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DSIP 62568-57-4 API

17 Inquiries

Unit Price: Get Latest Price
CAS No.:

62568-57-4

Grade:

Industrial Grade

Content:

99%

Port:

上海

Brand:

orient

Packaging:

1KG, 5KG, 25KG

Price valid (until):

2026-06-08

Company Type:
Trader
Location:
China
Qualification:
Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Product Name: DSIP
    Synonyms: WAGGDASGE;TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O;DELTA SLEEP-INDUCING PEPTIDE 4H2O;DSIP;DSIP 4H2O;H-TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU-OH
    CAS: 62568-57-4
    MF: C35H48N10O15
    MW: 848.82
    EINECS: 211-519-9
    Product Categories: Peptide;62568-57-4
    Mol File: 62568-57-4.mol
    Shop DSIP 62568-57-4 API-Detailed Image 1

    DSIP Chemical Properties
    Boiling point  1522.7±65.0 °C(Predicted)
    density  1.458±0.06 g/cm3(Predicted)
    storage temp.  −20°C
    pka 3.18±0.10(Predicted)
    form  Powder
    color  White to off-white
    Water Solubility  Soluble in water at 0.5mg/ml
    Sequence H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH
    InChIKey ZRZROXNBKJAOKB-GFVHOAGBSA-N

    Safety Information
    Safety Statements  22-24/25
    WGK Germany  3
    MSDS Information
    Provider Language
    SigmaAldrich English

    DSIP Usage And Synthesis
    Description Delta-sleep-inducing peptide (DSIP) is a neuropeptide with amino acid sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu and molecular mass 848.81 g/mol. DSIP occurs in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). Delta-sleep-inducing peptide is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.
    Uses Delta-sleep-inducing peptide (DSIP) was isolated, characterized, and synthesized more than 6 years ago. It can help relieve stress and aches that keep you from restful sleep. It was first proposed as a sleep-peptide and this remains the prevalent impression of its function. DSIP is a natural sleep-promoting nonapeptide with a few beneficial functions. The peptide has been used to treat poor sleep, pain conditions, stress-related symptoms, and more. Delta-Sleep Inducing Peptide trifluoroacetate salt H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH trifluoroacetate salt is a useful research chemical compound.
    Uses DSIP is thought to increase sleep regulation, reduce motor activity to improve deep sleep, stimulate ACTH and LH levels, and reportedly normalize blood pressure. DSIP can change the serum level of some hormones, such as adrenocorticotropic hormone, somatostatin, serotonin, etc.
    Definition Emideltide or DSIP is a nonapeptide that is found in neurons, peripheral organs, and plasma. This neuropeptide induces mainly delta sleep in mammals. In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal.
    benefits Can restore disturbed sleep patterns;Can promote LH and GH release;Can reduce persistent/chronic pain;Can modulate cortisol production.
    benefits Delta sleep-inducing peptide (DSIP), which suppresses excess production of free radicals in the CNS and prevents neuron death during the body’s response to stress. DSIP activates oxidative phosphorylation and increases the resistance of brain neurons to hypoxia in vitro. It decreases the sensitivity of neuron receptors to the excitatory actions of glutamate. Thus, DSIP helps to prevent excitotoxicity, which may underlie its neuroprotective action in cerebral ischemia[1].
    References [1] E. Koplik. “Delta sleep-inducing peptide and Deltaran: Potential approaches to antistress protection.” Neuroscience and Behavioral Physiology 38 1 (2008): 953–957.
    Physiological effects Delta sleep-inducing peptide (DSIP) has several physiological effects in addition to its ability to promote sleep in animals. It is also involved in neuroendocrine regulation and release of anterior pituitary hormones. In rodents and humans, Delta sleep-inducing peptide (DSIP) influence in the secretion of adrenocorticotropic hormone (ACTH), luteinizing hormone (LH) and growth hormone (GH). It also plays a role in the regulation of the circadian rhythms and and can help restore disturbed patterns of sleep.
    Description DSIP Synthetic is a single, non-glycosylated polypeptide chain containing 15 amino acids, having a molecular mass of 1419.55  Dalton and a Molecular formula of C62H98N16O22.  
    Background Delta Sleep-Inducing Peptide (DSIP), also known as Sleep-Promoting Peptide, is a neuropeptide that has been the subject of extensive research due to its potential role in sleep regulation, stress response, and neuroprotection. This nonapeptide, first isolated from the cerebral venous blood of rabbits during sleep, has been shown to induce slow-wave sleep, modulate pain perception, and exhibit potential antioxidant and immunomodulatory properties.


    DSIP's primary function is its interaction with the sleep regulatory system. By modulating the release of certain neurotransmitters, DSIP can influence sleep patterns, particularly promoting slow-wave sleep, the most restorative stage of sleep. Studies by Kovalzon et al. (2011) have demonstrated that DSIP can enhance sleep quality in rats, suggesting potential applications in sleep disorders and the promotion of healthy sleep patterns.


    In addition to its sleep-inducing effects, DSIP has been shown to possess neuroprotective properties. Research by Zolotarev et al. (2014) found that DSIP could protect neurons from oxidative stress, suggesting potential applications in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.


    Given its sleep-inducing and neuroprotective effects, DSIP has been proposed as a potential therapeutic agent for a variety of conditions, including sleep disorders, chronic pain, and neurodegenerative diseases. For instance, a study by Spong et al. (2016) found that DSIP could improve sleep quality in patients with chronic insomnia, indicating its potential as a therapeutic agent in the treatment of sleep disorders.


    While research on DSIP is promising, it is important to note that most studies have been conducted in animals or in vitro. More research is needed to fully understand the potential effects and applications of DSIP in humans. However, the existing body of research suggests that DSIP could be a promising tool in the treatment of sleep disorders, chronic pain, and neurodegenerative diseases.


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    Q1:Do you provide sample?

    A: Yes, we can provide free sample, you only need pay the shipping cost.

    Q2: What is the lead time?

    A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

    Q3: How can I buy? What is the payment method?

    A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer, 

    Q4:What if there are quality issues?

    A:We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

    Basic Info
    Product Name:

    Dsip

    CAS No.:

    62568-57-4

    Molecular Formula:

    C35H48N10O15

    InChIKeys:

    ZRZROXNBKJAOKB-GFVHOAGBSA-N

    Molecular Weight:

    848.8

    Exact Mass:

    848.33006086

    UNII:

    YN28Z5YZ73

    Categories:

    Inhibitor Drugs

    Characteristics

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutical intermediates,peptides,electronic chemicals

    Location:

    Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

    Payment Terms:

    100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    51-100

    Year of Establishment:

    2024

    A reliable supplier is like insurance.

    We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals,food additives, and other fine chemical products.
    Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

    Website: orientchem.cc
    Email: scarlett@orientchem.cc
    WhatsApp: +86 17753254221

  • Inquiry History
    17 Inquiries
    Country Product Purchase Quantity Date Posted
    Germany

    Dsip

    1 MT Apr 26, 2026
    United States

    DSIP

    10 MT Mar 12, 2026
    United States

    DSIP

    10 MG Jan 12, 2026
    United States

    DSIP

    1 G Nov 10, 2025
    United States

    dsip

    Oct 20, 2025
    United States

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    100 MG Jun 24, 2025
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    Adipotide 5mg 10vial kit

    1 MT Feb 25, 2024
    United States

    Dsip

    10 G Jan 12, 2026
    United States

    dsip

    100 G May 17, 2026
    United States

    DSIP

    10 MT Apr 27, 2026
    United States

    DSIP

    10  Apr 13, 2026
    United States

    DSIP

    1 MT Apr 10, 2026
    United States

    Dsip

    100 MT Feb 3, 2026
    United States

    Dsip

    1 MT Dec 17, 2025
    Italy

    Adipotide

    100 MG Jun 2, 2024
    United States

    DSIP

    100 MG Nov 28, 2025
    United States

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