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Baicalein

Unit Price: Get Latest Price
CAS No.:

491-67-8

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

g/kg

Price valid (until):

2026-07-03

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

  • Product Description

  • Seller Information

  • Description
    Baicalein is a highly bioactive plant-derived flavone that functions as a potent anti-inflammatory, neuroprotective, and antioxidant compound. Extracted from the roots of Scutellaria baicalensis (Chinese Skullcap), its primary mechanism of action centers on the potent, selective inhibition of 12/15-lipoxygenase (12/15-LOX) and the suppression of systemic inflammatory cascades. [1, 2, 3, 4, 5]
    Unlike many other flavonoids, baicalein is exceptionally fast-acting because it readily crosses the blood-brain barrier to protect central nervous tissues from acute and chronic injury. [1, 2]
    Core Health Functions
    • Suppresses Severe Inflammation: It directly inhibits the 12/15-lipoxygenase (LOX) pathways and blocks the NF-κB signaling cascade. This sharply reduces the production of leukotrienes and pro-inflammatory cytokines, protecting organs from inflammatory tissue damage. [1, 2, 3, 4, 5]
    • Protects and Repairs Brain Cells: It exerts profound neuroprotective effects by reducing neuroinflammation, preventing the aggregation of alpha-synuclein and amyloid-beta proteins (key markers in Parkinson's and Alzheimer's diseases), and promoting cognitive recovery after brain injuries. [1, 2, 3, 4, 5]
    • Mitigates Liver Damage: It acts as a powerful anti-fibrotic agent in the liver. It triggers apoptosis (programmed cell death) in activated hepatic stellate cells, which helps slow down or prevent the progression of liver fibrosis and cirrhosis. [1, 2, 3, 4]
      • Combats Cellular Oxidative Stress: It serves as a direct free radical scavenger and upregulates the body's natural internal antioxidant enzymes. It prevents lipid peroxidation in cell membranes, preserving structural cellular integrity. [1, 2, 3, 4, 5]
      • Exhibits Anti-Tumor Activity: In oncological research, baicalein stops the proliferation of multiple cancer lines (including breast, liver, and colon cancers). It achieves this by inducing cell cycle arrest, triggering apoptosis, and blocking tumor angiogenesis (blood vessel growth). [1, 2, 3, 4, 5]
      • Supports Cardiovascular Health: It promotes vasorelaxation (widening of blood vessels) by stimulating nitric oxide production and modulating calcium channels, which naturally helps lower elevated blood pressure. [1, 2, 3, 4, 5]

    Basic Info
    Product Name:

    Baicalein

    Other Name:

    4H-1-Benzopyran-4-one,5,6,7-trihydroxy-2-phenyl-;Flavone,5,6,7-trihydroxy-;Baicalein;5,6,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one;5,6,7-Trihydroxyflavone;Noroxylin;NSC 661431;Baikalein

    CAS No.:

    491-67-8

    UN No.:

    491-67-8

    Molecular Formula:

    C15H10O5

    InChIKeys:

    FXNFHKRTJBSTCS-UHFFFAOYSA-N

    Molecular Weight:

    270.24

    Exact Mass:

    270.05282342

    UNII:

    49QAH60606

    NSC Number:

    729192|661431

    DSSTox ID:

    DTXSID2022389

    HScode:

    2932999099

    Categories:

    Chinese Herbs

    Characteristics
    Collision Cross Section:

    153.8 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

    Location:

    Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    51-100

    Year of Establishment:

    2019

  • Country Product Purchase Quantity Date Posted
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