize efficacy while minimizing effects on normal, healthy cells.
    Managing Resistance: It may be used in cases where other treatments have failed or when conditions have developed resistance to conventional therapies. By targeting specific pathways, Erdafitinib can offer alternative avenues to disrupt undesirable cell processes.
    Combination Approaches: Often, it can be used in conjunction with other compounds to enhance overall outcomes. These combination strategies can be tailored to the unique molecular profile of the condition being treated.

    Mechanism of Action
    Erdafitinib works by binding to and inhibiting specific kinase enzymes within the cell. This inhibition leads to the disruption of signaling pathways essential for cell proliferation and survival. The compound’s action is particularly focused on pathways that are aberrantly activated due to genetic mutations or alterations.

    Source and Development
    As a synthetic compound, Erdafitinib is produced through complex chemical processes in laboratory settings. Its development involves extensive research to ensure it effectively targets the desired enzymes without significantly affecting others. The synthesis process requires meticulous design and engineering, often involving numerous iterations and optimizations to refine its molecular structure for optimal activity.

    Safety and Efficacy
    Before becoming available for use, Erdafitinib undergoes rigorous testing:

    Preclinical Testing: Initial studies explore its activity in controlled environments, assessing its interaction with target enzymes and overall biological effects.
    Clinical Trials: Human trials are conducted in multiple phases to evaluate safety, optimal dosing, and effectiveness. These trials help understand how well the compound works in target populations and its potential side effects.

    Environmental and Ethical Considerations
    The production and use of Erdafitinib, like any synthetic compound, require adherence to strict regulatory standards to ensure safety and minimize environmental impact. Ethical standards also mandate rigorous testing to confirm the compound’s benefits outweigh any potential risks and that participants in trials provide informed consent.

    Conclusion
    Erdafitinib exemplifies the advances in molecularly targeted therapies, where treatments are customized based on individual genetic profiles. This represents a shift towards personalized medicine, offering hope for improved outcomes in managing complex conditions. The ongoing research and development of such compounds reflect a commitment to advancing medical science through innovation, with an emphasis on safety, efficacy, and environmental responsibility.

    As scientific understanding deepens, Erdafitinib and similar compounds may continue to evolve, offering even more refined and effective strategies for managing conditions that were previously difficult to treat. This progress underscores the dynamic nature of medical research and the continuous quest to improve health outcomes worldwide.

    Molecular Formula C 25 H 30 N 6 O 2
    Molecular Weight 446.5 g/mol
    Appearance White or almost white powder
    Quality Standard Enterprise standard; 99.99%
    Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
    Storage Condition Dry, dark and at 0-28 for short term (days to weeks) or 0-8 for long term (months to years).
    Shelf Life >2 years if stored properly
    Sample package Double plastic bags inside, fiber drum outside, any quantity available.
    Commercial package Aluminium Tin, Fiber drum
    Origin China


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    FAQ

    Q1. What is the Hyper chem payment term?
    T/T advance
    LC at sight
    DP at sight
    Trade assurance 
    Money gram 

     

    Q2. What is Hyper chem shipment policy?
    Our policy is to strive for the quickest shipment time possible, with ready stock sample shipment typically going out the same day that your order was placed. Your satisfaction is very important to us.
    For non-ready stock, please contact the Hyper Chem sales team to negotiate.

     

    Q3. What hyper chem will provide after shipment?
    For sample orders: 
    After shipment is done, an timely email including:

    Track details (Fedex /TNT/DHL/EMS Track number)

    Package photo

    COA, MSDS, etc 

    Dispatch date & Estimated arriving time

    Shipping invoice

    For commercial orders
    A full set of shipment documents as well as package photos can be provided
    in scan-copy and original, to help customers complete the customs clearance process.

     

    Q4. What is Hyper Chem shipment term?

    By Express   
    DHL  FedEx  TNT  EMS                               
    Fast:5 days around                             
    High cost, door to door service

    By Air                                         
    Suitable for more than 50kg 
    Fast :3-7 days Hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Slow:7-45 days, Low cost, port to port, professional broker needed 
    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

     

    Q5. Does hyper chem provide a shipment return policy?
    Yes, we have.
    Return Policy: At Hyper chem, your satisfaction is guaranteed. If you are dissatisfied for any reason with a product, please send back the unused portion along with your packing slip and a brief note on why you were dissatisfied  within 45 days of purchase for a full refund to:

     

    Q6. What is hyper chem After-sales service
    •Documents support: COA ,MSDS, MOA ,MS Report,HNMR Report,SDS,DMF
    • Customer Support: Shipment clearance support, quality issue support
    • Automated Customer Service: Our worldwide customers enjoy immediate 24/7 access to the HYPER CHEM support team from any location, at any time.

     

     

     

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

     

    Among them, our key client industrial sectors around the global are:

     

    Pharmaceuticals
    Nutrition Ingredients/ Dietary supplements
    Cosmetic Ingredients
    Food Ingredients
    Veterinary API
    Agriculture fertilizer
    Custom Synthesis lab supply

     

    HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

    Certificates

    Basic Info
    Product Name:

    N1-(3,5-Dimethoxyphenyl)-N2-(1-methylethyl)-N1-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-1,2-ethanediamine

    Other Name:

    1,2-Ethanediamine,N1-(3,5-dimethoxyphenyl)-N2-(1-methylethyl)-N1-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-;N1-(3,5-Dimethoxyphenyl)-N2-(1-methylethyl)-N1-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-1,2-ethanediamine;Erdafitinib;JNJ 42756493;Balversa;1620332-47-9

    CAS No.:

    1346242-81-6

    Molecular Formula:

    C25H30N6O2

    InChIKeys:

    InChIKey=OLAHOMJCDNXHFI-UHFFFAOYSA-N

    Molecular Weight:

    446.54

    Exact Mass:

    446.54

    UNII:

    890E37NHMV

    NCI Thesaurus Code:

    C103273

    ATC Code:

    L - Antineoplastic and immunomodulating agents

    Categories:

    Antineoplastic Agents

    Characteristics
    PSA:

    77.3

    XLogP3:

    3.2

    Density:

    1.2±0.1 g/cm3

    Flash Point:

    354.4±31.5 °C

    Refractive Index:

    1.618

    Water Solubility:

    <1 mg/mL

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Skin sensitization, Sub-category 1B

    Serious eye damage, Category 1

    Reproductive toxicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H302 Harmful if swallowed

    H317 May cause an allergic skin reaction

    H318 Causes serious eye damage

    H361 Suspected of damaging fertility or the unborn child

    H372 Causes damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P321 Specific treatment (see ... on this label).

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    69 Inquiries
    Country Product Purchase Quantity Date Posted
    Germany

    ERDAFITINIB

    1 KG Apr 20, 2026
    Bulgaria

    Erdafitinib

    500 MG Jun 18, 2026
    Switzerland

    1g Erdafitinib raw powder >99% purity

    1 G May 22, 2026
    Romania

    erdafitinib

    1 KG Jun 26, 2026
    Austria

    Erdafitinib

    10 G Jun 24, 2026
    United States

    Erdafitinib

    1 G Jun 20, 2026
    Czech

    Erdafitinib

    1000 MG Jun 12, 2026
    United States

    Erdafitinib

    2 G Jun 12, 2026
    United States

    erdafitinib

    1 G Jun 11, 2026
    United States

    High Quality Erdafitinib 99% powder 1346242-81-6-Shaanxi Dideu Medichem Co.Ltd

    1 G Jun 8, 2026
    United States

    Erdafitinib

    1 G Jun 5, 2026
    Italy

    erdafitinib

    1 G Jun 5, 2026
    Norway

    High-purity raw material Erdafitinib

    1 MT Jun 3, 2026
    Germany

    erdafitinib

    1 G May 28, 2026
    United States

    Erdafitinib

    3 G May 28, 2026
    Norway

    High-purity raw material Erdafitinib

    1 G May 27, 2026
    United States

    Erdafitinib-99-powder-1346242-81-6

    10 G May 27, 2026
    Germany

    Erdafitnib

    1 G May 26, 2026
    Philippines

    erdafitinib

    1 KG May 21, 2026
    United Kingdom

    Edrafitnib

    5 G May 17, 2026
    Post an enquiry for this product
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