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Magnolol

Name: Magnolol
Brand: Cuicheng Bio
SKU: pr2606011580
Price: 100 USD
Availability: InStock

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Unit Price:

$100-120/G FOB

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CAS No.:

528-43-8

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

g/kg

Price valid (until):

2026-07-03

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
Seller Information
Inquiry History

Description

Magnolol is a highly versatile, bioactive polyphenolic lignan extracted primarily from the bark of the Magnolia officinalis tree. Its standout biological functions are focused on neurological relaxation, stress relief, and systemic inflammation reduction by modulating critical pathways like GABA_A and PPARγ receptors. [1, 2, 3, 5]

Unlike quercetin and fisetin, which function heavily as general free radical scavengers or targeted senolytics, magnolol is highly celebrated for its direct muscle-relaxant, sedative, and anti-anxiety activities. [1, 2, 3, 4, 5]

Core Health Functions

Reduces Anxiety and Promotes Sleep: It serves as a potent positive allosteric modulator of GABA_A receptors. This action enhances the body's calming neurotransmitters, effectively mimicking anti-anxiety and sedative behaviors without standard pharmaceutical side effects. [1, 2, 3, 4, 5]
Alleviates Inflammatory Pain: It inhibits nociception (pain signaling) by interacting with NMDA and mGluR5 glutamate receptors, safely dampening internal and localized pain responses. [1]
- Combats Cellular Inflammation: It aggressively blocks pro-inflammatory signaling cascades, such as the NF-κB pathway, and suppresses inflammatory enzymes like COX-2 and iNOS. [1]
- Protects and Promotes Brain Health: It easily manages neurodegenerative pathways by shielding neurons from toxicity, diminishing lipid peroxidation in the striatum, and encouraging healthy neurite growth. [1]
- Supports Metabolic Balance: It acts as an agonist for PPARγ (peroxisome proliferator-activated receptor gamma). This function aids in decreasing fat accumulation, increasing fat oxidation, and improving insulin sensitivity. [1, 2]
- Restrains Tumors in Preclinical Models: In multi-target testing against stomach, colon, and lung cancers, it triggers cell cycle arrest and apoptosis (programmed cell death) while blocking the growth of tumor blood vessels. [1, 2]
Structural & Extraction Background
- Natural Source: It is natively gathered from Magnolia officinalis (Magnolia bark), a staple element in Eastern medical practices.
- The Honokiol Connection: In nature, magnolol is almost always harvested alongside its structural optical isomer, honokiol. Together, they exert a highly synergistic effect on mental relaxation and cell defense

Basic Info

Product Name:

Magnolol

Other Name:

[1,1′-Biphenyl]-2,2′-diol,5,5′-di-2-propen-1-yl-;2,2′-Bichavicol;2,2′-Biphenyldiol,5,5′-diallyl-;[1,1′-Biphenyl]-2,2′-diol,5,5′-di-2-propenyl-;5,5′-Di-2-propen-1-yl[1,1′-biphenyl]-2,2′-diol;Magnolol;5,5′-Diallyl-2,2′-biphenyldiol;NSC 293099;2-(2-Hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphenol

CAS No.:

528-43-8

Molecular Formula:

C18H18O2

InChIKeys:

InChIKey=VVOAZFWZEDHOOU-UHFFFAOYSA-N

Molecular Weight:

266.34

Exact Mass:

266.33

UNII:

001E35HGVF

NSC Number:

293099

DSSTox ID:

DTXSID0044076

HScode:

2907299090

Categories:

Bleaching Agent

Characteristics

PSA:

40.5

XLogP3:

Appearance:

White powder; Bitter aroma

Density:

1.1±0.1 g/cm3

Melting Point:

103 °C

Boiling Point:

178-180 °C @ Press: 1 Torr

Flash Point:

184.5±21.9 °C

Refractive Index:

1.602

Water Solubility:

In water, 1.24 mg/L at 25 deg C (est)

Storage Conditions:

2-8°C

Vapor Pressure:

4.37X10-7 mm Hg at 25 deg C (est)

Toxicity:

LD50 orl-mus: 2200 mg/kg BRXXAA #5135746

Henrys Law Constant:

Henry's Law constant = 9.41X10-12 atm-cu m/mol at 25 °C (est)

Experimental Properties:

Hydroxyl radical reaction rate constant = 1.12X10-10 cu cm/molec-sec at 25 °C (est)|Ozone radical reaction rate constant = 2.4X10-17 cu cm/molec-sec at 25 °C (est)

See More Magnolol Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Serious eye damage, Category 1

Specific target organ toxicity â single exposure, Category 3

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H315 Causes skin irritation H318 Causes serious eye damage H335 May cause respiratory irritation H411 Toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell. P391 Collect spillage.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Magnolol Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Year of Establishment:
2019

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Mexico	magnolol 98% white powder magnolol Staherb	100 KG	Nov 14, 2023

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Magnolol

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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