99% Purity Survodutide CAS 2805997-46-8 GLP-1 and Glucagon Receptor Dual Agonist Peptide for Research Use

99% Purity Survodutide CAS 2805997-46-8 GLP-1 and Glucagon Receptor Dual Agonist Peptide for Research Use

Survodutide (also known as BI 456906) is a long-acting synthetic peptide analog that functions as a dual agonist for both the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCGR). This product is supplied as a lyophilized powder with ≥99% purity (tested by HPLC).

For laboratory research purposes only. Not for human or veterinary use. Not for diagnostic or therapeutic applications.

Survodutide comprises a 29 amino acid linear synthetic peptide with a C18 fatty diacid moiety that prolongs its half-life through albumin binding. It contains a non-coded amino acid residue (1-aminocyclobutane-1-carboxylic acid, Ac4c) at position 2 for enhanced proteolytic stability, protecting against dipeptidyl peptidase-4 degradation. The peptide is C-terminally amidated for additional stability.

In vitro studies demonstrate that Survodutide exhibits potent agonist activity at both receptors, with EC50 values of 0.33 nM for GLP-1R and 0.52 nM for GCGR in CHO-K1 cells. The dual agonism mechanism allows researchers to investigate both GLP-1R-mediated insulin sensitization pathways and GCGR-driven energy metabolism pathways.

Key Research Applications: GLP-1 receptor signaling studies, GCGR pathway research, dual receptor mechanism investigations, metabolic pathway research, cellular energy metabolism studies, liver metabolism research.

Research Applications (for laboratory use only)

• Dual receptor signaling studies (GLP-1R and GCGR pathways)

• Metabolic pathway and energy expenditure research

• Liver metabolism and hepatic function studies

• Cellular energy metabolism research

• Receptor binding and activation assays

• Peptide-based research compound development

Packaging Structure (From Outer to Inner)

Level Description

Outer Packaging Standard cardboard box

Middle Packaging Product box (branded/plain) containing a plastic box inside

Inner Packaging Plastic box holding 10 glass vials with foam or partition protection

Vial Clear glass vial, aluminum-plastic flip-off seal, labeled with product name, dosage, and batch number

Each Plastic Box Contains:
10 vials of Survodutide (10mg per vial).

The vial is individually sealed with label.

Foam or plastic partition to prevent vials from bumping into each other

Shipping Methods & Delivery Time
Shipping Method Cost Delivery TimeSpecial Line/ Express $40 (under 5kg) ~14 days
UK Special Line Same as above ~25 days (slightly delayed)
UPS / FedEx $70 7-10 daysShipping Policies

Policy Details
Free Shipping On orders over $1000
Remote Area Fee Some remote areas may incur an extra $35 (as determined by FedEx/UPS)
Lead Time 3-5 business days after payment confirmation

Frequently Asked Questions (FAQ)
Q1: Can I get a sample before placing an order?

Yes, samples are available upon request. Samples are not provided for free. You will need to pay for both the sample cost and the shipping fee. The sample fee will be deducted from your bulk order payment once you proceed with a formal order.

Q2: What payment methods do you accept?

We accept wire transfer (T/T), PayPal, and bank transfer. You may choose the most convenient method for you.

Q3: How and when can I receive my order after payment?

Small quantity orders: Shipped via international express (DHL, FedEx, UPS, etc.). Delivery time: 7-10 days after shipment.

Large quantity orders: Shipped by sea. Delivery time: 15-30 days depending on the destination port.

Special line: ~14 days delivery time (under 5kg, $40).

Q4: Can I use my own label or packaging?

Yes, OEM service is available for bulk orders. We can customize labels, vial dosage, vial cap color, and packaging according to your requirements. Please contact us for details.

Q5: What is your MOQ (Minimum Order Quantity)?

Retail MOQ: 1 kit/dosage/item

Customized packaging (e.g., custom vial size, cap color): 20-50 kits/dosage/item

Q6: Do you provide a Certificate of Analysis (COA) with each order?

Yes, each batch comes with a COA (HPLC purity test report). Third-party testing is also available upon request.

Q7: How should I store the peptide?

Store at -20°C, protected from light, and keep sealed. Once reconstituted, refrigerate at 2-8°C and use within the recommended timeframe.

Q8: What documents will be included with my shipment?

Commercial invoice, packing list, COA, and MSDS will be included with each shipment.