High Purity 2B4C CAS 877-37-2 Organic Chemical Intermediate

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CAS No. 877-37-2, is an important organic synthesis intermediate. The compound has the molecular formula C₉H₈BrClO and a molecular weight of 247.52. It appears as a white to off-white crystalline powder or solid. The purity specification is typically 98%–99%.

Physical and Chemical Properties:

This product has a boiling point of 296.7°C (760 mmHg), a density of approximately 1.518 g/cm³, and a flash point of 133.2°C. Its melting point is 77–79°C. It is highly soluble in organic solvents and slightly soluble in water. It is recommended to store the product in a sealed container protected from light at 4°C to ensure stability.

Core Application Areas:

Pharmaceutical Impurity Reference Standards: A key impurity standard for (Bupropion), used to streamline analytical method development, method validation, and quality control in Abbreviated New Drug Applications (ANDAs). As a reference standard, its characterization data complies with regulatory guidelines.

Organic Synthesis Intermediates: The molecule contains both bromine and chlorine halogen substituents, as well as a ketone carbonyl functional group, conferring reactivity as an electrophilic alkylating agent. It can be used to prepare phenethylamine derivatives and other bioactive molecules.

Pharmaceutical and Pesticide R&D: As an α-halo ketone, it has application value in the synthetic processes of antidepressants, antipsychotics, and pesticides.

Safety and Storage Information:

This product is for research use only and must not be used on humans. Laboratory safety protocols must be followed during handling; it is recommended to work in a fume hood and wear appropriate personal protective equipment. Due to the presence of bromine and chlorine, it may present certain irritants and health risks; avoid inhaling dust or skin contact. Store in a cool, dry place away from light.

The standard packaging size for this product is 25 kg per drum, and custom packaging is available. For shipping, bulk orders can be shipped via sea or air freight; samples and small-volume orders can be shipped via international couriers such as DHL, FedEx, EMS, and TNT.

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