Cafestol
469-83-0
Pharmaceutical grade
99%
PNQ
bag
2028-05-22
Apigenin,PQQ,NMNH
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceCafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway. Cafestol contributes to its beneficial effects through various biological activities such as chemopreventive, antitumorigenic, hepatoprotect
Cafestol is an organic heteropentacyclic compound and furan diterpenoid with formula C20H28O3 obtained from the unsaponifiable fraction of coffee oil (a lipid fraction obtained from coffee beans by organic solvent extraction). It has a role as a plant metabolite, an apoptosis inducer, a hypoglycemic agent, an angiogenesis inhibitor, an antineoplastic agent, an antioxidant and an anti-inflammatory agent. It is an organic heteropentacyclic compound, a tertiary alcohol, a diterpenoid, a member of furans and a primary alcohol.CertificatesBasic Info-
Product Name:
Cafestol
Other Name:5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b,11,12-dodecahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)-;Cafestol;5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b,11,12-dodecahydro-7-hydroxy-10b-methyl-,[3bS-(3bα,5aβ,7β,8β,10aα,10bβ)]-;(3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol;Cafesterol
CAS No.:469-83-0
Molecular Formula:C20H28O3
InChIKeys:InChIKey=DNJVYWXIDISQRD-HWUKTEKMSA-N
Molecular Weight:316.441
Exact Mass:316.43
UNII:AC465T6Q6W
DSSTox ID:DTXSID3040986
Categories:
Characteristics-
PSA:
53.6
XLogP3:4.03
Density:1.2±0.1 g/cm3
Melting Point:153-155 °C @ Solvent: Benzene, Ligroine
Boiling Point:468.6±45.0 °C at 760 mmHg
Flash Point:237.2±28.7 °C
Refractive Index:1.604
Vapor Pressure:0mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Apigenin,PQQ,NMNH
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Location:
Room 1006, Building C6, Economic Development Wanda, Caidian District, Wuhan City, Hubei Province
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Payment Terms:
100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
Less than $1 million
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Total Employees:
5-10
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Year of Establishment:
2021
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