TB500

I. Basic Chemical Identification

• Common Names: TB500, Thymosin β4 Fragment
• Amino Acid Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln (N-terminal acetylated heptapeptide, active fragment of Thymosin β4)
• CAS Registry Number: 885340-08-9
• Molecular Weight: 889.02 Da
• Molecular Formula: C₃₈H₆₈N₁₀O₁₄

II. Key Physicochemical Properties

• Appearance: White to off-white lyophilized powder, no visible foreign matter
• Solubility: Soluble in purified water and PBS buffer, slightly soluble in organic solvents such as methanol
• Stability: Stable in a dark, sealed and dry environment; freezing at -20℃ is recommended for long-term storage

III. Synthesis & Quality Standards

Synthesis Process: Adopting standard Fmoc Solid-Phase Peptide Synthesis (SPPS) process with controllable steps, accurately achieving N-terminal acetylation modification and easy purity control.

• HPLC Purity: ≥98.0% (≥99.0% for research grade)
• Key Indicators: Qualified amino acid composition, moisture ≤8.0%, heavy metal (Pb) ≤10 ppm

IV. Storage & Transportation Requirements

• Packaging: Sealed packaging with built-in desiccant to avoid moisture absorption
• Storage: Frozen at -20℃, protected from light and moisture, avoiding high temperature and repeated freeze-thaw
• Transportation: General cargo channel, properly protected to avoid packaging damage and moisture absorption

V. Applications & Specifications

• Main Applications: Life science research; R&D of fine chemical intermediates
• Specifications: Marked "For Research/Chemical Raw Material Use Only", complying with relevant industrial standards