Semaglutide 10mg Lyophilized Powder | SM10 | CAS 910463-68-2 | GLP-1 Peptide

Guangzhou Boyuan Outdoor Products Co., Ltd. is a modern enterprise located in Guangzhou, China, specializing in the research, development, and supply of high-purity peptide raw materials. Although the company name includes "Outdoor Products," Boyuan's core business is deeply rooted in the fields of biochemistry and laboratory research. The company is dedicated to providing high-quality peptide products to research institutions, laboratories, and professional buyers worldwide. With years of industry experience, a strict quality control system, and an efficient global logistics network, Boyuan has rapidly developed into a trusted partner in the peptide raw material supply chain. The company's main products cover dozens of popular research peptides, including Semaglutide, Tirzepatide, Retatrutide, HCG, TB-500, GHK-CU, and many others, with specifications ranging from milligram to gram levels to meet the procurement needs of different scales. Boyuan always adheres to the business philosophy of "Quality First, Customer Supreme." Each batch of products is tested by High-Performance Liquid Chromatography (HPLC) to ensure purity of over 99%, and third-party test reports can be provided upon customer request. In terms of warehousing and logistics, Boyuan has multiple warehouses within China and overseas, enabling rapid sorting and global shipping, supporting cold chain transport to ensure the stability of peptide products during transit. Whether for small batch purchases or bulk orders, Boyuan offers flexible and efficient solutions. Furthermore, Boyuan has a professional technical support and customer service team, providing product consultation, usage guidance, and after-sales follow-up, truly delivering a worry-free experience from order placement to receipt.

Semaglutide 10mg (Catalog No. SM10), as one of Boyuan's star products, appears as a white, loose lyophilized powder. The freeze-drying process maximizes the preservation of the peptide's biological activity and chemical stability. Each vial is precisely filled with 10mg, with 10 vials per box, suitable for medium- to long-term research use. The product requires reconstitution before use. Recommended reconstitution solvents include sterile water for research use or 0.9% saline. The specific operation steps are as follows: first, briefly centrifuge the vial to collect the lyophilized powder at the bottom; then add an appropriate volume of solvent according to the desired final concentration. For example, adding 1 mL of solvent yields a concentration of 10 mg/mL, while adding 2 mL yields 5 mg/mL. After adding the solvent, gently swirl the vial until the powder is completely dissolved. Avoid shaking to prevent peptide aggregation or degradation. The reconstituted solution should be clear and transparent without visible particles. To maintain product stability, it is recommended to aliquot the reconstituted solution into multiple small tubes to avoid repeated freeze-thaw cycles. Under refrigeration at 4°C, the reconstituted Semaglutide remains stable for 24 to 48 hours. If aliquoted and frozen at -20°C, it can be stored for about one month. Unopened lyophilized powder should be stored at -20°C in a dry, light-protected environment, with a shelf life of 24 months.

From a mechanism of action perspective, Semaglutide is a highly selective GLP-1 receptor agonist. When it binds to GLP-1 receptors on the surface of pancreatic beta cells, it activates the intracellular cyclic adenosine monophosphate (cAMP) signaling pathway, thereby promoting glucose-dependent insulin secretion. The term "glucose-dependent" means that Semaglutide strongly stimulates insulin release only when blood glucose levels are elevated, and its effect is significantly reduced when blood glucose is normal, a characteristic that greatly lowers the risk of hypoglycemia. At the same time, Semaglutide inhibits the secretion of glucagon from pancreatic alpha cells, reducing hepatic glucose output. At the gastrointestinal level, Semaglutide delays gastric emptying, prolonging the time food remains in the stomach and thus slowing glucose absorption. At the central nervous system level, Semaglutide can cross the blood-brain barrier and act on GLP-1 receptors in the hypothalamic arcuate nucleus, enhancing satiety signals and suppressing appetite. These combined effects make Semaglutide effective in both blood glucose regulation and body weight control. In preclinical research, Semaglutide is widely used to explore mechanisms in areas such as type 2 diabetes, obesity, non-alcoholic fatty liver disease, and cardiovascular protection. Its long-acting properties make it particularly suitable for experimental models requiring long-term intervention, such as high-fat diet-induced obese mouse models or streptozotocin-induced diabetic rat models.

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