5-amino fat-burning weight loss product. Peptide powder for freezing is produced in China.

5-Aminosalicylic acid

Benzoic acid,5-amino-2-hydroxy-;Salicylic acid,5-amino-;5-Amino-2-hydroxybenzoic acid;2-Hydroxy-5-aminobenzoic acid;3-Carboxy-4-hydroxyaniline;Pentasa;Mesalamine;5-Aminosalicylic acid;Mesalazine;Asacol;5-ASA;Salofalk;Claversal;Asacolitin;Salozinal;Mesacol;Asacolon;Fisalamine;Lixacol;Mesasal;m-Aminosalicylic acid;Rowasa;NSC 38877;Canasa;Ipocol;Asalit;Lialda;Mesalsal;Novo-5 ASA;Colasa;Apriso;Mezavant;Rovasa;Fivasa;Delzicol;61513-32-4

89-57-6

C7H7NO3

InChIKey=KBOPZPXVLCULAV-UHFFFAOYSA-N

153.14

153.14

2090421

201-919-1

4Q81I59GXC

759301|38877

DTXSID5024506

C29249

White to pinkish crystals

A07EC02|A - Alimentary tract and metabolism

2922509090

Emollient

83.6

1.3

off-white to gray tablets

1.5±0.1 g/cm3

283 °C

403.9ºC at 760 mmHg

279-281°C

1.691

H2O: <0.1 g/100 mL at 21 ºC;soluble in dimethyl sulfoxide.

2-8°C

6.10X10-8 mm Hg at 25 deg C (est)

Peritoneal-mouse LD50: 5000 mg/kg; oral-mouse LDL0: 313 mg/kg

Flammable; burning produces toxic nitrogen oxide fumes

Henry's Law constant = 5.02X10-12 atm-cu m/mol at 25 °C (est)

Mesalamine's production and use in the manufacture of light-sensitive paper, azo and sulfur dyes and as a gastrointestinal medication may result in its release to the environment through various waste streams. If released to air, an estimated vapor pressure of 6.1X10-8 mm Hg at 25 °C indicates mesalamine will exist in both the vapor and particulate phases in the atmosphere. Vapor-phase mesalamine will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 18 hrs. Particulate-phase mesalamine will be removed from the atmosphere by wet or dry deposition. Mesalamine does contain chromophores that absorb at wavelengths >290 nm and therefore may be expected to be susceptible to direct photolysis by sunlight. If released to soil, mesalamine is expected to have very high mobility based upon an estimated Koc of 10. Estimated pKa values of 2.09, 5.26 and 13.64 indicate that this compound will dissociate to the zwitterion form in the environment. Volatilization from moist soil surfaces is not expected to be an important fate process based upon an estimated Henry's Law constant of 5.0X10-12 atm-cu m/mole. Mesalamine is considered completely biodegradable under anaerobic conditions as was indicated by 95.6% methane production following acclimation. If released into water, mesalamine is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is not expected to be an important fate process based upon this compound's estimated Henry's Law constant. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. Occupational exposure to mesalamine may occur through inhalation and dermal contact with this compound at workplaces where mesalamine is produced or used. Use data indicate that the general population may be exposed to mesalamine via dermal contact with products containing this compound as well as via ingestion following administration of drugs containing mesalamine, a gastrointestinal anti-inflammatory. (SRC)

134.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Decomposes at approx 280 °C|Hydroxyl radical reaction rate constant = 2.09X10-11 cu cm/molec-sec at 25 °C (est)

Sensitive to moisture. Water insoluble.

Acids, Carboxylic

5-AMINOSALICYLIC ACID is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizers. (NTP, 1992)