Acridone Acetic Acid;9-Oxo-10(9H)-acridineacetic Acid
38609-97-1
99%
上海
Yuanli Tech
20kg/Drum
2026-04-27
Acridone,Acridone acetic acid,O-Carborane
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceCridanimod is a small-molecule immunomodulator and interferon inducer[1]. Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression[2].
Cridanimod is a member of acridines. It derives from an acridone.|Cridanimod is a small molecule that can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Upon intramuscular administration, cridanimod is able to induce the expression of PR in endometrial cancer. This could increase the sensitivity of endometrial cancer cells to progestin monotherapy. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone (LH) release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen release from the ovaries. This leads to an inhibition of cellular growth in estrogen-dependent tumor cells. In addition, this agent is able to increase the production and release of interferon (IFN) alpha and beta. PR is often downregulated in endometrial cancer and makes it resistant to progestin-mediated hormone therapy.Basic Info-
Product Name:
N-(Carboxymethyl)acridone
Other Name:10(9H)-Acridineacetic acid,9-oxo-;9-Oxo-10(9H)-acridineacetic acid;N-(Carboxymethyl)acridone;10-(Carboxymethyl)-9-acridinone;9-Oxo-10-acridineacetic acid;L 1;N-(Carboxymethyl)-9-acridone;Acridone-N-acetic acid;Cridanimod;10-CMA;2-(9-Oxo-9,10-dihydroacridin-10-yl)acetic acid;2-(9-Oxoacridin-10-yl)acetic acid
CAS No.:38609-97-1
Molecular Formula:C15H11NO3
InChIKeys:InChIKey=UOMKBIIXHQIERR-UHFFFAOYSA-N
Molecular Weight:253.25
Exact Mass:253.25
EC Number:1312995-182-4
UNII:X91E9EME19
DSSTox ID:DTXSID6046557
NCI Thesaurus Code:C77948
ATC Code:L - Antineoplastic and immunomodulating agents
HScode:2933990090
Categories:
Characteristics-
PSA:
57.6
XLogP3:2.7
Density:1.4±0.1 g/cm3
Melting Point:280 °C
Boiling Point:486.6°C at 760 mmHg
Flash Point:248.1±25.7 °C
Refractive Index:1.657
Water Solubility:36.8 [ug/mL]
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Acridone,Acridone acetic acid,O-Carborane
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Location:
No. 52 Huangyang Street, Zhengzhou, 450000, Henan, China.
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Total Employees:
101-200
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Year of Establishment:
2009
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Certifications:
ISO9001
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