GHK-Cu (Copper Tripeptide-1 / Glycyl-Histidyl-Lysine Copper Complex)
Basic Chemical Specifications
- CAS No.: 49557-75-7
- Amino Acid Sequence: Gly-His-Lys (GHK) chelated with Cu²⁺
- Molecular Formula: C₁₄H₂₄CuN₆O₄
- Molecular Weight: 403.93 Da
- Appearance: Fine deep blue lyophilized crystalline powder
- Standard Packing: 10mg / 30mg / 50mg / 100mg per sterile glass vial
Product Introduction & Core Mechanism
GHK-Cu, also known as Copper Tripeptide-1, is a naturally occurring copper-binding tripeptide first isolated from human plasma. The GHK tripeptide tightly chelates bioavailable copper ions to form a stable complex, safely transporting Cu²⁺ into cells without the side effects of free copper salts. It regulates over 4,000 human genes and serves as a core research compound for dermatology, tissue repair, anti-aging and muscle regeneration studies.
Core research functions:
- Boost collagen & elastin synthesis for tissue remodeling
Activates fibroblast proliferation and TGF-β signaling to upregulate Type I/III collagen, elastin and glycosaminoglycan production; meanwhile inhibits matrix metalloproteinases (MMPs) that break down skin and connective tissue, improving skin firmness, smoothing fine lines and accelerating wound closure. - Powerful antioxidant & anti-inflammatory protection
Delivers copper cofactor to activate SOD antioxidant enzymes, neutralizes ROS free radicals; suppresses NF-κB, TNF-α and IL-6 pro-inflammatory cytokines to relieve chronic oxidative tissue damage and post-injury swelling. - Promote angiogenesis & hair follicle vitality
Upregulates VEGF expression to support microvascular blood circulation; widely used in hair regeneration lab models to strengthen follicle structure and extend growth phase. - Muscle repair & anti-senescence support
Enhances connective tissue recovery after exercise-induced micro-tears, reduces cellular senescence markers and balances extracellular matrix metabolism in muscle and organ tissue. - Gentle cell penetration & low cytotoxicity
Small molecular tripeptide easily crosses cell membranes; the chelated copper structure avoids metal ion oxidation and cell toxicity, offering superior biocompatibility compared to inorganic copper raw materials.
Our GHK-Cu Product Competitive Advantages
- Ultra-high purity ≥99%
Every batch passes HPLC and LC-MS mass spectrum identification. Complete COA, HPLC chromatogram, heavy metal and low-endotoxin test reports are provided for all bulk orders; no unchelated free copper or peptide degradation impurities. - Vacuum freeze-drying craft
Full moisture removed without preservatives, fully locks complete biological activity. The lyophilized blue powder resists moisture absorption and oxidation during long-distance air & sea cross-border shipping, with a 24-month stable shelf life. - GMP clean-room sterile production
Independent single sealed vial packaging to avoid cross-contamination. Custom private labels, bottle sizes and bulk packing service available for cosmetic raw material suppliers and global lab resellers. - Excellent water solubility
Rapidly dissolves in bacteriostatic water or cosmetic aqueous base to form uniform clear blue solution without sediment, convenient for serum - Complete professional technical support
We supply detailed reconstitution guide, storage specification, laboratory dosage reference and full batch traceability documents for distributors.
Storage & Reconstitution Instructions
- Unopened lyophilized powder: Long-term storage at -20°C away from light and humidity, shelf life up to 24 months; short transit storage at 2–8°C is acceptable.
- Reconstitution solvent: Sterile bacteriostatic water or purified cosmetic water
- Operation tip: Slowly inject solvent along the inner vial wall, swirl gently instead of violent shaking to prevent peptide complex dissociation.
- Reconstituted blue solution: Seal tightly and refrigerate at 2–8°C, finish use within 14 days; avoid repeated freeze-thaw cycles.
Global Wholesale Cooperation Support
- Flexible MOQ & tiered large-volume discount for stable VIP long-term partners
- Low-risk dedicated shipping channels for USA, EU, Brazil, Australia with lower customs detention probability
- Exclusive one-on-one VIP account manager, fast response and professional reshipping solution for logistics issues
GHK-Cu Copper Tripeptide Lyophilized Powder | 99% High Purity Research Peptide
Famous blue copper chelated tripeptide for dermatology and tissue regeneration research.
Core research directions: stimulate collagen & elastin production, anti-wrinkle & skin repair, strong antioxidant anti-inflammation, hair follicle revitalization and muscle recovery study. Safe chelated copper complex without free metal toxicity.
✅ Purity ≥99% verified by HPLC & mass spectrum
✅ Specifications: 10mg / 30mg / 50mg / 100mg per sterile vial
✅ Full set of official COA testing documents attached
✅ Freeze-dried stable blue powder suitable for worldwide delivery
✅ Clear blue solution after reconstitution, easy cosmetic & lab formulation
✅ Custom packaging & favorable bulk wholesale price
| Items | Specifications |
| Purity | ≥99% verified by HPLC & mass spectrum
|
| Specifications | 10mg / 30mg / 50mg / 100mg per sterile vial
|
| storage | at -20°C away from light and humidity, shelf life up to 24 months; |
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We have been deeply engaged in the peptide industry for many years, serving as a source biotechnology factory integrating R&D, synthesis, production and sales.
We strictly follow production and quality control standards, with the whole process adopting aseptic production and independent lyophilization and packaging. Our products feature stable appearance, good solubility and high activity retention.
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