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Tesofensine 98%+

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Unit Price:

$20-23/G FOB

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CAS No.:

195875-84-4

Content:

98%

Port:

Shanghai

Packaging:

10mg/bottle 50mg/bottle

Price valid (until):

2026-05-19

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Conier Chem&Pharma Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Dicobalt Octacarbonyl,(E,E)-Farnesol,(4S,5R)-4-Methyl-5-phenyloxazolidin-2-one,Geranyl linalool

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Product Description
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Inquiry History

Description

Mol File:	195875-84-4.mol

tesofensine Chemical Properties

Boiling point	396.6±42.0 °C(Predicted)
density	1.161±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 2 mg/mL,DMSO: 1 mg/mL,Ethanol: Slightly soluble,PBS (pH 7.2): 0.14 mg/mL
form	A solid
pka	10.46±0.60(Predicted)
color	White to off-white
Stability:	Hygroscopic
InChI	InChI=1S/C17H23Cl2NO/c1-3-21-10-14-13(9-12-5-7-17(14)20(12)2)11-4-6-15(18)16(19)8-11/h4,6,8,12-14,17H,3,5,7,9-10H2,1-2H3/t12-,13+,14+,17+/m0/s1
InChIKey	VCVWXKKWDOJNIT-ZOMKSWQUSA-N
SMILES	[C@@]12([H])N(C)[C@@]([H])(CC1)C[C@H](C1=CC=C(Cl)C(Cl)=C1)[C@H]2COCC

Safety Information

MSDS Information

tesofensine Usage And Synthesis

Description	Tesofensine ((1R, 2R, 3S, 5S)-3-(3, 4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane)) is an inhibitor of neuronal reuptake of dopamine, noradrenaline, and serotonin. Tesofensine was developed for the treatment of Alzheimer's and Parkinson's disease but lacked efficacy. Meta-analysis revealed that tesofensine (0.125–1.0 mg, once daily; oral) produced dose-dependent weight loss, and 32% of obese patients had ≥ 5% weight loss following 14 wk of treatment. Weight loss was accompanied by hypophagia, suggesting an appetite suppressant action[2].
History	Tesofensine is a dopamine, serotonin, and noradrenaline (triple) reuptake inhibitor originally developed by NeuroSearch for the treatment of Alzheimer's disease and Parkinson's disease. Development of the compound for these neurological indications was unsuccessful but significant weight loss was reported during the clinical trials in Parkinson's disease. Hence, tesofensine is now being developed by NeuroSearch for the treatment of obesity and type 2 diabetes[1].
Uses	Tesofensine, is a serotonin–noradrenaline–dopamine reuptake inhibitor from the phenyltropane family of drugs, which is currently in clinical development for the treatment of obesity.

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Items	Specifications

Basic Info

Product Name:

Tesofensine

Other Name:

8-Azabicyclo[3.2.1]octane,3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-,(1R,2R,3S,5S)-;8-Azabicyclo[3.2.1]octane,3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-,[1R-(2-endo,3-exo)]-;(1R,2R,3S,5S)-3-(3,4-Dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane;Tesofensine;NS 2330

CAS No.:

195875-84-4

Molecular Formula:

C17H23Cl2NO

InChIKeys:

InChIKey=VCVWXKKWDOJNIT-ZOMKSWQUSA-N

Molecular Weight:

328.3

Exact Mass:

328.28

UNII:

BLH9UKX9V1

Categories:

Bulk Drug Intermediates

Characteristics

Seller Information

Business Type:
Trader

Main Products:
Dicobalt Octacarbonyl,(E,E)-Farnesol,(4S,5R)-4-Methyl-5-phenyloxazolidin-2-one,Geranyl linalool

Location:
11F ,#20 building, #18 Fuquan Road ,Jiangbei District, CHONGQING 400020, P.R China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
350

Total Annual Revenue:
$10 million-$25 million

Total Employees:
11-50

Year of Establishment:
2010

Inquiry History

73 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Kingdom	CAS: 195875-84-4	10 G	Oct 25, 2025
United States	tesofensine 99% Powder 195875-84-4	10 G	Jul 28, 2023
Indonesia	High quality Tesofensine 500mcg cas 195875-84-4 100pcs/bottle	4	Apr 18, 2025
United States	High Purity Tesofensine Powder 99% White Powder CAS 195875-84-4 EGC-Tesofensine Powder	1 KG	Oct 27, 2023
United States	Hot sell tesofensine Powder	1 G	Jun 22, 2023
United Kingdom	Tesofensine	1 G	May 16, 2026
United Kingdom	Tesofensine	1 G	May 10, 2026
United Kingdom	Tesofensine	10 G	Apr 20, 2026
United Kingdom	Tesofensine	100 PCS	Apr 11, 2026
United States	Tesofensine	1 KG	Mar 8, 2026
India	Tesofensine	10 MG	Feb 22, 2026
United States	Tesofensine	20 G	Feb 14, 2026
Thailand	High purity 99% Tesofensine white powder	500 MT	Dec 12, 2025
France	Tesofensine	200	Nov 1, 2025
United States	Tesofensine	5 G	Oct 8, 2025
Switzerland	tesofensine	1000 MT	Sep 4, 2025
United States	tesofensine	1 KG	Aug 4, 2025
United States	Tesofensine	10 G	Jul 5, 2025
United States	Tesofensine	1 MT	Apr 22, 2025
Germany	Tesofensine	1 KG	Apr 17, 2025

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