Top quality Black Pepper extract bulk powder Piperine

Piperine is an active alkaloid found in black pepper, a lipophilic small-molecule substance that inhibits drug-metabolizing enzymes and P-glycoprotein in the liver and intestines, promoting the absorption of various nutrients. It is commonly used as a "bio-enhancer" with mild anti-inflammatory, antioxidant, metabolic-boosting, and digestive effects. It significantly enhances the bioavailability of ingredients such as curcumin and berberine. Currently, it is widely utilized in dietary supplements, functional foods, and certain pharmaceutical formulations to improve the absorption of other components.

Product name:Black Pepper extract  (Piperine)

Appearance: light Slightly yellow powder

MF： C17H19NO3

MW： 285.34

CAS： 94-62-2

Purity:>95%

Packaging: 25KG/drum

Black Pepper is the semi ripe and fresh red fruit of Piper nigrum, a pepper plant in the family Piperaceae. After harvesting, it is directly dried, causing the skin to shrink and oxidize to turn black. It is the most fragrant and flavorful pepper.

White pepper is a ripe fruit that is harvested, peeled off, sun dried, and turns white.Black pepper, white pepper, green pepper, and red pepper all come from the same plant, and different types of pepper are obtained by different harvesting maturity and processing methods.

Piperine is the main active alkaloid of pepper, and its core mechanism is to inhibit intestinal/hepatic CYP3A4 metabolic enzymes and P-glycoprotein efflux pumps, reversibly increase intestinal membrane permeability, promote gastrointestinal blood flow, and significantly enhance the bioavailability of drugs and nutrients; Simultaneously activating TRPV1 receptors to generate warmth sensation, dilate blood vessels, and promote digestion and metabolism; And by inhibiting NF κ B, COX-2, iNOS and activating the Nrf2 antioxidant pathway, it exerts multiple activities such as anti-inflammatory, antioxidant, regulating glucose and lipid metabolism, and neuroprotection.

The potential benefits of piperine include:

1) Enhancing bioavailability: Inhibiting metabolic enzymes and efflux transporters to improve nutrient absorption and utilization.

2) Promote digestion and improve gastrointestinal health: stimulate gastrointestinal secretion, enhance gastrointestinal peristalsis, relieve bloating and indigestion.

3) Anti inflammatory and analgesic: Inhibit inflammatory factors and pro-inflammatory enzymes to alleviate chronic inflammation.

4) Regulating metabolism: assisting in regulating blood sugar and blood lipids, inhibiting fat accumulation, and aiding in weight management.

5) Antibacterial: It has a certain inhibitory effect on some harmful microorganisms.

Dietaray supplement 

Pet health products

Food and Soup

Low MOQ

Support customized packaging

Support free samples

Support third-party testing

Low intake of piperine is safe, but excessive intake can cause gastrointestinal discomfort such as burning, nausea, and diarrhea in the stomach.

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