PEG MGF CAS 108174-48-7 A popular pharmacy-grade peptide with a purity of over 99%. High quality.

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PEG-MGF (Polyethylene Glycol Modified Mechanical Growth Factor)
PEG-MGF is a synthetic peptide composed of polyethylene glycol (PEG) and mechanical growth factor (MGF). MGF is a spliced variant of insulin-like growth factor-1 (IGF-1). Its design aims to enhance the stability and half-life of the natural MGF, which is naturally produced in skeletal muscles when they are subjected to mechanical stress or injury. Core attribute
Full name: Polyethylene glycolylated mechanical growth factor
CAS number: 108174-48-7
Molecular weight: Approximately 2888.16 grams/mole (slightly varies depending on the length of the polyethylene glycol chain)
Solubility: Water-soluble
Key modification: Polyethylene glycolylation can extend its half-life to approximately 2 - 3 days, while the half-life of the unmodified MGF is only a few minutes. Mechanism of action       

Receptor binding: Binding to the insulin-like growth factor-1 receptor stimulates cell growth and tissue differentiation.
Satellite cell activation: Activating muscle satellite cells (which are crucial for muscle repair and regeneration) promotes their fusion with damaged muscle fibers.
Protein synthesis: Enhancing muscle protein synthesis and inhibiting protein breakdown to support muscle hypertrophy.
Anti-apoptotic effect: Inhibiting cell death pathways, which helps in tissue survival and repair.
Main application areas
Muscle regeneration: Accelerating the recovery from muscle damage caused by exercise and promoting muscle growth.
Wound healing: Promoting tissue repair at damaged and chronic wounds.
Osteoporosis support: Helps in the growth and remodeling of bone tissue.
Muscle atrophy: Conducting research on conditions such as muscle atrophy and cachexia associated with chronic diseases.
Safety and regulation
Limited human data: Most studies are at the preclinical stage (cell/animal experiments); no global human use approval has been obtained. Administration method: Usually through transdermal superficial administration (standard dose: 150 - 200 micrograms, 2 - 3 times per week, for 8 - 10 weeks).
Risks: Potential side effects include local transdermal superficial administration reactions, fluid retention, and unknown long-term effects. The US Food and Drug Administration (FDA) warns that due to the lack of sufficient safety data, it is not recommended to use casually.
Main differences from MGF
Natural MGF exerts a local effect in muscle tissue and has an extremely short half-life. The polyethylene glycolization technology forms a "invisible" protective layer that can reduce renal clearance rate and enzymatic degradation, achieving sustained systemic effects while still maintaining the targeted effect on muscles.
Note: PEG-MGF is commonly used in the fitness and bodybuilding fields to promote muscle growth, but its clinical application is still in the experimental stage. Consult a medical professional before use                                                                                                                                                                                                                                                                   

Company Profile    

Our company is a modern advanced enterprise specializing in production and exportation of APIs, Pharmaceutical intermediates, plant extracts etc. Our products are widely used in medicine, health care products, cosmetics, nutritional supplements and food additives areas. Our factory covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Since its establishment, the company has attached great importance to the team training and technical reform. Our modern production equipment guarantees for a fast and effective production with a superior degree of accuracy throughout the whole production line, everything is done in-house, processing, extraction, packaging and transportation of all links, ensuring maximum quality and efficiency. We are constantly research and development new ingredients and innovative new products, have earned the respect & Admiration from the worldwide customers. After years of continuous development, company has been accumulated rich experience in international trade and customer resources, established a stable customer base and perfect marketing service network. In addition, the company has established long-term technical cooperation with experts and professors from many universities and research institutes in the province.

FAQ

Q: How about the price? Can you make it cheaper?
A: We always take the customer's benefit as the top priority. Price is negotiable under different conditions, we are assuring you to get the most competitive price.

Q. What's the lead time and shipping ways?
A: We will delivery to the package by USPS, FEDEX, DHL paket and other dedicated transportation to you after receive your payment, it would take around 10-15 workdays to your address.

Q: How do i keep the peptides when i receive it ?
A: Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder store at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent                                                                                                                                                                                                                                                     

Our customers are all over the world, mainly selling in the United States, Canada, Australia, the United. Kingdom, the Ne therlands, Germany, France and other EU countries, Southeast Asia, South America, and Oceania. We also have many customers.
Our business is based on honesty and mutual trust. Sincerely look forward to establishing long-term mutually beneficial business relationships with customers around the world.