Over 99% concentration Retatrutide customized freeze-dried powder 5 mg, 10 mg, 20 mg Weight loss peptide

Name: Zoe
Our contact information: +852 70741845
Email: sjzes3@enshikj.com

These products are APIs (Active Pharmaceutical Ingredient) and not a finished drug.

It is intended strictly for research and laboratory use only.                                                                                                                          

Buyers are required to fully comply with all applicable laws and regulations regarding the handling and use of this material.The mechanism and molecular structure of repaglutide:
1) Tripartite action mechanism design
- GLP-1 receptor: Repaglutide can delay gastric emptying, inhibit appetite and promote insulin secretion.
- GIP receptor: Repaglutide can enhance insulin sensitivity and regulate central satiety signals.
- Glucagon receptor (GCGR): Repaglutide can activate liver energy metabolism, promote fat breakdown and glycogen breakdown, and increase basal metabolic rate.
This tripartite synergy will increase energy expenditure while reducing energy intake, significantly improving weight loss efficacy.
2) Structural optimization
- Based on the GIP structural framework, the structure was modified, and non-natural amino acids (such as introducing α-methyl leucine at position 13) were introduced to enhance receptor affinity.
- Through modification of the fatty acid side chain, the half-life was extended to 7 days, thus supporting once-weekly administration.Clinical efficacy and core data of Retatrutide:
1) Significant weight loss effect:
- During the 48-week treatment period: The average weight loss rate in the 12-mg dose group was 24.2%, significantly better than existing drugs (such as semaglutide and tesiprisine).
- Gender difference: The weight loss effect was more significant in females (28.5% compared to 21.2% in males).
- Dose-dependent: From the initial dose of 2 mg to 12 mg, the weight loss ratio increased with the increase in dose.
Comparison of weight loss effects at different doses (48-week data):
Dose: 4 mg, 8 mg, 12 mg
2) Comprehensive improvement of metabolism:
- Blood sugar control: Significantly reduces the level of glycosylated hemoglobin (HbA1c), with better results achieved when the dose is higher than 4 milligrams, and superior to dulaglutide.
- Cardiovascular metabolism: Improves triglyceride, cholesterol and blood pressure levels, potentially reducing cardiovascular risk.
- Expanded indications: Used in research for the treatment of metabolic-related diseases (such as polycystic ovary syndrome, PCOS)                                                                                                                                                             

--------- our company------

Our company is a modern advanced enterprise specializing in production and exportation of APIs, Pharmaceutical intermediates, plant extracts etc. Our products are widely used in medicine, health care products, cosmetics, nutritional supplements and food additives areas. Our factory covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Since its establishment, the company has attached great importance to the team training and technical reform. Our modern production equipment guarantees for a fast and effective production with a superior degree of accuracy throughout the whole production line, everything is done in-house, processing, extraction, packaging and transportation of all links, ensuring maximum quality and efficiency. We are constantly research and development new ingredients and innovative new products, have earned the respect & Admiration from the worldwide customers. After years of continuous development, company has been accumulated rich experience in international trade and customer resources, established a stable customer base and perfect marketing service network. In addition, the company has established long-term technical cooperation with experts and professors from many universities and research institutes in the province.                                                                                                                                                                                                                                                                                                                                                           

FAQ:

Q1. How do you ensure product quality?
A: We have a strict quality management system, all batches must be tested and meet our standards before entering the warehouse. The purity of all our products is above 99.00%, which has been verified by many American and European customers.


Q2. How to place an order with you?
A: After confirming the dosage/strength and quantity of the required product with the customer, our business personnel will make a Proforma Invoice or Sales Contract. After the customer confirms and pays for the order, we will arrange shipment for the customer as soon as possible.


Q3. What payment methods are there?
A: There are Bank Transfer, PayPal, Tether USD(USDT) and Bitcoin(BTC); we can also accept payments in CNY, for example, through Alipay or WeChat.


Q4. What shipping methods can we choose?
A: Usually express delivery is more suitable, including DHL, FedEx, UPS, etc. For Russia, we also have a dedicated express channel (double customs clearance). We will be responsible for customs clearance in the destination country, and customers are not required to cooperate with customs clearance and pay any tariffs.